О.А. Halushko
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View article: Promising methods of treatment of the syndrome of senile fragility: focus on mesenchymal stem cells
Promising methods of treatment of the syndrome of senile fragility: focus on mesenchymal stem cells Open
Senile frailty syndrome (SFS) develops in the elderly and senile as a result of aging-related degeneration and manifests itself in decreased psychological, physiological, and social functioning. Despite decades of research that have led to…
View article: Hyperosmolar hyperglycemic state in elderly and senile patients
Hyperosmolar hyperglycemic state in elderly and senile patients Open
Hyperglycemic hyperosmolar state (HHS) is an acute and life-threatening hyperglycemic emergency that often occurs in elderly and senile patients and leads to significant morbidity and mortality. The aim of this review is to provide up-to-d…
View article: Possibilities of stem cells in the treatment of patients with diabetes
Possibilities of stem cells in the treatment of patients with diabetes Open
BACKGROUND. The group of stem cells includes a heterogeneous group of cells of different origins, united by two key properties: 1) the ability to self-renew through division and 2) the ability to differentiate into mature specialized cell …
View article: Possibilities of stem cells in the treatment of patients with diabetes
Possibilities of stem cells in the treatment of patients with diabetes Open
BACKGROUND. The group of stem cells includes a heterogeneous group of cells of different origins, united by two key properties: 1) the ability to self-renew through division and 2) the ability to differentiate into mature specialized cell …
View article: Diagnostics of pain syndrome in elderly and senile patients
Diagnostics of pain syndrome in elderly and senile patients Open
The prevalence of pain syndrome increases with age, reaching maximum values among elderly people, which is associated with the presence of comorbidities in this cohort of patients. The intensity of pain syndrome and the effect of treatment…
View article: Prospects of alpha-ketoglutaric acid in the treatment of aging and age-related diseases
Prospects of alpha-ketoglutaric acid in the treatment of aging and age-related diseases Open
Alpha-ketoglutaric acid (AKG) has been mentioned as a potential anti-aging agent in recent years. However, there are still not enough pub-lished studies demonstrating the role of AKG in the treatment of aging and age-related diseases. The …
View article: Characteristics of anesthetic management in elderly patients with frailty syndrome
Characteristics of anesthetic management in elderly patients with frailty syndrome Open
The increase in the proportion of elderly people has led to a proportional increase in geriatric patients undergoing surgical treatment. Elderly patients often develop geriatric syndromes, one of which is the frailty syndrome. Aim. Based o…
View article: Polarizing mixture in cardiometabolic diseases: history and prospects
Polarizing mixture in cardiometabolic diseases: history and prospects Open
In 1962, in the American Journal of Cardiology, a group of authors led by D. Sodi-Pallares reported that the use of a mixture of glucose, insulin and potassium – a «polarizing mixture» (PM) in patients with myocardial ischemia is accompani…
View article: Balanced infusion therapy in elderly patients during reconstructive orthopedic operations
Balanced infusion therapy in elderly patients during reconstructive orthopedic operations Open
Background. Reconstructive orthopedic operations — hip and knee arthroplasty (THA) are common surgical interventions in elderly patients and require balanced infusion therapy (InfT). The aim: to determine the effectiveness of balanced infu…
View article: The impact of telomeres on the aging processes in the human body
The impact of telomeres on the aging processes in the human body Open
Telomeres are protective structures located at the ends of chromosomes that regulate cellular aging. Their gradual shortening with each cell division forms the basis of replicative aging and contributes to the development of age-related di…
View article: Postoperative analgesia in elderly patients with frailty syndrome
Postoperative analgesia in elderly patients with frailty syndrome Open
Background. The increase in the proportion of elderly people on the planet has led to a proportional increase in elderly patients undergoing surgical treatment. Elderly surgical patients often develop geriatric syndromes, one of which is t…
View article: Вплив перенесеного COVID-19 на основні чинники кардіоваскулярного ризику в осіб різного віку
Вплив перенесеного COVID-19 на основні чинники кардіоваскулярного ризику в осіб різного віку Open
The aim – to clarify the impact of SARS-CoV-2 on the development of metabolic disorders in middle-aged and elderly people in the period from 1 to 3 months after suffering from the disease of COVID-19.Materials and methods. All of included …
View article: Using glucose-insulin-potassium (GIK) in cardiological patients: history and present
Using glucose-insulin-potassium (GIK) in cardiological patients: history and present Open
In 1962, in the American Journal of Cardiology, a group of authors led by D. Sodi-Pаllares reported that the use of a mixture of glucose, insulin and potassium (GIK) in patients with myocardial ischemia was accompanied by positive changes …
View article: Comparative analysis of the course of the perioperative period in patients with diabetes during knee and hip arthroplasties
Comparative analysis of the course of the perioperative period in patients with diabetes during knee and hip arthroplasties Open
Background. Hip and knee arthroplasty (HKA) are common surgical interventions. In more than 20 % of patients undergoing HKA, diabetes mellitus is detected, which is one of the risk factors for the development of periprosthetic infection an…
View article: Acute coronary syndrome in elderly and senile diabetic patients
Acute coronary syndrome in elderly and senile diabetic patients Open
Acute coronary syndrome (ACS) remains a common cause of hospitalization in diabetes mellitus (DM) patients. It is believed that diabetic neuropathy patients have a high atypical course incidence of acute coronary syndrome, because of the f…
View article: Infusion therapy during knee and hip arthroplasty operations in patients with diabetes
Infusion therapy during knee and hip arthroplasty operations in patients with diabetes Open
BACKGROUND. Hip and knee arthroplasty (HKA) are common surgical interventions that require balanced infusion therapy (IT), especially in patients with concomitant diabetes mellitus (DM). OBJECTIVE. To determine the effectiveness of balance…
View article: Pain syndrome in patients with diabetes after hip and knee endoprosthesis operations
Pain syndrome in patients with diabetes after hip and knee endoprosthesis operations Open
Hip and knee arthroplasty (HKA) are common surgical interventions in patients with diabetes mellitus (DM). An important factor in the postoperative recovery of these patients is the correction of the postoperative pain syndrome. Aim of the…
View article: Development of hypoglycemia in patients with COVID-19: coincidence or the result of treatment?
