Hamed Karkehabadi
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View article: In Vitro Antimicrobial Effects of Endoseal MTA and AH Plus Sealers on Enterococcus Faecalis and Candida Albicans Mature Biofilms
In Vitro Antimicrobial Effects of Endoseal MTA and AH Plus Sealers on Enterococcus Faecalis and Candida Albicans Mature Biofilms Open
Objectives: This study compared the antimicrobial effects of Endoseal MTA and AH Plus sealers on Enterococcus faecalis (E. faecalis) and Candida albicans (C. albicans) mature biofilms on dentin blocks. Materials and Methods: In this in vit…
View article: Successful management of a rare two-rooted traumatic maxillary central incisor with severe external root resorption: A case report
Successful management of a rare two-rooted traumatic maxillary central incisor with severe external root resorption: A case report Open
View article: A Novel Approach to Identifying C-Shaped Canals in Mandibular Second Molars by Occlusal Photographs: An Artificial Intelligence Analysis
A Novel Approach to Identifying C-Shaped Canals in Mandibular Second Molars by Occlusal Photographs: An Artificial Intelligence Analysis Open
Objectives: Accurate identification of root canal morphology, particularly C-shaped canals in mandibular second molars, is crucial for successful endodontic treatment. Current diagnostic methods rely on radiographic imaging, which has limi…
View article: Comparative Evaluation of Canal Transport and Centralization Between ProTaper Next and XP‐endo Shaper Systems Using CBCT Analysis: An In Vitro Study
Comparative Evaluation of Canal Transport and Centralization Between ProTaper Next and XP‐endo Shaper Systems Using CBCT Analysis: An In Vitro Study Open
Aim: This study compared the apical transportation and centering ratio of ProTaper Next (PTN) and XP‐endo Shaper (XPS) nickel titanium (NiTi) rotary files in curved root canals using cone beam computed tomography (CBCT). Methodology: The c…
View article: Improvement of the Antimicrobial and Antibiofilm Activity of AH Plus Sealer with Chitosan Nanoparticles and Arginine against Enterococcus faecalis and Candida albicans.
Improvement of the Antimicrobial and Antibiofilm Activity of AH Plus Sealer with Chitosan Nanoparticles and Arginine against Enterococcus faecalis and Candida albicans. Open
The success of endodontic treatments can be significantly impaired by persistent microbial pathogens, especially Enterococcus faecalis (E. faecalis) and Candida albicans (C. albicans)…
View article: Fabrication and characterization of nanocomposite scaffold containing zinc-doped mesoporous bioglass: Evaluation of the antioxidant properties, hemocompatibility and proliferation of apical papilla stem cells
Fabrication and characterization of nanocomposite scaffold containing zinc-doped mesoporous bioglass: Evaluation of the antioxidant properties, hemocompatibility and proliferation of apical papilla stem cells Open
Introduction: Nanocomposite scaffolds comprising mesoporous bioactive glass (MBG) were able to increase the viability, proliferation, and growth of stem cells in vitro, rendering them promising candidates for dental root tissue regeneratio…
View article: Is cone-beam computed tomography more accurate than periapical radiography for detection of vertical root fractures? A systematic review and meta-analysis
Is cone-beam computed tomography more accurate than periapical radiography for detection of vertical root fractures? A systematic review and meta-analysis Open
View article: A Novel Approach for Apical Periodontitis Prevention Through RIPK3 Inhibition Using Organic Flavonoids
A Novel Approach for Apical Periodontitis Prevention Through RIPK3 Inhibition Using Organic Flavonoids Open
Background: Apical periodontitis (AP) entails inflammatory bone resorption facilitated by the induction of necroptosis through receptor-interacting protein kinase 3 (RIPK3). Consequently, the inhibition of RIPK3 holds the potential for fav…
View article: Effects of Final Root Canal Irrigants in Conventional and Regenerative Endodontic Treatments: A Systematic Review
Effects of Final Root Canal Irrigants in Conventional and Regenerative Endodontic Treatments: A Systematic Review Open
Background: The effectiveness of final root canal irrigants is crucial for successful conventional and regenerative endodontic treatments. This study aimed to systematically review the impact of final irrigants on dentin, disinfection, and…
View article: Deep learning for determining the difficulty of endodontic treatment: a pilot study
Deep learning for determining the difficulty of endodontic treatment: a pilot study Open
Background To develop and validate a deep learning model for automated assessment of endodontic case difficulty from periapical radiographs. Methods A dataset of 1,386 periapical radiographs was compiled from two clinical sites. Two dentis…
View article: Correction to: Effects of CEM cement and emdogain on proliferation and differentiation of human stem cells from the apical papilla: a comparative in vitro study
