Haim H. Bau
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View article: Smartphone-Linked and Electricity-Free Platforms for Rapid Colorimetric Molecular Detection of Poultry Respiratory Viruses at the Point of Need
Smartphone-Linked and Electricity-Free Platforms for Rapid Colorimetric Molecular Detection of Poultry Respiratory Viruses at the Point of Need Open
Efficient control measures for respiratory diseases in humans and farm animals require accurate, specific, and rapid diagnostics. Traditional PCR-based molecular diagnostics are restricted to centralized laboratories, which results in sign…
View article: Onsager coefficients for liquid metal flow in a conduit under a magnetic field
Onsager coefficients for liquid metal flow in a conduit under a magnetic field Open
We analyze the flow of room and near room-temperature liquid metals in shallow, long rectangular conduits with two insulating and two perfectly conducting walls under a uniform magnetic field perpendicular to the flow direction and the ins…
View article: Molecular Detection of Respiratory Tract Viruses in Chickens at the Point of Need by Loop-Mediated Isothermal Amplification (LAMP)
Molecular Detection of Respiratory Tract Viruses in Chickens at the Point of Need by Loop-Mediated Isothermal Amplification (LAMP) Open
Accurate and timely molecular diagnosis of respiratory diseases in chickens is essential for implementing effective control measures, preventing the spread of diseases within poultry flocks, minimizing economic loss, and guarding food secu…
View article: Self-actuated microfluidic chiplet for two-stage multiplex nucleic acid amplification assay
Self-actuated microfluidic chiplet for two-stage multiplex nucleic acid amplification assay Open
Self-actuated chiplet for Penn-RAMP assay.
View article: Editorial: Rapid detection of fungi, microbial, and viral pathogens based on emerging biosensing technology
Editorial: Rapid detection of fungi, microbial, and viral pathogens based on emerging biosensing technology Open
EDITORIAL article Front. Bioeng. Biotechnol., 17 November 2022Sec. Biosensors and Biomolecular Electronics https://doi.org/10.3389/fbioe.2022.1067322
View article: Applications of Magneto Electrochemistry and Magnetohydrodynamics in Microfluidics
Applications of Magneto Electrochemistry and Magnetohydrodynamics in Microfluidics Open
Magnetic fields affect electrolytes in diverse ways. This paper focuses on the interactions among electric, magnetic, and flow fields and the applications of the resulting phenomena in microfluidics. When an electrical current is transmitt…
View article: Sensitive, Single-Pot, Two-Stage Assay for Hepatitis Viruses
Sensitive, Single-Pot, Two-Stage Assay for Hepatitis Viruses Open
When left untreated, hepatitis B virus (HBV) and hepatitis C virus (HCV) infections may cause severe illnesses. Since these infections remain asymptomatic for many years, routine screening of populations at risk is critical for therapy ini…
View article: Molecular Detection of Infectious Laryngotracheitis Virus in Chickens with a Microfluidic Chip
Molecular Detection of Infectious Laryngotracheitis Virus in Chickens with a Microfluidic Chip Open
Infectious laryngotracheitis (ILT) is a viral disease of chickens’ respiratory system that imposes considerable financial burdens on the chicken industry. Rapid, simple, and specific detection of this virus is crucial to enable proper cont…
View article: Single- and Two-Stage, Closed-Tube, Point-of-Care, Molecular Detection of SARS-CoV-2
Single- and Two-Stage, Closed-Tube, Point-of-Care, Molecular Detection of SARS-CoV-2 Open
Short of a vaccine, frequent and rapid testing, preferably at home, is the most effective strategy to contain the COVID-19 pandemic. Herein, we report on single-stage and two-stage molecular diagnostic tests that can be carried out with si…
View article: Detection of <i>Streptococcus equi</i> subsp. <i>equi</i> in guttural pouch lavage samples using a loop‐mediated isothermal nucleic acid amplification microfluidic device
Detection of <i>Streptococcus equi</i> subsp. <i>equi</i> in guttural pouch lavage samples using a loop‐mediated isothermal nucleic acid amplification microfluidic device Open
Background Rapid point‐of‐care (POC) detection of Streptococcus equi subsp. equi ( S. equi ) would theoretically reduce the spread of strangles by identifying index and carrier horses. Hypothesis That the eqbE isothermal amplification (LAM…
View article: Additional file 2 of Caenorhabditis elegans exhibits positive gravitaxis
Additional file 2 of Caenorhabditis elegans exhibits positive gravitaxis Open
Additional file 2: Raw Data.
View article: A portable, 3D printed, microfluidic device for multiplexed, real time, molecular detection of the porcine epidemic diarrhea virus, transmissible gastroenteritis virus, and porcine deltacoronavirus at the point of need
A portable, 3D printed, microfluidic device for multiplexed, real time, molecular detection of the porcine epidemic diarrhea virus, transmissible gastroenteritis virus, and porcine deltacoronavirus at the point of need Open
The porcine epidemic diarrhea virus (PEDV), transmissible gastroenteritis virus (TGEV), and porcine deltacoronavirus (PDCoV) are coronaviruses (CoVs) of neonatal pigs that cause great economic losses to pig farms and pork processors.
