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View article: Standalone short-coil embolization of the middle meningeal artery for subdural hematomas: Efficient, safe, and radiation-sparing
Standalone short-coil embolization of the middle meningeal artery for subdural hematomas: Efficient, safe, and radiation-sparing Open
This study represents the largest single-center series of standalone coil embolization for NASDH. The technique demonstrated excellent safety, hematoma resolution, and procedural efficiency.
View article: ADG-SleepNet: A Symmetry-Aware Multi-Scale Dilation-Gated Temporal Convolutional Network with Adaptive Attention for EEG-Based Sleep Staging
ADG-SleepNet: A Symmetry-Aware Multi-Scale Dilation-Gated Temporal Convolutional Network with Adaptive Attention for EEG-Based Sleep Staging Open
The increasing demand for portable health monitoring has highlighted the need for automated sleep staging systems that are both accurate and computationally efficient. However, most existing deep learning models for electroencephalogram (E…
View article: Aberrant white matter and subcortical gray matter functional network connectivity associated with static and dynamic characteristics in subjects with temporal lobe epilepsy
Aberrant white matter and subcortical gray matter functional network connectivity associated with static and dynamic characteristics in subjects with temporal lobe epilepsy Open
Temporal lobe epilepsy (TLE) is a common type of epilepsy, with seizures primarily originating in the deep temporal lobe. This condition results in changes in connectivity across gray matter (GM), and white matter (WM) regions. This altere…
View article: Clinical Value of ChatGPT for Epilepsy Presurgical Decision-Making: Systematic Evaluation of Seizure Semiology Interpretation
Clinical Value of ChatGPT for Epilepsy Presurgical Decision-Making: Systematic Evaluation of Seizure Semiology Interpretation Open
Background For patients with drug-resistant focal epilepsy, surgical resection of the epileptogenic zone (EZ) is an effective treatment to control seizures. Accurate localization of the EZ is crucial and is typically achieved through compr…
View article: Use of flow-diverting stents in the treatment of ruptured intracranial artery dissections
Use of flow-diverting stents in the treatment of ruptured intracranial artery dissections Open
Background: Flow-diverting stents have rapidly become widespread as the preferred treatment for intracranial aneurysms. They function by optimizing blood flow within the parent vessel to reduce shear stress in the aneurysm, facilitating th…
View article: Flow Diverter Assisted Embolization of Ruptured Aneurysms is Associated with Increased Hemorrhagic Complications: Prognostic Factors and Outcomes in Neuroendovascular Treatment of Subarachnoid Hemorrhages
Flow Diverter Assisted Embolization of Ruptured Aneurysms is Associated with Increased Hemorrhagic Complications: Prognostic Factors and Outcomes in Neuroendovascular Treatment of Subarachnoid Hemorrhages Open
PED is associated with a higher incidence of systemic hemorrhagic complications, particularly gastrointestinal and respiratory tract bleeding, compared to coil embolization. Patients undergoing PED require careful patient selection and pos…
View article: Flow diversion for acutely ruptured intracranial aneurysms: A single-center retrospective analysis of 30 consecutive cases
Flow diversion for acutely ruptured intracranial aneurysms: A single-center retrospective analysis of 30 consecutive cases Open
OBJECTIVES: When presented with acutely ruptured aneurysms, neurosurgeons may elect to use flow diverters (FDs). However, with the limited evidence concerning their safety and the potential thromboembolic and hemorrhagic complications, the…
View article: µFIX – Enabling Combinations of Concurrent Optogenetics and Lock-in Amplification Fiber Photometry via Removal of Optogenetic Stimulation Crosstalk
µFIX – Enabling Combinations of Concurrent Optogenetics and Lock-in Amplification Fiber Photometry via Removal of Optogenetic Stimulation Crosstalk Open
Simultaneous fiber photometry and optogenetics is a powerful emerging technique for precisely studying the interactions of neuronal brain networks. However, spectral overlap between photometry and optogenetic components has severely limite…
View article: Chiari malformation with concurrent papilledema: a patient-level meta-analysis of case reports and case series
Chiari malformation with concurrent papilledema: a patient-level meta-analysis of case reports and case series Open
Background Chiari I malformation, characterized by the displacement of cerebellar tonsils, and Chiari 1.5, involving cerebellar tonsils and brainstem displacement, share symptoms with Idiopathic Intracranial Hypertension, including headach…
View article: Dynamic Nomogram for Predicting the Fall Risk of Stroke Patients: An Observational Study
Dynamic Nomogram for Predicting the Fall Risk of Stroke Patients: An Observational Study Open
Independent fall risk factors in stroke patients are age, had a fall history within the last 3 months, anxiety, and with the BBS score below 40 during rehabilitation. The dynamic nomogram prediction model for stroke patients during rehabil…
View article: The immunomodulatory role of the MAFB gene in hepatocellular carcinoma and its impact on biological activities
The immunomodulatory role of the MAFB gene in hepatocellular carcinoma and its impact on biological activities Open
MAFB plays a significant role in HCC development and immune regulation. The prognostic model combining MAFB-related immune genes provides valuable insights for predicting patient outcomes and identifying potential therapeutic targets.