Correction to: Effects of CEM cement and emdogain on proliferation and differentiation of human stem cells from the apical papilla: a comparative in vitro study Open
View article: Association of root morphology of mandibular second molars on panoramic-like and axial views of cone-beam computed tomography
Association of root morphology of mandibular second molars on panoramic-like and axial views of cone-beam computed tomography Open
Background Knowledge about the anatomy and morphology of the root canal system is essential for successful surgical and non-surgical root canal treatments. However, precise assessment of the root morphology and anatomy is not often possibl…
View article: Investigation on the Oxytocin Effect on Proliferation and Osteogenic/Odontogenic Differentiation of Human Stem Cells from the Apical Papilla: An in vitro study
Investigation on the Oxytocin Effect on Proliferation and Osteogenic/Odontogenic Differentiation of Human Stem Cells from the Apical Papilla: An in vitro study Open
Objective This experimental study was conducted with the aim of investigating the effect of oxytocin (OT) on the proliferation and osteo/odontogenic differentiation of human stem cells from the apical papilla (hSCAPs). Material and Methods…
View article: Effect of Low-Level Laser Therapy on Differentiation and Proliferation of Human Dental Pulp Stem Cells: A Systematic Review
Effect of Low-Level Laser Therapy on Differentiation and Proliferation of Human Dental Pulp Stem Cells: A Systematic Review Open
Introduction: Considering the positive impact of laser treatment on the proliferation of certain cell types, we opted to perform a systematic review aimed at evaluating the effects of laser therapy and photobiomodulation on the proliferati…
View article: Structure-Based Virtual Screening of Cinnamic Acid Analogs Against RIPK3: Implications for Anti-Inflammatory Drug Discovery
Structure-Based Virtual Screening of Cinnamic Acid Analogs Against RIPK3: Implications for Anti-Inflammatory Drug Discovery Open
Background: A common oral inflammatory disease known as apical periodontitis (AP) is caused by the intrusion of microorganisms into the dental pulp, resulting in an inflammatory response and bone degradation in periapical tissues. A growin…
View article: The effect of low-dose aspirin on aspirin triggered lipoxin, interleukin 1 beta, and prostaglandin E2 levels in periapical fluid: a double-blind randomized clinical trial
The effect of low-dose aspirin on aspirin triggered lipoxin, interleukin 1 beta, and prostaglandin E2 levels in periapical fluid: a double-blind randomized clinical trial Open
Background The role of pro-resolving mediators in inflammation is a new concern in research. The effect of low-dose aspirin on production of a special kind of these mediators named aspirin triggered lipoxin (ATL) has been studied on differ…
View article: Effect of copper oxide nanoparticles and light-emitting diode irradiation on the cell viability and osteogenic/odontogenic differentiation of human stem cells from the apical papilla
Effect of copper oxide nanoparticles and light-emitting diode irradiation on the cell viability and osteogenic/odontogenic differentiation of human stem cells from the apical papilla Open
Objectives This experimental study aimed to assess the effect of copper oxide nanoparticles (CuONPs) and light-emitting diode (LED) irradiation on the cell viability and osteogenic/odontogenic differentiation of human SCAPs. Methods After …
View article: Investigation of correlation between root morphology of mandibular second molars in panoramic images and cone beam computed tomography
Investigation of correlation between root morphology of mandibular second molars in panoramic images and cone beam computed tomography Open
Background: Knowing the shape of the root and the root canal system is essential for the success of the surgical and non-surgical treatment of the root canal, however; it is difficult to judge root and root canal anatomy from two-dimension…
View article: Combination of Dental Capping Agents With LowLevel Laser Therapy Increases the Cell Viability Percent of Stem Cells From Apical Papilla (SCAPs)
Combination of Dental Capping Agents With LowLevel Laser Therapy Increases the Cell Viability Percent of Stem Cells From Apical Papilla (SCAPs) Open
Introduction: Dental pulp capping is a technique that is highly applicable in dental restorations. In this technique, a material is directly placed over the exposed pulp tissue, which promotes pulp healing and generates reparative dentin. …
View article: Effect of diode low level laser and red light emitting diode irradiation on cell proliferation and osteogenic/odontogenic differentiation of stem cells from the apical papilla
Effect of diode low level laser and red light emitting diode irradiation on cell proliferation and osteogenic/odontogenic differentiation of stem cells from the apical papilla Open
