Handong Xu
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View article: A paradigm shift in DENV-4 clinical presentation: A viewpoint on pulmonary inflammatory symptoms from the 2023 Lincang outbreak
A paradigm shift in DENV-4 clinical presentation: A viewpoint on pulmonary inflammatory symptoms from the 2023 Lincang outbreak Open
Background During the 2023 outbreak of dengue virus serotype 4 (DENV-4) in Lincang, China, we noted prominent lower-respiratory involvement not typically emphasized in dengue descriptions. Methods We retrospectively analyzed 147 hospitaliz…
View article: Analysis of kinematic factors influencing performance in the Chinese men’s 4 × 100 m relay team
Analysis of kinematic factors influencing performance in the Chinese men’s 4 × 100 m relay team Open
View article: Submaximal loading as a feasible alternative to supramaximal loading in accentuated eccentric loading during the short-term basic strength block
Submaximal loading as a feasible alternative to supramaximal loading in accentuated eccentric loading during the short-term basic strength block Open
Purpose The purpose of this study was to compare the effects of supramaximal and submaximal accentuated eccentric loading (AEL) on lower-body function and hypertrophy during a short-term basic strength block. Methods Twenty-two trained mal…
View article: Reinforcement Learning with Rubric Anchors
Reinforcement Learning with Rubric Anchors Open
Reinforcement Learning from Verifiable Rewards (RLVR) has emerged as a powerful paradigm for enhancing Large Language Models (LLMs), exemplified by the success of OpenAI's o-series. In RLVR, rewards are derived from verifiable signals-such…
View article: Unsupervised detection of rare events in liquid biopsy assays
Unsupervised detection of rare events in liquid biopsy assays Open
View article: H-mode characteristics and first experimental results of current drive with electron cyclotron waves on EAST
H-mode characteristics and first experimental results of current drive with electron cyclotron waves on EAST Open
Reproducible H-mode plasmas with electron cyclotron (EC) waves as the sole auxiliary heating tool have been achieved recently on EAST in a broad range of plasma parameters with an ITER-like tungsten divertor. The macroscopic characteristic…
View article: Modeling study of synergistic effects between lower hybrid and electron cyclotron current drive on EAST
Modeling study of synergistic effects between lower hybrid and electron cyclotron current drive on EAST Open
Recent radio frequency (RF) current drive experiments in EAST provide an opportunity to investigate RF synergy effects between electron cyclotron (EC) and lower hybrid (LH) current drive. Synergy current is the excess current that can aris…
View article: Unsupervised Detection of Rare Events in Liquid Biopsy Assays
Unsupervised Detection of Rare Events in Liquid Biopsy Assays Open
The use of liquid biopsies in the detection, diagnosis and treatment monitoring of different types of cancers and other diseases often requires identifying and enumerating instances of analytes that are rare. Most current techniques that a…
View article: TableGPT2: A Large Multimodal Model with Tabular Data Integration
TableGPT2: A Large Multimodal Model with Tabular Data Integration Open
The emergence of models like GPTs, Claude, LLaMA, and Qwen has reshaped AI applications, presenting vast new opportunities across industries. Yet, the integration of tabular data remains notably underdeveloped, despite its foundational rol…
View article: ECW assisted plasma startup with low toroidal electric field and full metal wall in EAST superconducting tokamak
ECW assisted plasma startup with low toroidal electric field and full metal wall in EAST superconducting tokamak Open
Recent experimental results from the EAST superconducting tokamak with a full metal wall (without Li-coating) provide strong support for the ITER startup scheme with electron cyclotron wave (ECW) assistance. Detailed investigations were pe…
View article: I-mode plasma confinement improvement by real-time lithium injection and its classification on EAST tokamak
I-mode plasma confinement improvement by real-time lithium injection and its classification on EAST tokamak Open