View article: Stand-alone transarterial flow diversion for treatment of carotid cavernous fistulas
Stand-alone transarterial flow diversion for treatment of carotid cavernous fistulas Open
The authors' experiences suggest the efficacy and safety of FD stenting as a stand-alone treatment option for CCFs. Compared to embolization, FD stents can better preserve the parent vessel and promote healing with less associated mass eff…
View article: WITHDRAWN: EpiSemoLLM: A Fine-tuned Large Language Model for Epileptogenic Zone
WITHDRAWN: EpiSemoLLM: A Fine-tuned Large Language Model for Epileptogenic Zone Open
Withdrawal statement medRxiv has withdrawn this manuscript due to a duplicate posting of manuscript number MEDRXIV/2024/307955. Therefore, this work should not be cited as reference for the project. If you have any questions, please contac…
View article: Delayed cerebrovascular reactivity in individuals with spinal cord injury in the right inferior parietal lobe: a breath-hold functional near-infrared spectroscopy study
Delayed cerebrovascular reactivity in individuals with spinal cord injury in the right inferior parietal lobe: a breath-hold functional near-infrared spectroscopy study Open
Cerebrovascular reactivity (CVR) reflects the ability of blood vessels to dilate or constrict in response to a vasoactive stimulus, and allows researchers to assess the brain’s vascular health. Individuals with spinal cord injury (SCI) are…
View article: EpiSemoLLM: A Fine-tuned Large Language Model for Epileptogenic Zone Localization Based on Seizure Semiology with a Performance Comparable to Epileptologists
EpiSemoLLM: A Fine-tuned Large Language Model for Epileptogenic Zone Localization Based on Seizure Semiology with a Performance Comparable to Epileptologists Open
Significance Seizure semiology, the study of signs and clinical manifestations during seizure episodes, provides crucial information for inferring the location of epileptogenic zone (EZ). Given the descriptive nature of seizure semiology a…
View article: The Clinical Value of ChatGPT for Epilepsy Presurgical Decision Making: Systematic Evaluation on Seizure Semiology Interpretation
The Clinical Value of ChatGPT for Epilepsy Presurgical Decision Making: Systematic Evaluation on Seizure Semiology Interpretation Open
Background For patients with drug-resistant focal epilepsy (DRE), surgical resection of the epileptogenic zone (EZ) is an effective treatment to control seizures. Accurate localization of the EZ is crucial and is typically achieved through…
View article: Brain activation during the N-back working memory task in individuals with spinal cord injury: a functional near-infrared spectroscopy study
Brain activation during the N-back working memory task in individuals with spinal cord injury: a functional near-infrared spectroscopy study Open
Cognitive impairments have frequently been reported in individuals with spinal cord injury (SCI) across different domains such as working memory, attention, and executive function. The mechanism of cognitive impairment after SCI is not wel…
View article: Brain abscesses following carotid blowout syndrome: a case report
Brain abscesses following carotid blowout syndrome: a case report Open
We report a case of intracranial abscesses development in a patient with head and neck cancer after emergent treatment of carotid blowout syndrome with coil embolization. Our patient is a 60-year-old male who presented with hemoptysis and …
View article: Radially adjustable stent retriever for mechanical thrombectomy in acute ischemic stroke: Improved first-pass effect with rapid-inflation deflation technique
Radially adjustable stent retriever for mechanical thrombectomy in acute ischemic stroke: Improved first-pass effect with rapid-inflation deflation technique Open
Introduction Evidence for improved first-pass effect with the novel radially adjustable radio-opaque stent retriever Tigertriever is lacking. Objective To compare improvement in first pass success with Tigertriever using two different tech…
View article: Unilateral optogenetic kindling of hippocampus leads to more severe impairments of the inhibitory signaling in the contralateral hippocampus
Unilateral optogenetic kindling of hippocampus leads to more severe impairments of the inhibitory signaling in the contralateral hippocampus Open
The kindling model has been used extensively by researchers to study the neurobiology of temporal lobe epilepsy (TLE) due to its capacity to induce intensification of seizures by the progressive recruitment of additional neuronal clusters …
View article: Ictogenesis Proceeds Through Discrete Phases in Hippocampal CA1 Seizures in Mice
Ictogenesis Proceeds Through Discrete Phases in Hippocampal CA1 Seizures in Mice Open
Epilepsy is characterized by spontaneous non-provoked seizures, yet the mechanisms that trigger a seizure and allow its evolution remain underexplored. To dissect out phases of ictogenesis, we evoked hypersynchronous activity with optogene…
View article: Ictogenesis Proceeds Through Discrete Phases in Hippocampal CA1 Seizures
Ictogenesis Proceeds Through Discrete Phases in Hippocampal CA1 Seizures Open
Epilepsy is characterized by spontaneous non-provoked seizures, yet the mechanisms that trigger a seizure and allow its evolution remain underexplored. To dissect out phases implicated in the development of a seizure, we evoked hypersynchr…
View article: Comprehensive microsurgical anatomy of the middle cranial fossa: Part II—neurovascular anatomy
Comprehensive microsurgical anatomy of the middle cranial fossa: Part II—neurovascular anatomy Open
In order to master the surgical approaches to the middle cranial fossa, the surgeon needs to understand the relevant bony anatomy. However, she/he also needs to have a clear and sound understanding of the neural and vascular anatomy becaus…
View article: Comprehensive microsurgical anatomy of the middle cranial fossa: Part I—Osseous and meningeal anatomy
Comprehensive microsurgical anatomy of the middle cranial fossa: Part I—Osseous and meningeal anatomy Open
The middle cranial fossa is one of the most complex regions in neurosurgery and otolaryngology—in fact, the practice of skull base surgery originated from the need to treat pathologies in this region. Additionally, great neurosurgeons of o…