Explanipedia

Translating Milli/Microrobots with A Value-Centered Readiness Framework Open

Hakan Ceylan, Edoardo Sinibaldi, Sanjay Misra, Pankaj J. Pasricha, Dietmar W. Hutmacher · 2025

Untethered mobile milli/microrobots hold transformative potential for interventional medicine by enabling more precise and entirely non-invasive diagnosis and therapy. Realizing this promise requires bridging the gap between groundbreaking…

Multifunctional peptide nanofiber coatings enhance bone regeneration on xenograft materials Open

Hacer Eberliköse, Seher Yaylacı, Demet Kaçaroğlu, Hakan Ceylan · 2025

Conventional bone grafts such as xenografts, allografts, and synthetic substitutes are widely used in regenerative dentistry, but their biological performance remains suboptimal. To address this limitation, this study investigates the effe…

The modified asymmetric chondro-perichondrial island graft in type I tympanoplasty: A retrospective analysis of 784 patients Open

Fetih Furkan Şahin, İsa Kaya, Hakan Ceylan, Tayfun Kirazlı · 2024

X-ray fluoroscopy guided localization and steering of miniature robots using virtual reality enhancement Open

Husnu Halid Alabay, Tuan‐Anh Le, Hakan Ceylan · 2024

In developing medical interventions using untethered milli- and microrobots, ensuring safety and effectiveness relies on robust methods for real-time robot detection, tracking, and precise localization within the body. The inherent non-tra…

Designing magnetic microcapsules for cultivation and differentiation of stem cell spheroids Open

Kihak Gwon, Ether Dharmesh, Kianna M. Nguyen, Anna Marie R Schornack, José M. de Hoyos‐Vega , et al. · 2024

Human pluripotent stem cells (hPSCs) represent an excellent cell source for regenerative medicine and tissue engineering applications. However, there remains a need for robust and scalable differentiation of stem cells into functional adul…

X-ray Fluoroscopy Guided Localization and Steering of Medical Microrobots through Virtual Enhancement Open

Husnu Halid Alabay, Tuan‐Anh Le, Hakan Ceylan · 2024

In developing medical interventions using untethered milli- and microrobots, ensuring safety and effectiveness relies on robust methods for detection, real-time tracking, and precise localization within the body. However, the inherent non-…

Remotely Guided Immunobots Engaged in Anti‐Tumorigenic Phenotypes for Targeted Cancer Immunotherapy Open

Nihal Olcay Dogan, Hakan Ceylan, Eylül Suadiye, Devin Sheehan, Aslı Aydın , et al. · 2022

Building medical microrobots from the body's own cells may circumvent the biocompatibility concern and hence presents more potential in clinical applications to improve the possibility of escaping from the host defense mechanism. More impo…

3D printed personalized magnetic micromachines from patient blood–derived biomaterials Open

Hakan Ceylan, Nihal Olcay Dogan, Immihan Ceren Yasa, Mirac Nur Musaoğlu, Zeynep Kulali , et al. · 2021

Medical microrobots can be made personal by 3D printing them from patient blood–derived biomaterials.

Perlit Agregalarının Farklı Sıcaklıklarda Genleştirilmesi Üzerine Teknik Bir Analiz Open

Nükhet ŞAPCI, Hakan Ceylan · 2021

Perlit doğal olarak oluşan silis kökenli asidik özellikte volkanik bir kayaç türüdür. Perlitin en önemli özelliği belirli sıcaklıklarda ısıtıldığında genleşerek gözenekli hafif bir yapı oluşturmasıdır. Oluşan bu gözenekli ve hafif yapı per…

Surgery for Submandibular Gland Diseases: 14-years of Experience of a Single Tertiary Center Open

Göksel Turhal, Arın Öztürk, Hakan Ceylan, Serdar Akyıldız, Kerem Öztürk · 2021

Objective: Surgical removal is a valid option in the treatment of submandibular gland diseases but there are still operative and diagnostic pitfalls. We aimed to review and investigate the long-term clinical, surgical, and pathologic outco…

Magnetic soft micromachines made of linked microactuator networks Open

Xinghao Hu, Immihan Ceren Yasa, Ziyu Ren, Sandhya Rani Goudu, Hakan Ceylan , et al. · 2021

The proposed fabrication strategy can enable magnetic soft machines with 2D/3D shape transformations at the cellular scales.

