Hamdullah Sözen
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View article: Predictors and treatment of ısolated recurrence in vulvar cancer confined to the vulva or perineum
Predictors and treatment of ısolated recurrence in vulvar cancer confined to the vulva or perineum Open
Aim: This study evaluated predictors and treatment of isolated vulvar recurrence (IVR) in patients with stage I–II tumors locally confined to the vulva. Methods: We retrospectively collected data from patients with stage I–II vulvar squamo…
View article: An Assessment of the Effectiveness of Preoperative İmaging Modalities (MRI, CT, and 18F-FDG PET/CT) in Determining the Extent of Disease Spread in Epithelial Ovarian–Tubal–Peritoneal Cancer (EOC)
An Assessment of the Effectiveness of Preoperative İmaging Modalities (MRI, CT, and 18F-FDG PET/CT) in Determining the Extent of Disease Spread in Epithelial Ovarian–Tubal–Peritoneal Cancer (EOC) Open
Background and Objectives: Epithelial ovarian–tubal–peritoneal cancer (EOC) is the most common type of ovarian cancer. Optimal cytoreductive surgery is the most important prognostic factor in its management. When complete cytoreduction is …
View article: Sentinel lymph node biopsy with carbon dye in endometrial cancer: a single center, prospective cohort study
Sentinel lymph node biopsy with carbon dye in endometrial cancer: a single center, prospective cohort study Open
Background Many agents have been used for the detection of sentinel lymph nodes in endometrial cancer. Carbon dye, which has a strong staining ability and high contrast due to its dark black color, identifies the lymph nodes efficiently. O…
View article: THE ROLE OF BETA-CATENIN AND FOXP1 IN THE PATHOGENESIS OF POLYPOID ENDOMETRIOSIS
THE ROLE OF BETA-CATENIN AND FOXP1 IN THE PATHOGENESIS OF POLYPOID ENDOMETRIOSIS Open
Objective: To investigate whether beta catenin and Forkhead box protein P1 (FOXP1) play a role in pathogenesis of polypoid endometriosis (PE).Material and Method: Our study included fifteen cases of PE. Clinical findings were gathered from…
View article: #62 MicroRNA 1181 and 4314 as promising biomarkers for epithelial ovarian cancer diagnosis and prognosis
#62 MicroRNA 1181 and 4314 as promising biomarkers for epithelial ovarian cancer diagnosis and prognosis Open
Introduction/Background Epithelial ovarian cancer (EOC) is the most ominous tumor of gynecological cancers due to its poor early detection rate and unfavorable prognosis. To date, there is no reliable screening method for the diagnosis of …
View article: #63 Central nervous system metastasis in gynecologic cancers: seeking the prognostic factors
#63 Central nervous system metastasis in gynecologic cancers: seeking the prognostic factors Open
Introduction/Background Central nervous system (CNS) metastasis originating from gynecological cancer is a rare and late manifestation of the disease. Therefore, there is still limited data on prognostic factors for survival. The objective…
View article: #957 Sentinel lymph node biopsy with carbon dye for endometrial cancer staging: a single center, prospective, cohort study
#957 Sentinel lymph node biopsy with carbon dye for endometrial cancer staging: a single center, prospective, cohort study Open
Introduction/Background Endometrial cancer is the 4th most common cancer in women. Systematic lymphadenectomy determines the disease stage and prognosis. Sentinel lymph node biopsy (SLNB) may be defined as a minimally invasive procedure co…
View article: #104 Risk factors for sentinel lymph node metastasis in endometrial cancer (TRSGO-SLN-010)
#104 Risk factors for sentinel lymph node metastasis in endometrial cancer (TRSGO-SLN-010) Open
Introduction/Background There is limited consensus on the optimal management approach for patients experiencing mapping failure in endometrial cancer (EC). Understanding the risk factors that contribute to sentinel lymph node(SLN) metastas…
View article: Central nervous system metastasis in gynecologic cancers: Seeking the prognostic factors
Central nervous system metastasis in gynecologic cancers: Seeking the prognostic factors Open
S Objective: Central nervous system (CNS) metastasis originating from gynecological cancer is a very rare and late manifestation of the disease. Therefore, there is still limited data on prognostic factors for survival. The objective of th…
View article: Predictors of high-grade residual disease after repeat conization in patients with positive surgical margins
Predictors of high-grade residual disease after repeat conization in patients with positive surgical margins Open
In the cone specimen, the presence of lesion size greater than 5 mm and involvement of the endocervical margin were the predictors of high-grade residual disease after re-excision. Whether it is the first or second procedure, great care mu…
View article: The Etiology of Adnexal Masses in Women with a History of Non-Gynaecologic Malignancy: Recurrence, Second Primary or None?