I-mode is a promising regime for future fusion reactors due to the high energy confinement and the moderate particle confinement. However, the effect of lithium, which has been widely applied for particle recycling and impurity control, on…
View article: Neoclassical tearing mode stabilization by electron cyclotron current drive in EAST tokamak experiments
Neoclassical tearing mode stabilization by electron cyclotron current drive in EAST tokamak experiments Open
The stabilization of the m / n = 2/1 neoclassical tearing mode (NTM) by electron cyclotron current drive (ECCD) has been carried out in EAST H-mode discharges, where m / n is the poloidal/toroidal mode number. The experimental results are …
View article: Experimental research of ECW pre-ionization and assisted startup in EAST
Experimental research of ECW pre-ionization and assisted startup in EAST Open
Experimental research on the electron cyclotron wave (ECW) pre-ionization and assisted start-up was carried out systematically for the first time in EAST tokamak, which is a superconducting device with ITER-like full metal wall. Breakdown …
View article: I-mode Plasma Confinement Improvement by Real-time Lithium Injection and its Classification on EAST Tokamak
I-mode Plasma Confinement Improvement by Real-time Lithium Injection and its Classification on EAST Tokamak Open
I-mode is a promising regime for future fusion reactors due to the high energy confinement and the moderate particle confinement. However, the effect of lithium, which has been widely applied for particle recycling and impurity control, on…
View article: Long-pulse high-performance H-mode plasmas achieved on EAST
Long-pulse high-performance H-mode plasmas achieved on EAST Open
A record duration of a 310 s H-mode plasma (H98y2 ∼ 1.3, ne/nGW ∼ 0.7, fBS > 50%) has been recently achieved on experimental advanced superconducting tokamak (EAST) with metal walls, exploiting the device's improved long-pulse capabilit…
View article: Glutathione peroxidase 2 knockdown suppresses gastric cancer progression and metastasis via regulation of kynurenine metabolism
Glutathione peroxidase 2 knockdown suppresses gastric cancer progression and metastasis via regulation of kynurenine metabolism Open
Gastric cancer (GC) is among the most lethal malignancies due to its poor early diagnosis and high metastasis rate, and new therapeutic targets are urgently needed to develop effective anti-GC drugs. Glutathione peroxidase-2 (GPx2) plays v…
View article: All superconducting tokamak: EAST
All superconducting tokamak: EAST Open
Experimental Advanced Superconducting Tokamak (EAST) was built to demonstrate high-power, long-pulse operations under fusion-relevant conditions, with major radius R = 1.9 m, minor radius a = 0.5 m, and design pulse length up to 1000s. It …
View article: Realization of thousand-second improved confinement plasma with Super I-mode in Tokamak EAST
Realization of thousand-second improved confinement plasma with Super I-mode in Tokamak EAST Open
Mastering nuclear fusion, which is an abundant, safe, and environmentally competitive energy, is a great challenge for humanity. Tokamak represents one of the most promising paths toward controlled fusion. Obtaining a high-performance, ste…
View article: Simulation of Current Density Profile for East Advanced Scenario with Metis Code
Simulation of Current Density Profile for East Advanced Scenario with Metis Code Open
View article: Plasma heating and improvement of lower hybrid current drive efficiency by electron cyclotron waves on EAST
Plasma heating and improvement of lower hybrid current drive efficiency by electron cyclotron waves on EAST Open
The electron cyclotron (EC) system on EAST consists of four gyrotrons with a frequency of 140 GHz (second harmonic of the extraordinary mode), each of which is expected to deliver a maximum power of 1.0 MW and be operated at 100-1000 s pul…
View article: Gyrotron anode voltage control in EAST ECRH system
Gyrotron anode voltage control in EAST ECRH system Open
Four diode-type gyrotrons are used in the EAST ECRH system now. The anode is one of the main components of the gyrotron. We can control the output power of the gyrotron by changing the anode voltage. An anode voltage control system for ASI…
