Haiyong Zhao
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View article: Protective Effects of Astaxanthin on Thioacetamide-Induced Hepatopancreatic Damage in Procambarus clarkii: Insights from Biochemical, Histological, and Metabolomic Analyses
Protective Effects of Astaxanthin on Thioacetamide-Induced Hepatopancreatic Damage in Procambarus clarkii: Insights from Biochemical, Histological, and Metabolomic Analyses Open
The hepatopancreas of Procambarus clarkii plays a crucial role in metabolism and immune response, encompassing vital physiological functions. In our study, we established a hepatopancreatic injury model using thioacetamide (TAA) and evalua…
View article: A Browser Fingerprint Authentication Scheme Based on the Browser Cache Side-Channel Technology
A Browser Fingerprint Authentication Scheme Based on the Browser Cache Side-Channel Technology Open
Users encounter various threats, such as cross-site scripting attacks and session hijacking, when they perform login operations in the browser. These attacks pose significant risks to the integrity and confidentiality of personal data. The…
View article: Chemically induced cell plasticity enables the generation of high-fidelity embryo model
Chemically induced cell plasticity enables the generation of high-fidelity embryo model Open
Summary Embryo models open exciting opportunities for improving our understanding of development and advancing medicine. However, current models depend on intricate procedures and the integration of separately generated cell types. Here, w…
View article: Genetic Mapping and QTL Analysis of Fruit Traits in Melon (Cucumis melo L.)
Genetic Mapping and QTL Analysis of Fruit Traits in Melon (Cucumis melo L.) Open
Melon (Cucumis melo L.) is an important horticultural cash crop and its quality traits directly affect consumer choice and market price. These traits are controlled by genetic as well as environmental factors. In this study, a quantitative…
View article: Dual-Modal Biosensor for Highly Sensitive and Selective DNA Methyltransferase Activity Detection Based on a Porous Organic Polymer-Inorganic Nanocomposite (Cu2o@Feppopbade) with High Laccase-Like Activity
Dual-Modal Biosensor for Highly Sensitive and Selective DNA Methyltransferase Activity Detection Based on a Porous Organic Polymer-Inorganic Nanocomposite (Cu2o@Feppopbade) with High Laccase-Like Activity Open
View article: svBreak: A New Approach for the Detection of Structural Variant Breakpoints Based on Convolutional Neural Network
svBreak: A New Approach for the Detection of Structural Variant Breakpoints Based on Convolutional Neural Network Open
Structural variation (SV) is an important type of genome variation and confers susceptibility to human cancer diseases. Systematic analysis of SVs has become a crucial step for the exploration of mechanisms and precision diagnosis of cance…
View article: CIRCNV: Detection of CNVs Based on a Circular Profile of Read Depth from Sequencing Data
CIRCNV: Detection of CNVs Based on a Circular Profile of Read Depth from Sequencing Data Open
Copy number variation (CNV) is a common type of structural variation in the human genome. Accurate detection of CNVs from tumor genomes can provide crucial information for the study of tumor genesis and cancer precision diagnosis. However,…
View article: Detection of Pathogenic Microbe Composition Using Next-Generation Sequencing Data
Detection of Pathogenic Microbe Composition Using Next-Generation Sequencing Data Open
Next-generation sequencing (NGS) technologies have provided great opportunities to analyze pathogenic microbes with high-resolution data. The main goal is to accurately detect microbial composition and abundances in a sample. However, high…
View article: MFCNV: A New Method to Detect Copy Number Variations From Next-Generation Sequencing Data
MFCNV: A New Method to Detect Copy Number Variations From Next-Generation Sequencing Data Open
Copy number variation (CNV) is a very important phenomenon in tumor genomes and plays a significant role in tumor genesis. Accurate detection of CNVs has become a routine and necessary procedure for a deep investigation of tumor cells and …
View article: Accurate Inference of Tumor Purity and Absolute Copy Numbers From High-Throughput Sequencing Data
Accurate Inference of Tumor Purity and Absolute Copy Numbers From High-Throughput Sequencing Data Open
Inference of absolute copy numbers in tumor genomes is one of the key points in the study of tumor genesis. However, the mixture of tumor and normal cells poses a big challenge to this task. Accurate estimation of tumor purity (i.e., the f…
View article: CRSCNV: A Cross-Model-Based Statistical Approach to Detect Copy Number Variations in Sequence Data
CRSCNV: A Cross-Model-Based Statistical Approach to Detect Copy Number Variations in Sequence Data Open
Copy number variation (CNV) is an important type of mutation in the human genome, and is significantly associated with cancer and other diseases. Accurate detection of CNVs in tumor genomes is crucial for biologists aiming to understand tu…