Haley Burrous
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Tissue topography steers migrating <i>Drosophila</i> border cells Open
Cells and the path of least resistance For processes encompassing proper embryonic development, adult homeostasis, tumor cell dissemination, and immunity, certain cells must translocate from their site of origin. Migrating cells navigate p…
Tissue topography steers migrating Drosophila border cells Open
Moving cells can sense and respond to physical features of the microenvironment, however in vivo the significance of tissue topography is mostly unknown. Here we use the Drosophila border cells, an established model for in vivo cell migrat…
Quantitative microscopy of the Drosophila ovary shows multiple niche signals specify progenitor cell fate Open
Adult stem cells commonly give rise to transit-amplifying progenitors, whose progeny differentiate into distinct cell types. It is unclear if stem cell niche signals coordinate fate decisions within the progenitor pool. Here we use quantit…