View article: Electricity-free chemical heater for isothermal nucleic acid amplification with applications in COVID-19 home testing
Electricity-free chemical heater for isothermal nucleic acid amplification with applications in COVID-19 home testing Open
Electricty-free incubation of isothermal enzymatic amplification with a composite comprised of exothermic reactants for heat generation and phase change material for temperature regulation.
View article: Two stage, nested isothermal amplification in a single tube
Two stage, nested isothermal amplification in a single tube Open
Sensitive, specific and rapid molecular diagnosis of respiratory diseases in animals and humans is critical to facilitate appropriate control measures and treatment.
View article: A Single and Two-Stage, Closed-Tube, Molecular Test for the 2019 Novel Coronavirus (COVID-19) at Home, Clinic, and Points of Entry
A Single and Two-Stage, Closed-Tube, Molecular Test for the 2019 Novel Coronavirus (COVID-19) at Home, Clinic, and Points of Entry Open
The 2019 novel coronavirus (COVID-19) is a newly emerged strain that has never been found in humans before. At present, the laboratory-based reverse transcription-polymerase chain reaction (RT-PCR) is the main method to confirm COVID-19 in…
View article: A Single and Two-Stage, Closed-Tube, Molecular Test for the 2019 Novel Coronavirus (COVID-19) at Home, Clinic, and Points of Entry
A Single and Two-Stage, Closed-Tube, Molecular Test for the 2019 Novel Coronavirus (COVID-19) at Home, Clinic, and Points of Entry Open
The 2019 novel coronavirus (COVID-19) is a newly emerged strain that has never been found in humans before. At present, the laboratory-based reverse transcription-polymerase chain reaction (RT-PCR) is the main method to confirm COVID-19 in…
View article: Highly specific enrichment of rare nucleic acid fractions using Thermus thermophilus argonaute with applications in cancer diagnostics
Highly specific enrichment of rare nucleic acid fractions using Thermus thermophilus argonaute with applications in cancer diagnostics Open
Detection of disease-associated, cell-free nucleic acids in body fluids enables early diagnostics, genotyping and personalized therapy, but is challenged by the low concentrations of clinically significant nucleic acids and their sequence …
View article: <i>Caenorhabditis elegans</i>Exhibits Positive Gravitaxis
<i>Caenorhabditis elegans</i>Exhibits Positive Gravitaxis Open
Whether or not the micro swimmer Caenorhabditis elegans senses and respond to gravity is unknown. We find that C. elegans aligns its swimming direction with that of the gravity vector (positive gravitaxis). When placed in an aqueous soluti…
View article: MOESM6 of Automated analysis of evolving interfaces during in situ electron microscopy
MOESM6 of Automated analysis of evolving interfaces during in situ electron microscopy Open
Additional file 6: Code S1. Code S1 is a Mathematica notebook file that gives an overview of the image processing work flow described in the text. It can be used with Video S2 to generate the raw image assets need to construct Figs. 1, 2 i…
View article: MOESM8 of Automated analysis of evolving interfaces during in situ electron microscopy
MOESM8 of Automated analysis of evolving interfaces during in situ electron microscopy Open
Additional file 8: Code S3. Code S3 is a Mathematica notebook file that gives an overview of the image processing work flow described in the text. It can be used with Video S4 to generate the raw image assets need to construct Fig. 5 in th…
View article: MOESM7 of Automated analysis of evolving interfaces during in situ electron microscopy
MOESM7 of Automated analysis of evolving interfaces during in situ electron microscopy Open
Additional file 7: Code S2. Code S2 is a Mathematica notebook file that gives an overview of the image processing work flow described in the text. It can be used with Video S3 to generate the raw image assets need to construct Fig. 3 in th…
View article: MOESM9 of Automated analysis of evolving interfaces during in situ electron microscopy
MOESM9 of Automated analysis of evolving interfaces during in situ electron microscopy Open
Additional file 9: Code S4. Code S4 is a Mathematica notebook file that gives an overview of the image processing work flow described in the text. It can be used with Video S5 to generate the raw image assets need to construct Fig. 6 in th…
View article: Highly specific enrichment of rare nucleic acids using<i>Thermus thermophilus</i>Argonaute
Highly specific enrichment of rare nucleic acids using<i>Thermus thermophilus</i>Argonaute Open
Characterization of disease-associated, cell-free nucleic acids (liquid biopsy) provides a powerful, minimally-invasive means for early detection, genotyping, and personalized therapy; but is challenged by alleles of interest differing by …
View article: Dynamics of intracellular stress-induced tRNA trafficking
Dynamics of intracellular stress-induced tRNA trafficking Open
Stress is known to induce retrograde tRNA translocation from the cytoplasm to the nucleus but translocation kinetics and tRNA-spatial distribution have not been characterized previously. We microinject fluorescently-labeled tRNA into livin…