Explanipedia

High-power organic light-emitting diodes for photodynamic therapy in a mouse model of oral squamous cell carcinoma Open

Jiechen Zhang, 順子三枝, Yibin Xu, Yingguang Zhu, Yonglan Hu , et al. · 2025

Effective light delivery with precise control is critical for achieving safe and efficient photodynamic therapy (PDT). Organic light-emitting diodes (OLEDs) represent an attractive novel light source for PDT due to their large-area, unifor…

Optogenetic technology: breakthroughs and challenges from basic research to clinical translation Open

Hongyou Zhao, Yue Hui, Wenxin Chou, Sen Yang, Yidi Liu , et al. · 2025

Three-dimensional C-scan-based generation adversarial network with synthetic input to improve optical coherence tomography angiography Open

Jingjiang Xu, Zhongwu Feng, Haixia Qiu, Peijun Tang, Kai Gao , et al. · 2025

It demonstrates that the proposed 3DCS-GAN can greatly improve vascular visualization in the deep layer, provide better image quality than the multiple averaged OCTA images, and achieve superior image enhancement for volumetric OCTA data.

Low-power versus high-power laser for holmium laser enucleation of prostate: systematic review and meta-analysis Open

Liping Chen, Changqing Chen, Congran Li, Zhijia Liu, Haixia Qiu , et al. · 2025

The effect of 807‐nm light‐emitting diode photobiomodulation on peripheral nerve injury Open

Biao Chang, Qi Quan, Xinyue Liang, Yanjun Guan, Xing Xiong , et al. · 2025

Photobiomodulation (PBM) has demonstrated potential in promoting peripheral nerve regeneration. However, there is a limited and inconclusive study on the application of light‐emitting diode (LED) for nerve injury repair. In this study, we …

Investigating the impact of different time delays between OCT signal and k-clock signal on the structural and vascular imaging in SS-OCT Open

Miaohua Chen, Z. H. Lu, Peijun Tang, Gongpu Lan, Yanping Huang , et al. · 2025

High-quality swept-source optical coherence tomography (SS-OCT) imaging systems require precise synchronization between the OCT signal and the k-clock signal. However, in practical applications, an uncertain time delay between these signal…

Topical 5-aminolevulinic acid-mediated photodynamic therapy versus loop electrosurgical excision procedure in the treatment of cervical intraepithelial neoplasia Open

Yidi Liu, Yi Li, Huan Wu, Ying Wang, Jing Zeng , et al. · 2024

Monitoring of microvascular calcification by time-resolved photoacoustic microscopy Open

Haigang Ma, Yinshi Yu, Yahui Zhu, Hongjun Wu, Haixia Qiu , et al. · 2024

Visualization enhancement by PCA-based image fusion for skin burns assessment in polarization-sensitive OCT Open

Jingjiang Xu, Mingtao Zhu, Peijun Tang, Junyun Li, Kai Gao , et al. · 2024

Polarization-sensitive optical coherence tomography (PS-OCT) is a functional imaging tool for measuring tissue birefringence characteristics. It has been proposed as a potentially non-invasive technique for evaluating skin burns. However, …

Long-term ultraviolet B irradiation at 297 nm with light-emitting diode improves bone health via vitamin D regulation Open

Wenwen Liu, Ying Wang, Haixia Qiu, Defu Chen, Shengnan Wu , et al. · 2024

Ultraviolet radiation is the primary determinant for vitamin D synthesis. Sunlight is inefficient and poses a risk, particularly for long-term exposure. In this study, we screened the most favorable wavelength for vitamin D synthesis among…

Quantitative characterization of vascular targeted photodynamic therapy efficiency for port-wine stains using image processing techniques Open

Lin Li, Junbo Xi, Haixia Qiu, Buhong Li · 2024

Vascular targeted photodynamic therapy (V-PDT) is a clinically approved therapeutic approach for treating vascular-related diseases, such as port-wine stains (PWS). For accurate treatment, various light doses are required for different les…

Quantitative analysis of lesion images to evaluate the efficiency of vascular-targeted photodynamic therapy for port-wine stains: Four case reports Open

Lin Li, Junbo Xi, Haixia Qiu, Buhong Li · 2024

A new method to quantify the Euclidean distances and correlation coefficients has been proposed, which is promising for the quantitative analysis of V-PDT efficiency for PWS.

