Hailin Xu
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View article: Gordonia bronchialis: an emerging opportunistic pathogen—a case report and comprehensive review
Gordonia bronchialis: an emerging opportunistic pathogen—a case report and comprehensive review Open
View article: Experimental study on sprayable autologous epidermal cells for promoting full-thickness skin wound healing in diabetes
Experimental study on sprayable autologous epidermal cells for promoting full-thickness skin wound healing in diabetes Open
The technology of sprayable autologous epidermal cells has been proven effective in promoting epidermal regeneration and healing chronic refractory wounds. However, its underlying impact in diabetic wound healing remains less understood. T…
View article: All-inside arthroscopic procedures for chronic lateral ankle instability: evidence-based clinical practice guidelines
All-inside arthroscopic procedures for chronic lateral ankle instability: evidence-based clinical practice guidelines Open
Background All-inside arthroscopic procedures are now frequently employed to manage chronic lateral ankle instability (CLAI) with satisfactory functional outcomes. Currently, no evidence-based guidelines exist for all-inside arthroscopic p…
View article: Trend analysis and cross-national inequity analysis of immune-mediated inflammatory diseases in children and adolescents aged 10–24 from 1990 to 2021
Trend analysis and cross-national inequity analysis of immune-mediated inflammatory diseases in children and adolescents aged 10–24 from 1990 to 2021 Open
View article: Morphological and clinical study of lateral malleolus fractures based on fracture mapping: a retrospective study
Morphological and clinical study of lateral malleolus fractures based on fracture mapping: a retrospective study Open
View article: A novel and alternative treatment method for moderate diabetic foot ulcer: tibial periosteal distraction
A novel and alternative treatment method for moderate diabetic foot ulcer: tibial periosteal distraction Open
TPD surgery technique is a simple procedure that significantly increases the efficacy and reduces the complications of moderate diabetic foot ulcer patients, which could accelerate the formation of collateral circulation.
View article: Comparison of Ultrasound-guided Transverse Carpal Ligament Release via Different Approaches in Carpal Tunnel Syndrome: A Prospective, Randomized, Controlled Trial
Comparison of Ultrasound-guided Transverse Carpal Ligament Release via Different Approaches in Carpal Tunnel Syndrome: A Prospective, Randomized, Controlled Trial Open
BACKGROUND: Ultrasound-guided transverse carpal ligament (TCL) needle release has been demonstrated to be an effective treatment for carpal tunnel syndrome (CTS). However, no existing evidence has investigated the comparative efficacy of d…
View article: The trend analysis of HIV and other sexually transmitted infections among the elderly aged 50 to 69 years from 1990 to 2030
The trend analysis of HIV and other sexually transmitted infections among the elderly aged 50 to 69 years from 1990 to 2030 Open
Overall, despite the evident decline in incidence, mortality rates, and DALYs, the prevalence of HIV and other STI among the elderly is rising, and both demonstrated significant trend variations across different ages, genders, SDI regions,…
View article: Lung Single-Cell Transcriptomics Offers Insights into the Pulmonary Interstitial Toxicity Caused by Silica Nanoparticles
Lung Single-Cell Transcriptomics Offers Insights into the Pulmonary Interstitial Toxicity Caused by Silica Nanoparticles Open
The adverse respiratory outcomes motivated by silica nanoparticles (SiNPs) exposure have received increasing attention. Herein, we aim to elucidate the interplay of diverse cell populations in the lungs and key contributors in triggering l…