View article: Realization of T <sub>e0</sub> > 10 keV long pulse operation over 100 s on EAST
Realization of T <sub>e0</sub> > 10 keV long pulse operation over 100 s on EAST Open
In 2021, EAST realized a steady-state long pulse with a duration over 100 s and a core electron temperature over 10 keV. This is an integrated operation that resolves several key issues, including active control of wall conditioning, long-…
View article: Visualized radio-clinical biomarker for predicting neoadjuvant chemotherapy response and prognosis from pretreatment oversampled CT images of LAGC patients: A multicenter study
Visualized radio-clinical biomarker for predicting neoadjuvant chemotherapy response and prognosis from pretreatment oversampled CT images of LAGC patients: A multicenter study Open
Background : The early noninvasive screening of patients suitable for neoadjuvant chemotherapy (NCT) is essential for personalized treatment in locally advanced gastric cancer (LAGC). The aim of this study was to develop and visualized a r…
View article: Huaier Inhibits Gastric Cancer Growth and Hepatic Metastasis by Reducing Syntenin Expression and STAT3 Phosphorylation
Huaier Inhibits Gastric Cancer Growth and Hepatic Metastasis by Reducing Syntenin Expression and STAT3 Phosphorylation Open
Gastric cancer (GC) is a common malignant tumor worldwide and poses a serious threat to human health. As a traditional Chinese medicine, Huaier (Trametes robiniophila Murr.) has been used in the clinical treatment of GC. However, the mecha…
View article: Trametes robiniophila Murr Sensitizes Gastric Cancer Cells to 5-Fluorouracil by Modulating Tumor Microenvironment
Trametes robiniophila Murr Sensitizes Gastric Cancer Cells to 5-Fluorouracil by Modulating Tumor Microenvironment Open
Trametes robiniophila Murr (TRM) is a traditional Chinese medicine which has been used in clinics for enhancing immunity and improving the efficacy of chemotherapy. However, the mechanisms of action of TRM are unknown. In the previous stud…
View article: First Identification of New X-Ray Spectra of Mo39+, Mo40+, W43+, W44+ and W45+ on EAST
First Identification of New X-Ray Spectra of Mo39+, Mo40+, W43+, W44+ and W45+ on EAST Open
New high-resolution x-ray spectra of Mo39+, Mo40+, W43+, W44+ and W45+ have been carefully confirmed for the first time by use of the x-ray imaging crystal spectrometer (XCS) in Experimental Advanced Superconducting Tokamak (EAST) under va…
View article: EAST steady-state long pulse H-mode with core-edge integration for CFETR
EAST steady-state long pulse H-mode with core-edge integration for CFETR Open
A recent EAST experiment has successfully demonstrated long pulse steady-state high plasma performance scenario and core-edge integration since the last IAEA in 2018. A discharge with a duration over 60 s with β P ∼ 2.0, β N ∼ 1.6, H 98y2 …
View article: The Role of Autophagy in Gastric Cancer Chemoresistance: Friend or Foe?
The Role of Autophagy in Gastric Cancer Chemoresistance: Friend or Foe? Open
Gastric cancer is the third most common cause of cancer-related death worldwide. Drug resistance is the main inevitable and vital factor leading to a low 5-year survival rate for patients with gastric cancer. Autophagy, as a highly conserv…
View article: Stress analysis and design of the waveguide bellows for EAST ECRH system
Stress analysis and design of the waveguide bellows for EAST ECRH system Open
A 140GHz 4MW long pulse ECRH system for the experimental advanced superconducting tokamak (EAST) has launched in 2011. The waveguide (WG) bellows is an important component in transmission lines, which can absorbs the axial deformation caus…
View article: Control of the gyrotron filament power supplies for the experimental advanced superconducting tokamak
Control of the gyrotron filament power supplies for the experimental advanced superconducting tokamak Open
The electron cyclotron heating system including four gyrotrons is being developed in the Institute of Plasma Physics, Chinese Academy of Sciences. The filament is an important part of the gyrotron, which is used to heat the cathode. The gy…