Mattertronics for programmable manipulation and multiplex storage of pseudo-diamagnetic holes and label-free cells Open

Sandhya Rani Goudu, Hyeonseol Kim, Xinghao Hu, Byeonghwa Lim, Kunwoo Kim , et al. · 2021

3D-Printed Multi-Stimuli-Responsive Mobile Micromachines Open

Yun‐Woo Lee, Hakan Ceylan, Immihan Ceren Yasa, Uğur Kılıç, Metin Sitti · 2020

Magnetically actuated and controlled mobile micromachines have the potential to be a key enabler for various wireless lab-on-a-chip manipulations and minimally invasive targeted therapies. However, their embodied, or physical, task executi…

Biodegradable Untethered Magnetic Hydrogel Milli‐Grippers Open

Sandhya Rani Goudu, Immihan Ceren Yasa, Xinghao Hu, Hakan Ceylan, Wenqi Hu , et al. · 2020

Small‐scale magnetic soft‐bodied robots based on biocompatible and biodegradable materials are essential for their potential high‐impact minimally invasive medical applications inside the human body. Therefore, a strategy for fully biodegr…

High‐Yield Production of Biohybrid Microalgae for On‐Demand Cargo Delivery Open

Mukrime Birgul Akolpoglu, Nihal Olcay Dogan, Ugur Bozuyuk, Hakan Ceylan, Seda Kızılel , et al. · 2020

Biohybrid microswimmers exploit the swimming and navigation of a motile microorganism to target and deliver cargo molecules in a wide range of biomedical applications. Medical biohybrid microswimmers suffer from low manufacturing yields, w…

Translational prospects of untethered medical microrobots Open

Hakan Ceylan, Immihan Ceren Yasa, Uğur Kılıç, Wenqi Hu, Metin Sitti · 2019

Untethered mobile microrobots have the potential to transform medicine radically. Their small size and wireless mobility can enable access to and navigation in confined, small, hard-to-reach, and sensitive inner body sites, where they can …

3D-Printed Biodegradable Microswimmer for Theranostic Cargo Delivery and Release Open

Hakan Ceylan, Immihan Ceren Yasa, Öncay Yaşa, Ahmet Fatih Tabak, Joshua Giltinan , et al. · 2019

Untethered mobile microrobots have the potential to leverage minimally invasive theranostic functions precisely and efficiently in hard-to-reach, confined, and delicate inner body sites. However, such a complex task requires an integrated …

New Concepts for 3D Optics in X-ray Microscopy Open

Umut T. Sanli, Hakan Ceylan, Chengge Jiao, Margarita Baluktsian, Corinne Grévent , et al. · 2018

An abstract is not available for this content so a preview has been provided. As you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

3D-Printed Biodegradable Microswimmer for Drug Delivery and Targeted Cell Labeling Open

Hakan Ceylan, Immihan Ceren Yasa, Öncay Yaşa, Ahmet Fatih Tabak, Joshua Giltinan , et al. · 2018

Miniaturization of interventional medical devices can leverage minimally invasive technologies by enabling operational resolution at cellular length scales with high precision and repeatability. Untethered micron-scale mobile robots can re…

3D Nanoprinted Plastic Kinoform X‐Ray Optics Open

Umut T. Sanli, Hakan Ceylan, Iuliia Bykova, Markus Weigand, Metin Sitti , et al. · 2018

High‐performance focusing of X‐rays requires the realization of very challenging 3D geometries with nanoscale features, sub‐millimeter‐scale apertures, and high aspect ratios. A particularly difficult structure is the profile of an ideal z…

Intracellular Accumulation of Gold Nanoparticles Leads to Inhibition of Macropinocytosis to Reduce the Endoplasmic Reticulum Stress Open

Nuray Gündüz, Hakan Ceylan, Mustafa O. Güler, Ayşe B. Tekinay · 2017

Mobile microrobots for bioengineering applications Open

Hakan Ceylan, Joshua Giltinan, Kristen L. Kozielski, Metin Sitti · 2017

Untethered micron-scale mobile robots can navigate and non-invasively perform specific tasks inside unprecedented and hard-to-reach inner human body sites and inside enclosed organ-on-a-chip microfluidic devices with live cells.

WEARABLE GRAPHENE SENSORS ON ADHESIVE TAPES Open

Seval Oren, Shawana Tabassum, Yueyi Jiao, Hakan Ceylan, Muhsin Ali , et al. · 2016

We report a simple, reliable, and cost-effective method of fabricating wearable graphene-based physical sensors on adhesive tapes for detecting mechanical signals, such as pressure, force, and strain.The device fabrication mainly involves …

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