View article: Effect of low-level diode laser and light emitting diode irradiation on cell proliferation and osteogenic/odontogenic differentiation of stem cells from the apical papilla
Effect of low-level diode laser and light emitting diode irradiation on cell proliferation and osteogenic/odontogenic differentiation of stem cells from the apical papilla Open
Background This study aimed to assess the effect of irradiation of light-emitting diode (LED) and low-level diode laser on osteogenic/odontogenic differentiation of stem cells from the apical papilla (SCAPs). Materials and Methods SCAPs we…
View article: Effects of CEM cement and Emdogain on proliferation and differentiation of human stem cells from the apical papilla: A Comparative In Vitro Study
Effects of CEM cement and Emdogain on proliferation and differentiation of human stem cells from the apical papilla: A Comparative In Vitro Study Open
Objectives: This study compared the effects of calcium-enriched mixture (CEM) cement, Emdogain, and their combination (CEM/Emdogain) on differentiation and proliferation of stem cells from the apical papilla (SCAPs). Methods: In this in vi…
View article: Comparative effects of Er:YAG laser, and EDTA, MTAD, and QMix irrigants on adhesion of stem cells from the apical papilla to dentin: A scanning electron microscopic study
Comparative effects of Er:YAG laser, and EDTA, MTAD, and QMix irrigants on adhesion of stem cells from the apical papilla to dentin: A scanning electron microscopic study Open
Despite many favorable properties, MTAD cannot serve as an optimal irrigant in endodontic regenerative procedures since it inhibits the adhesion of SCAPs to dentin and impairs an important step in tissue engineering. Key words:Endod…
View article: Management of Dental School During the COVID-19 Pandemic: Application of Intervention Mapping
Management of Dental School During the COVID-19 Pandemic: Application of Intervention Mapping Open
Background: Coronavirus Diesease-2019 (COVID-19) outbreak has led to the suspension of the activities of dental schools. Therefore, reorganizing clinical settings and supporting services as quickly as possible has received much attention t…
View article: Effect of Biodentine Coated with Emdogain on Proliferation and Differentiation of Stem Cells from the Apical Papilla
Effect of Biodentine Coated with Emdogain on Proliferation and Differentiation of Stem Cells from the Apical Papilla Open
Background: This study assessed the effect of Biodentine coated with Emdogain (Biodentine/Emdogain) on proliferation and differentiation of stem cells from the apical papilla (SCAP). Methods and Results: In this in vitro, experimental stud…
View article: Effect of Cryogenic Treatment on Cyclic Fatigue of Nickel-titanium Rotary Files
Effect of Cryogenic Treatment on Cyclic Fatigue of Nickel-titanium Rotary Files Open
Objective: This study sought to assess the effect of cryogenic treatment on cyclic fatigue of Neoniti and Reciproc nickel-titanium (NiTi) rotary files. This in vitro, experimental study was performed on 48 Neoniti and Reciproc NiTi rotary …
View article: Cone-beam computed tomographic analysis of apical transportation and centering ratio of ProTaper and XP-endo Shaper NiTi rotary systems in curved canals: an in vitro study
Cone-beam computed tomographic analysis of apical transportation and centering ratio of ProTaper and XP-endo Shaper NiTi rotary systems in curved canals: an in vitro study Open
View article: Performance of Bioceramic-based Root Filling Material with Artifact Reduction Properties in the Detection of Vertical Root Fractures Using Cone-beam Computed Tomography
Performance of Bioceramic-based Root Filling Material with Artifact Reduction Properties in the Detection of Vertical Root Fractures Using Cone-beam Computed Tomography Open
Introduction: In Cone-beam Computed Tomography (CBCT) images, metallic artifacts by root filling materials reduce the quality of images. It seems that bioceramic sealers produce fewer artifacts than gutta-percha. In this situation, the pos…
View article: Short-term Effect of Four Root Filling Materials on the Flexural Strength of Human Root Dentin
Short-term Effect of Four Root Filling Materials on the Flexural Strength of Human Root Dentin Open
Background: This study aimed to assess the effects of calcium hydroxide, Biodentine, calcium-enriched mixture (CEM) cement, and mineral trioxide aggregate (MTA) on root dentin flexural strength after a 30-day exposure period. Methods: This…
View article: Cone-Beam Computed Tomographic Analysis of Apical Transportation and Centering Ratio of Protaper and XP-Endo Shaper Niti Rotary Systems in Curved Canals: An in Vitro Study
Cone-Beam Computed Tomographic Analysis of Apical Transportation and Centering Ratio of Protaper and XP-Endo Shaper Niti Rotary Systems in Curved Canals: An in Vitro Study Open
Background: Cleaning and shaping of the root canal system is important in an endodontic treatment. Canal transportation is a common procedural error in preparation of curved canals. This study aimed to compare the canal transportation and …