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View article: <i>APOE-</i>ε4-induced Fibronectin at the blood-brain barrier is a conserved pathological mediator of disrupted astrocyte-endothelia interaction in Alzheimer’s disease
<i>APOE-</i>ε4-induced Fibronectin at the blood-brain barrier is a conserved pathological mediator of disrupted astrocyte-endothelia interaction in Alzheimer’s disease Open
Blood-brain barrier (BBB) dysfunction is a key feature of Alzheimer’s disease (AD), particularly in individuals carrying the APOE-ε4 allele. This dysfunction worsens neuroinflammation and hinders the removal of toxic proteins, such as amyl…
View article: Cognitive dysfunction in multiple sclerosis patients with hippocampal antibodies
Cognitive dysfunction in multiple sclerosis patients with hippocampal antibodies Open
View article: Kelch-like Protein 11 (KLHL11) Antibodies in Children With Seizures of Undetermined Cause
Kelch-like Protein 11 (KLHL11) Antibodies in Children With Seizures of Undetermined Cause Open
KLHL11-antibody may be detected in pediatric epilepsy patients with a relatively benign disease course.
View article: Investigation of the effects of oxidative stress, inflammation on the pathway of tryptophan/kynurenine in OCD
Investigation of the effects of oxidative stress, inflammation on the pathway of tryptophan/kynurenine in OCD Open
Objectives: Recent studies have shown that the distribution of the tryptophan/kynurenine pathway (KP) plays a role in the development of obsessive-compulsive disorder (OCD). We aimed to reveal the relationship between CYP1A1 rs464903 and a…
View article: Antibody induced seizure susceptibility and impaired cognitive performance in a passive transfer rat model of autoimmune encephalitis
Antibody induced seizure susceptibility and impaired cognitive performance in a passive transfer rat model of autoimmune encephalitis Open
Objective Autoimmune encephalitis (AE) is a distinct neuro-immunological disorder associated with the production of autoantibodies against neuronal proteins responsible for pharmacoresistant seizures, cognitive decline and behavioral probl…
View article: Neuroscience and the Cities: Neurourbanism
Neuroscience and the Cities: Neurourbanism Open
Cities are settlements where many people live together and whose population is constantly growing. Due to the rise of urbanization, the number of buildings in the cities has increased rapidly. The structures in the cities have been designe…
View article: Serum CXCL5 as a biomarker in multiple sclerosis and neuromyelitis optica spectrum disorder
Serum CXCL5 as a biomarker in multiple sclerosis and neuromyelitis optica spectrum disorder Open
Fingolimod might regulate the innate immune system. Serum CXCL5 measurement does not differentiate between RRMS and NMOSD.
View article: The Effect of Lidocaine on the Experimental Model of Streptozotocin-Induced Alzheimer's Disease
The Effect of Lidocaine on the Experimental Model of Streptozotocin-Induced Alzheimer's Disease Open
In addition to neuroprotective effects in STZ-induced AD model, Lidocaine also appears to improve memory. This effect might be associated with increased levels of several growth factors and associated intracellular molecules. The therapeut…
View article: Biomarker value of neurofilaments and glial fibrillary acidic protein in central nervous system lymphoma and tumors
Biomarker value of neurofilaments and glial fibrillary acidic protein in central nervous system lymphoma and tumors Open
View article: Cerebrospinal Fluid Level of Phosphorylated Neurofilament Heavy Chain is Higher in Converting Clinically Isolated Syndrome and Correlates with CAMP Response Element-Binding Protein Concentration
Cerebrospinal Fluid Level of Phosphorylated Neurofilament Heavy Chain is Higher in Converting Clinically Isolated Syndrome and Correlates with CAMP Response Element-Binding Protein Concentration Open
Introduction: Prevision of conversion from clinically isolated syndrome (CIS) to multiple sclerosis (MS) is required to avoid unnecessary use of immunomodulating agents and to recognize patients with high disease activity. Our aim was to e…
View article: Expression Levels of B Cell Receptor (BCR) Signaling Pathway Factors are Associated with Conversion from Clinically Isolated Syndrome to Multiple Sclerosis
Expression Levels of B Cell Receptor (BCR) Signaling Pathway Factors are Associated with Conversion from Clinically Isolated Syndrome to Multiple Sclerosis Open
Objective: We have previously shown altered blood B cells in the first attack blood samples of clinically isolated syndrome (CIS) pa-tients, who converted to multiple sclerosis (MS). Our aim was to investigate levels of B cell receptor (BC…
View article: Serum levels of inflammasome pathway factors in clinically isolated syndrome and multiple sclerosis patients: a pilot study
Serum levels of inflammasome pathway factors in clinically isolated syndrome and multiple sclerosis patients: a pilot study Open
Pathogenic roles of nuclear factor κB (NF-κB) pathway and NLRP3 inflammasome complex factors are involved in multiple sclerosis (MS) development. Activation of the NF-κB, NLRP3, and caspase-1 cascade results in production of proinflammator…
View article: Insomnia and Dysautonomia with Contactin-Associated Protein 2 and Leucine-Rich Glioma Inactivated Protein 1 Antibodies: A “Forme Fruste” of Morvan Syndrome?
Insomnia and Dysautonomia with Contactin-Associated Protein 2 and Leucine-Rich Glioma Inactivated Protein 1 Antibodies: A “Forme Fruste” of Morvan Syndrome? Open
Morvan syndrome (MoS) is typically characterized by neuromyotonia, sleep dysfunction, dysautonomia, and cognitive dysfunction. However, MoS patients with mild peripheral nerve hyperexcitability (PNH) or encephalopathy features have been de…