Photodynamic therapy of vaginal intraepithelial neoplasia—How to do it? Open

Xiaoyun Wang, Haixia Qiu, Huiqi Zhan, Zheng Huang · 2024

Vaginal intraepithelial neoplasia (VaIN or VAIN), a rare precancerous disease, is difficult to treat. Photodynamic therapy (PDT) is a relatively new modality for the treatment of various precancerous mucosal lesions of the lower genital or…

Monitoring of Microvascular Calcification by Time-Resolved Photoacoustic Microscopy Open

Haigang Ma, Yinshi Yu, Yahui Zhu, Haixia Qiu, Ying Gu , et al. · 2024

Photodynamic Therapy-Induced Anti-Tumor Immunity: Influence Factors and Synergistic Enhancement Strategies Open

Wenxin Chou, Tianzhen Sun, Nian Peng, Zixuan Wang, Defu Chen , et al. · 2023

Photodynamic therapy (PDT) is an approved therapeutic procedure that exerts cytotoxic activity towards tumor cells by activating photosensitizers (PSs) with light exposure to produce reactive oxygen species (ROS). Compared to traditional t…

4D spectral-spatial computational photoacoustic dermoscopy Open

Yang Gao, Ting Feng, Haixia Qiu, Ying Gu, Qian Chen , et al. · 2023

Inside Cover Open

Kerui Li, Qijia Wu, Shiyu Feng, Hongyou Zhao, Wei Jin , et al. · 2023

This study explored the feasibility of diffuse reflectance spectroscopy (DRS) for discrimination between brain cancer and noncancer tissues. Our method could achieve a sensitivity of 93% and specificity of 95% for discriminating high‐grade…

Pulsed dye laser (PDL) versus photodynamic therapy (PDT) for the treatment of port wine stain (PWS): a systematic review and meta-analysis Open

Yidi Liu, Ying Wang, Jing Zeng, Hui Li, Haixia Qiu , et al. · 2023

Objective: Vascular lesions, such as port wine stain (PWS), lead to facial and psychological problems that require careful and timely treatments. This review aims to compare two mainstream methods pulsed dye laser (PDL) therapy and photody…

Preventing Post-Traumatic Stress Disorder (PTSD) in rats with pulsed 810 nm laser transcranial phototherapy Open

Hongyou Zhao, Yi Li, Ting Luo, Wenxin Chou, Tianzhen Sun , et al. · 2023

Post-traumatic stress disorder (PTSD) is a debilitating condition that occurs following exposure to traumatic events. Current treatments, such as psychological debriefing and pharmacotherapy, often have limited efficacy and may result in u…

Tissue optical clearing enhances efficacy of vascular targeted photodynamic therapy of mouse dorsal skin Open

Ying Liu, Qiushi Wang, Yidi Liu, Ying Wang, Haixia Qiu , et al. · 2023

Vascular-targeted photodynamic therapy (V-PDT) is an effective treatment for port wine stains (PWS). However, repeated treatment is usually needed to achieve optimal treatment outcomes, possibly due to the limited treatment light penetrati…

A Generic and Effective System Dispersion Compensation Method: Development and Validation in Visible-Light OCT Open

Jiarui Wang, Chao Xu, Shaodi Zhu, Defu Chen, Haixia Qiu , et al. · 2023

Compared with optical coherence tomography (OCT) in the near-infrared domain, the visible-light OCT (vis-OCT) system affords a higher axial resolution for discerning subtle pathological changes associated with early diseases. However, the …

Anti-PD1 antibody and not anti-LAG-3 antibody improves the antitumor effect of photodynamic therapy for treating metastatic breast cancer Open

