Haneur Lee
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View article: Rapid and Accurate Ecotoxicological Assessment of Heavy Metals Using Cyprinus carpio Cells
Rapid and Accurate Ecotoxicological Assessment of Heavy Metals Using Cyprinus carpio Cells Open
Heavy metals have serious negative effects on various aquatic organisms, and therefore rapid and accurate ecotoxicological assessments of heavy metals are necessary. Fish-derived cells sensitive to heavy metals have been used as valuable t…
View article: Rapid ecotoxicological assessment using Cyprinus carpio cell lines
Rapid ecotoxicological assessment using Cyprinus carpio cell lines Open
Fish are known for their exceptional sensitivity and rapid physiological responses to environmental pollutants, making them a valuable tool for ecotoxicological assessment. However, the complex sensitivity of fish to a variety of stressors…
View article: Targeting Mitochondrial Oxidative Stress as a Strategy to Treat Aging and Age-Related Diseases
Targeting Mitochondrial Oxidative Stress as a Strategy to Treat Aging and Age-Related Diseases Open
Mitochondria are one of the organelles undergoing rapid alteration during the senescence process. Senescent cells show an increase in mitochondrial size, which is attributed to the accumulation of defective mitochondria, which causes mitoc…
View article: Functional restoration of lysosomes and mitochondria through modulation of AKT activity ameliorates senescence
Functional restoration of lysosomes and mitochondria through modulation of AKT activity ameliorates senescence Open
Senescence is a phenomenon defined by alterations in cellular organelles and is the primary cause of aging and aging-related diseases. Recent studies have shown that oncogene-induced senescence is driven by activation of serine/threonine p…
View article: Chemical screening identifies the anticancer properties of <i>Polyporous tuberaster</i>
Chemical screening identifies the anticancer properties of <i>Polyporous tuberaster</i> Open
Most conventional anticancer drugs cause resistance to chemotherapy, which has emerged as one of the major obstacles to cancer treatment. In order to address this issue, efforts have been made to select new anticancer compounds from natura…
View article: Chemical screening identifies the anticancer properties of <i>Polyporous parvovarius</i>
Chemical screening identifies the anticancer properties of <i>Polyporous parvovarius</i> Open
One of the biggest obstacles in cancer treatment is the development of chemoresistance. To overcome this, attempts have been made to screen novel anticancer substances derived from natural products. The purpose of this study is to find new…
View article: Metabolic reprogramming as a novel therapeutic target for Coxsackievirus B3
Metabolic reprogramming as a novel therapeutic target for Coxsackievirus B3 Open
Coxsackievirus B3 (CVB3) is a single-stranded RNA virus that belongs to the Enterovirus genus. CVB3 is a human pathogen associated with serious conditions such as myocarditis, dilated cardiomyopathy, and pancreatitis. However, there…
View article: Targeting regulation of ATP synthase 5 alpha/beta dimerization alleviates senescence
Targeting regulation of ATP synthase 5 alpha/beta dimerization alleviates senescence Open
Senescence is a distinct set of changes in the senescence-associated secretory phenotype (SASP) and leads to aging and age-related diseases. Here, we screened compounds that could ameliorate senescence and identified an oxazoloquinoline an…
View article: Metabolic Reprogramming as a Novel Therapeutic Target for Coxsackievirus B3
Metabolic Reprogramming as a Novel Therapeutic Target for Coxsackievirus B3 Open
View article: Targeting Mitochondrial Metabolism as a Strategy to Treat Senescence
Targeting Mitochondrial Metabolism as a Strategy to Treat Senescence Open
Mitochondria are one of organelles that undergo significant changes associated with senescence. An increase in mitochondrial size is observed in senescent cells, and this increase is ascribed to the accumulation of dysfunctional mitochondr…