Hanan Abu-Taha
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View article: Discordant effects of<i>ex-vivo</i>JAK inhibition on inflammatory responses in colonic compared to ileal mucosa
Discordant effects of<i>ex-vivo</i>JAK inhibition on inflammatory responses in colonic compared to ileal mucosa Open
Background & aims Janus kinase (JAK) inhibitors modulating JAK-STAT (signal transducers and activators of transcription) signaling pathway, are used for the treatment of patients with inflammatory bowel diseases (IBD). We aimed to identify…
View article: Human intestinal epithelial cells can internalize luminal fungi via LC3-associated phagocytosis
Human intestinal epithelial cells can internalize luminal fungi via LC3-associated phagocytosis Open
Background Intestinal epithelial cells (IECs) are the first to encounter luminal microorganisms and actively participate in intestinal immunity. We reported that IECs express the β-glucan receptor Dectin-1, and respond to commensal fungi a…
View article: Anti-TNFα Treatment Impairs Long-Term Immune Responses to COVID-19 mRNA Vaccine in Patients with Inflammatory Bowel Diseases
Anti-TNFα Treatment Impairs Long-Term Immune Responses to COVID-19 mRNA Vaccine in Patients with Inflammatory Bowel Diseases Open
Patients with inflammatory bowel disease (IBD) treated with anti-tumor-necrosis factor-alpha (TNFα) exhibited lower serologic responses one-month following the second dose of the COVID-19 BNT162b2 vaccine compared to those not treated with…