View article: A multi-stage semi-supervised learning for ankle fracture classification on CT images
A multi-stage semi-supervised learning for ankle fracture classification on CT images Open
Because of the complicated mechanism of ankle injury, it is very difficult to diagnose ankle fracture in clinic. In order to simplify the process of fracture diagnosis, an automatic diagnosis model of ankle fracture was proposed. Firstly, …
View article: Clinical guideline on the third generation minimally invasive surgery for hallux valgus
Clinical guideline on the third generation minimally invasive surgery for hallux valgus Open
Minimally invasive surgery for hallux valgus correction, has been attracting great interests in the recent decades, due to the potential benefits of less pain, decreased recovery times, smaller scars with better cosmesis, and improved earl…
View article: Surgical management of chronic Achilles tendon rupture: evidence-based guidelines
Surgical management of chronic Achilles tendon rupture: evidence-based guidelines Open
View article: Neutrophil peptide 1 accelerates the clearance of degenerative axons during Wallerian degeneration by activating macrophages after peripheral nerve crush injury
Neutrophil peptide 1 accelerates the clearance of degenerative axons during Wallerian degeneration by activating macrophages after peripheral nerve crush injury Open
JOURNAL/nrgr/04.03/01300535-202408000-00036/figure1/v/2025-05-18T184447Z/r/image-tiff Macrophages play an important role in peripheral nerve regeneration, but the specific mechanism of regeneration is still unclear. Our preliminary finding…
View article: Analysis of Risk Factors for in‐hospital Death in Elderly Patients with <scp>TEXAS</scp> Stage 3 and 4 Diabetic Foot Ulcers after Tibial Transverse Translation: A Case–Control Study
Analysis of Risk Factors for in‐hospital Death in Elderly Patients with <span>TEXAS</span> Stage 3 and 4 Diabetic Foot Ulcers after Tibial Transverse Translation: A Case–Control Study Open
Objective Chinese physicians developed the Tibial Transverse Transport (TTT) technique to treat diabetic foot ulcers with more than 90% effective rate. But this method still could not avoid the in‐hospital death of patients. This study ado…
View article: The Reliability and Accuracy of the Medial Malleolar Fracture Classification Based on <scp>3D CT</scp> Reconstruction
The Reliability and Accuracy of the Medial Malleolar Fracture Classification Based on <span>3D CT</span> Reconstruction Open
Objective There is a new medial malleolar fracture classification based on 3D CT reconstruction. However, there is no study assessing the reliability and accuracy of the new classification system and comparison between the new and the clas…
View article: Mid-term follow-up evaluation of a new arthroscopic Broström procedure for chronic lateral ankle instability
Mid-term follow-up evaluation of a new arthroscopic Broström procedure for chronic lateral ankle instability Open
View article: Posterior malleolus fracture: a mid-term follow-up
Posterior malleolus fracture: a mid-term follow-up Open
Background The treatment of posterior malleolar fractures is changing rapidly, and the evidence base is still catching up. This study aimed to assess the mid-term prognosis of posterior malleolar fractures based on different morphological …
View article: Additional file 2 of The prognostic value and immune correlation of IL18 expression and promoter methylation in renal cell carcinoma
Additional file 2 of The prognostic value and immune correlation of IL18 expression and promoter methylation in renal cell carcinoma Open
Additional file 2. The supplementary tables in this study.