The Etiology of Adnexal Masses in Women with a History of Non-Gynaecologic Malignancy: Recurrence, Second Primary or None? Open
OBJECTIVE: The new adipokine, neuregulin-4 (NRG-4), acts as a signaling protein and plays a role in lipogenesis, inflammatory events and atherosclerosis. The aim was to investigate maternal levels of NRG-4 in preeclampsia (PE) disease. MAT…
View article: 351 Assessment of HPV infection and p16INK4A and Ki67 expressions in vaginal intraepithelial neoplasia
351 Assessment of HPV infection and p16INK4A and Ki67 expressions in vaginal intraepithelial neoplasia Open
Introduction/Background* The term vaginal intraepithelial neoplasia (VaIN) refers to a premalignant lesion that has the potential to progress to invasive cancer. VaIN is a very rare disease and represents less than 1% of all female genital…
View article: Effect of “Time To Surgery” On The Endometrial Cancer Prognosis
Effect of “Time To Surgery” On The Endometrial Cancer Prognosis Open
OBJECTIVE: Endometrial cancer is the most common gynecological cancer in developed countries. Our study aims to determine the effect of the time between diagnosis and surgery of endometrial cancer on the prognosis of the disease. STUDY DES…
View article: Malignancy Algorithms in The Preoperative Assessment of Suspicious Adnexal Masses During Pregnancy
Malignancy Algorithms in The Preoperative Assessment of Suspicious Adnexal Masses During Pregnancy Open
GİRİŞ ve AMAÇ: Bu çalışmanın amacı,
View article: Effect of Lymphadenectomy on Survival in Early-Stage Type II Endometrial Carcinoma and Carcinosarcoma
Effect of Lymphadenectomy on Survival in Early-Stage Type II Endometrial Carcinoma and Carcinosarcoma Open
Purpose . We aimed to investigate whether systematic pelvic and paraaortic lymph node dissection delivers any survival advantage in a subgroup of patients with type II endometrial carcinoma and carcinosarcoma. Methods . We evaluated 135 pa…
View article: A Retrospective Clinical Analysis Of Hypertermic Intraperitoneal Chemotherapy In Gynecological Cancers: Technıcal Detail, Tolerability And Efficacy
A Retrospective Clinical Analysis Of Hypertermic Intraperitoneal Chemotherapy In Gynecological Cancers: Technıcal Detail, Tolerability And Efficacy Open
CRS+HIPEC procedures had acceptable severe morbidity and mortality rates. In addition, patients with recurrent EOC and without a visible residual disease at the end of cytoreductive surgery had, though not statistically significant, longer…
View article: Comparison of Long-Term Survival Rates of Primary Surgery and Surgery After Neoadjuvant Chemotherapy in Ovarian Cancer
Comparison of Long-Term Survival Rates of Primary Surgery and Surgery After Neoadjuvant Chemotherapy in Ovarian Cancer Open
Introduction:To compare long-term survival of primary debulking surgery (PDS) and interval debulking surgery (IDS) after neoadjuvant chemotherapy (NAC) in patients with advanced ovarian cancer.Methods: Patients who underwent debulking surg…
View article: Comparison of Long-Term Survival Rates of Primary Surgery and Surgery After Neoadjuvant Chemotherapy in Ovarian Cancer
Comparison of Long-Term Survival Rates of Primary Surgery and Surgery After Neoadjuvant Chemotherapy in Ovarian Cancer Open
Introduction:To compare long-term survival of primary debulking surgery (PDS) and interval debulking surgery (IDS) after neoadjuvant chemotherapy (NAC) in patients with advanced ovarian cancer.Methods:Patients who underwent debulking surge…
View article: In patients with advanced ovarian cancer, primary suboptimal surgery has better survival outcome than interval suboptimal surgery
In patients with advanced ovarian cancer, primary suboptimal surgery has better survival outcome than interval suboptimal surgery Open
NAC reduces tumor burden before surgery in advanced ovarian cancer. The prognosis of patients who are not eligible for optimal surgery despite NAC is worse than in patients who do not receive NAC.