Development of hypoglycemia in patients with COVID-19: coincidence or the result of treatment? Open
Hypoglycemia is a common complication of diabetes mellitus (DM), which also complicates the course of COVID-19. The aim: The purpose of this work is to analyze the available scientific information on the causes and risk factors of hypoglyc…
View article: Development of hypoglycemia in patients with COVID-19: coincidence or the result of treatment?
Development of hypoglycemia in patients with COVID-19: coincidence or the result of treatment? Open
Hypoglycemia is a common complication of diabetes mellitus (DM), which also complicates the course of COVID-19. The aim: The purpose of this work is to analyze the available scientific information on the causes and risk factors of hypoglyc…
View article: Development and validation of a mathematical model for predicting the development of gastro-oesophageal reflux disease based on oesophagogastroduodenoscopy
Development and validation of a mathematical model for predicting the development of gastro-oesophageal reflux disease based on oesophagogastroduodenoscopy Open
The purpose of this study was to identify a set of prognostic factors for the progression of gastro-oesophageal reflux disease for use in the development of a mathematical model for predicting this disease based on the results of oesophago…
View article: New and little-known possibilities of edaravone in the treatment of cerebral stroke and extracranial pathology
New and little-known possibilities of edaravone in the treatment of cerebral stroke and extracranial pathology Open
BACKGROUND. Edaravone is a free radical scavenger and inhibits lipid peroxidation and thus reduces oxidative damage to brain cells and other organs. Edaravone is mainly known as an effective agent in the treatment of ischemic stroke and am…
View article: Will edaravone become a new complex treatment for diabetes?
Will edaravone become a new complex treatment for diabetes? Open
Edaravone is a low molecular weight antioxidant that scavenges free radicals and inhibits lipid peroxidation, thereby reducing oxidative damage to brain cells and other organs. Edaravone is mainly known as an effective agent in the treatme…
View article: Analysis of clinical series with the use of adjuvants to general anesthesia during elective caesarean section
Analysis of clinical series with the use of adjuvants to general anesthesia during elective caesarean section Open
Background. Caesarean section remains one of the most common surgical interventions in the world. The main disadvantages of the general anesthesia in caesarean section are a high risk of awareness during the operation and a pronounced hemo…
View article: Acute stroke in patients with diabetes mellitus: clinical physiology, diagnosis and course features
Acute stroke in patients with diabetes mellitus: clinical physiology, diagnosis and course features Open
Diabetes mellitus is one of the risk factors for the development of acute stroke. The effects of stress hormones during an acute stroke can exacerbate diabetic ketoacidosis (DKA). There is a significant overlap of symptoms, signs, and labo…
View article: Edaravone in the treatment of concussion and post-concussion syndrome
Edaravone in the treatment of concussion and post-concussion syndrome Open
The review describes the pathogenetic mechanisms of the development of traumatic brain injury (TBI), contusion and post-concussion syndrome, and presents the modern possibilities of their pharmacotherapy. The analysis of experimental and c…
View article: Perinatology and reproductology: from research to practice
Perinatology and reproductology: from research to practice Open
Руслан ТКАЧЕНКОМарина ТРІЩИНСЬКА Сергій ШУРПЯК
View article: Hypoglycemia in patients with COVID-19: risk factors and prevention of complications
Hypoglycemia in patients with COVID-19: risk factors and prevention of complications Open
The aim of the work is to analyze the available scientific information and generalize the main results of modern research on the causes and risk factors of hypoglycemia in patients with COVID-19. Materials and methods. A search and analysi…
View article: HYPOPHOSPHATEMIA AS A COMPLICATION OF THE PERIOPERATIVE PERIOD: CLINICAL PHYSIOLOGY, DIAGNOSIS AND CORRECTION
HYPOPHOSPHATEMIA AS A COMPLICATION OF THE PERIOPERATIVE PERIOD: CLINICAL PHYSIOLOGY, DIAGNOSIS AND CORRECTION Open
Hypophosphatemia (HPE) is one of the frequent electrolyte disorders, for the development of which there are many reasons in the perioperative period. The Medline database was analyzed to identify articles containing hypophosphatemia as one…
View article: HYPOGLYCEMIA IN PATIENTS WITH COVID-19: A COINCIDENCE OR A TREND?
HYPOGLYCEMIA IN PATIENTS WITH COVID-19: A COINCIDENCE OR A TREND? Open
The aim: The purpose of this work is to analyze the available scientific information on causes and risk factors of hypoglycemia during treatment of patients with COVID-19. Materials and methods: A search and analysis of full-text articles …
View article: DIABETES MELLITUS IN THE PRACTICE OF AN ANESTHESIOLOGIST: PERIOPERATIVE MANAGEMENT OF PATIENTS WITH DIABETIC NEUROPATHY
DIABETES MELLITUS IN THE PRACTICE OF AN ANESTHESIOLOGIST: PERIOPERATIVE MANAGEMENT OF PATIENTS WITH DIABETIC NEUROPATHY Open
Diabetic neuropathy (DNP) is a lesion of the nervous system in patients with diabetes mellitus (diabetes), in which all parts of the central, peripheral and autonomic nervous system can be involved in the pathological process. Due to the a…