Shan Long, Yibing Zhao, Yuanyuan Xu, Bo Wang, Haixia Qiu , et al. · 2023

Photodynamic therapy (PDT) has limited effects in treating metastatic breast cancer. Immune checkpoints can deplete the function of immune cells; however, the expression of immune checkpoints after PDT is unclear. This study investigates w…

Topical 5-Aminolevulinic Acid-Mediated Photodynamic Therapy versus Loop Electrosurgical Excision Procedure in the Treatment of Cervical Intraepithelial Neoplasia Open

Yidi Liu, Yi Li, Jieyang Xu, Huan Wu, Ying Wang , et al. · 2023

Objective. To compare effectiveness of topical 5-aminolevulinic acid-mediated photodynamic therapy (5-ALA PDT) and loop electrosurgical excision procedure (LEEP) among patients with cervical intraepithelial neoplasia (CIN). Methods. We ret…

Deep‐learning visualization enhancement method for optical coherence tomography angiography in dermatology Open

Jingjiang Xu, Xing Yuan, Yanping Huang, Jia Qin, Gongpu Lan , et al. · 2023

Optical coherence tomography angiography (OCTA) in dermatology usually suffers from low image quality due to the highly scattering property of the skin, the complexity of cutaneous vasculature, and limited acquisition time. Deep‐learning m…

Ultrasonic irradiation enhanced the efficacy of antimicrobial photodynamic therapy against methicillin-resistant Staphylococcus aureus biofilm Open

Yixuan Xu, Shiyang Liu, Hongyou Zhao, Yi Li, Cui Chao , et al. · 2023

Topical 5-Aminolevulinic Acid-Mediated Photodynamic Therapy versus Loop Electrosurgical Excision Procedure in the Treatment of Cervical Intraepithelial Neoplasia: A retrospective study, 2012–2019 Open

Yidi Liu, Yi Li, Jieyang Xu, Huan Wu, Ying Wang , et al. · 2022

Objective: To compare effectiveness of topical 5-aminolevulinic acid-mediated photodynamic therapy (5-ALA PDT) and loop electrosurgical excision procedure (LEEP) among patients with cervical intraepithelial neoplasia (CIN). Design：Retrospe…

Image enhancement of wide-field retinal optical coherence tomography angiography by super-resolution angiogram reconstruction generative adversarial network Open

Xing Yuan, Yanping Huang, Lin An, Jia Qin, Gongpu Lan , et al. · 2022

Wide-field retinal optical coherence tomography angiography (OCTA) usually suffers from low image resolution in clinical practice because of insufficient lateral sampling. In this study, we develop a deep-learning-based method named super-…

Immune response induced by hematoporphyrin derivatives mediated photodynamic therapy: Immunogenic cell death and elevated costimulatory molecules Open

Shan Long, Yibing Zhao, Yuanyuan Xu, Hui Li, Hongyou Zhao , et al. · 2022

Photodynamic therapy (PDT) not only destroys tumor cells directly but also induced anti-tumor immune response through damage-associated molecular patterns (DAMPs). It is reported that anti-tumor response was associated with light dose and …

A Novel Pyroptotic and Inflammatory Gene Signature Predicts the Prognosis of Cutaneous Melanoma and the Effect of Anticancer Therapies Open

Yujian Xu, Youbai Chen, Zehao Niu, Jiahua Xing, Yang Zheng , et al. · 2022

Purpose The purpose of this study was to construct a gene signature comprising genes related to both inflammation and pyroptosis (GRIPs) to predict the prognosis of patients with cutaneous melanoma patients and the efficacy of immunotherap…

Optimization of photo-biomodulation therapy for wound healing of diabetic foot ulcers in vitro and in vivo Open

Qianqian Chen, Jichun Yang, Huijuan Yin, Yingxin Li, Haixia Qiu , et al. · 2022

Unclear optical parameters make photo-biomodulation (PBM) difficult to implement in diabetic foot ulcer (DFU) clinically. Here, 12 wavelengths (400–900 nm) were used to conduct PBM to heal DFU wounds in vitro and in vivo. PBM at 10 mW/cm 2…

Haixia Qiu YOU? Author Swipe