View article: Survival Impact of Optimal Surgical Cytoreduction in Recurrent Epithelial Ovarian Cancer with Brain Metastasis
Survival Impact of Optimal Surgical Cytoreduction in Recurrent Epithelial Ovarian Cancer with Brain Metastasis Open
Aim: The aim of this study was to determine the clinicopathological characteristics, treatment details and outcome of patients with brain metastasis from epithelial ovarian carcinoma (EOC). Methods: This study included 21 patients diagnose…
View article: In patients with advanced ovarian cancer, primary suboptimal surgery has better survival outcome than interval suboptimal surgery
In patients with advanced ovarian cancer, primary suboptimal surgery has better survival outcome than interval suboptimal surgery Open
Objective: It is known that optimal or complete cytoreduction is the most important factor in patients with advanced ovarian cancer.The aim of this study was to examine the results of patients who did not undergo optimal cytoreduction and …
View article: Clinicopathologic and survival results in serous endometrium carcinoma and subgroup analysis for mixed serous and pure serous histology
Clinicopathologic and survival results in serous endometrium carcinoma and subgroup analysis for mixed serous and pure serous histology Open
Compared with pure serous and mixed serous endometrium cancer groups, primary surgical treatments, clinicopathologic features and adjuvant treatments were similar, but there was a survival difference. Patients with pure serous cancer had a…
View article: Sentinel Lymph Node Procedures in Gynecological Malignancies
Sentinel Lymph Node Procedures in Gynecological Malignancies Open
Sentinel lymph node (SLN) mapping procedures have been used for many years in malignancies like breast carcinoma and malignant melanoma.For two decades, there has been an effort to use these procedures in gynecological malignancies.Experie…
View article: High expression of SALL4 and fascin, and loss of E-cadherin expression in undifferentiated/dedifferentiated carcinomas of the endometrium
High expression of SALL4 and fascin, and loss of E-cadherin expression in undifferentiated/dedifferentiated carcinomas of the endometrium Open
Undifferentiated/dedifferentiated endometrial carcinomas (UCE/DCEs) of the endometrium are rare tumors with poor prognosis. There are few clinicopathologic studies with detailed immunohistochemical analysis regarding UCE/DCEs.We evaluated …
View article: Evaluation of Neutrophil-Lymphocyte Ratio, Platelet-Lymphocyte Ratio and Red Blood Cell Distribution Width-Platelet Ratio for Diagnosis of Premature Ovarian Insufficiency.
Evaluation of Neutrophil-Lymphocyte Ratio, Platelet-Lymphocyte Ratio and Red Blood Cell Distribution Width-Platelet Ratio for Diagnosis of Premature Ovarian Insufficiency. Open
Objective: To evaluate whether systemic inflammatory markers (neutrophil to lymphocyte ratio (NLR), platelet to lymphocyte ratio (PLR) and red blood cell distribution width (RDW) to platelet ratio (RPR)) can be used as reliable markers for…
View article: Tertiary Cytoreduction for Recurrent Epithelial Ovarian Cancer: a Multicenter Study in Turkey
Tertiary Cytoreduction for Recurrent Epithelial Ovarian Cancer: a Multicenter Study in Turkey Open
Our results and a literature review clearly showed that maximal surgical effort should be made in TC, since patients undergoing optimal TC have a better survival. Thus, patients with secondary recurrent EOC in whom optimal cytoreduction ca…