View article: S-Nitrosylation-mediated coupling of DJ-1 with PTEN induces PI3K/AKT/mTOR pathway-dependent keloid formation
S-Nitrosylation-mediated coupling of DJ-1 with PTEN induces PI3K/AKT/mTOR pathway-dependent keloid formation Open
Background Keloids are aberrant dermal wound healing characterized by invasive growth, extracellular matrix deposition, cytokine overexpression and easy recurrence. Many factors have been implicated as pathological causes of keloids, parti…
View article: Silica nanoparticles aggravated the metabolic associated fatty liver disease through disturbed amino acid and lipid metabolisms-mediated oxidative stress
Silica nanoparticles aggravated the metabolic associated fatty liver disease through disturbed amino acid and lipid metabolisms-mediated oxidative stress Open
View article: A Better Treatment for Moderate to Severe Hallux Valgus: Scarf + Akin Osteotomy Combined with Lateral Soft Tissue Release in a Single Medial Incision
A Better Treatment for Moderate to Severe Hallux Valgus: Scarf + Akin Osteotomy Combined with Lateral Soft Tissue Release in a Single Medial Incision Open
Objective Traditional lateral soft tissue release (LSTR) was conducted by an additional dorsal first web incision, as the malformed thick scar and neuritis were common after surgery. A new method of lateral soft tissue release in a single …
View article: Delay between admission and surgery as a potential risk factor for postoperative morbidity and mortality in elderly patients with hip fractures: A retrospective study
Delay between admission and surgery as a potential risk factor for postoperative morbidity and mortality in elderly patients with hip fractures: A retrospective study Open
The incidence of postoperative morbidity and mortality in elderly patients with hip fracture is usually the result of multiple factors, surgeons should pay attention to the patient's age, postoperative wound status and surgical delay time,…
View article: Analysis of the Effect of Antibiotic Bone Cement in the Treatment of Diabetic Foot Ulcer through Tibia Transverse Transport
Analysis of the Effect of Antibiotic Bone Cement in the Treatment of Diabetic Foot Ulcer through Tibia Transverse Transport Open
Objective To explore the efficacy of antibiotic bone cement (ABC) combined with the modified tibial transverse transport (mTTT) on the treatment of severe diabetic foot with infection. Methods A retrospective cohort study was conducted of …
View article: Rotation scarf + Akin osteotomy for severe hallux valgus with a new evaluation index: distance between the first and second metatarsals
Rotation scarf + Akin osteotomy for severe hallux valgus with a new evaluation index: distance between the first and second metatarsals Open
Background Although rotation scarf + Akin osteotomy has been described for correcting hallux valgus deformity, the treatment efficacy of rotation scarf + Akin osteotomy for severe hallux valgus should be further studied. The purpose of our…
View article: Bioinformatic Analysis Reveals Hub Immune-Related Genes of Diabetic Foot Ulcers
Bioinformatic Analysis Reveals Hub Immune-Related Genes of Diabetic Foot Ulcers Open
Diabetic foot ulcer (DFU) is a complex and devastating complication of diabetes mellitus that are usually stagnant in the inflammatory phase. However, oral wound healing, which is characterized by a rapid and scarless healing process, is r…
View article: Establishment of a finite element model and stress analysis of intra-articular impacted fragments in posterior malleolar fractures
Establishment of a finite element model and stress analysis of intra-articular impacted fragments in posterior malleolar fractures Open
Background Intra-articular impacted fragments (IAIFs) are considered articular surface fragments resulting from impact and compressive forces. The malreduction of IAIFs in posterior malleolar fractures has been associated with talar sublux…
View article: CID16020046, a GPR55 antagonist, attenuates sepsis‑induced acute kidney injury
CID16020046, a GPR55 antagonist, attenuates sepsis‑induced acute kidney injury Open
Acute kidney injury (AKI) is the most common and serious complication of sepsis, and it is also the main cause of mortality in patients with sepsis. The G protein‑coupled receptor 55 (GPR55) inhibitor CID16020046 was found to suppress the …
View article: Silica Nanoparticles Induce Cardiac Injury and Dysfunction Via ROS/Ca <sup>2+</sup>/CaMKII Signaling
Silica Nanoparticles Induce Cardiac Injury and Dysfunction Via ROS/Ca <sup>2+</sup>/CaMKII Signaling Open
View article: Long-Term Respiratory Exposure to Silica Nanoparticles Promoted Systemic Inflammation and Progression of Fibrosis in a Susceptible Mouse Model
Long-Term Respiratory Exposure to Silica Nanoparticles Promoted Systemic Inflammation and Progression of Fibrosis in a Susceptible Mouse Model Open
View article: Morphological analysis of posterior malleolar fractures with intra-articular impacted fragment in computed tomography scans
Morphological analysis of posterior malleolar fractures with intra-articular impacted fragment in computed tomography scans Open