Explanipedia

Supplementary Table S2 from Caffeine Supplementation and FOXM1 Inhibition Enhance the Antitumor Effect of Statins in Neuroblastoma Open

Gia‐Buu Tran, Jane Ding, Bingwei Ye, Mengling Liu, Yunhong Zha , et al. · 2025

Simvastatin responsive genes

Table S3 from Caffeine Supplementation and FOXM1 Inhibition Enhance the Antitumor Effect of Statins in Neuroblastoma Open

Gia‐Buu Tran, Jane Ding, Bingwei Ye, Mengling Liu, Yajie Yu , et al. · 2025

GO analysis of genes down-regulated by simvastatin

Supplementary Table S1 from Caffeine Supplementation and FOXM1 Inhibition Enhance the Antitumor Effect of Statins in Neuroblastoma Open

Jane Ding, Mengling Liu, Yajie Yu, Yunhong Zha, Kebin Liu , et al. · 2025

qRT-PCR primers

Table S4 from Caffeine Supplementation and FOXM1 Inhibition Enhance the Antitumor Effect of Statins in Neuroblastoma Open

Jane Ding, Bingwei Ye, Mengling Liu, Zheng Dong, Sunil Sudarshan , et al. · 2025

GO analysis of genes up-regulated in the Simvastatin plus mevalonate group vs. the simvastatin group.

Table S5 from Caffeine Supplementation and FOXM1 Inhibition Enhance the Antitumor Effect of Statins in Neuroblastoma Open

Jane Ding, Bingwei Ye, Mengling Liu, Yunhong Zha, Zheng Dong , et al. · 2025

Go analysis of genes up-regulated by simvastatin

Genome-wide association study for mapping QTLs and candidate gene analysis of rice chalkiness Open

Liang Chen, Xiaoming Li, Qi Zhong, Annelii Ny, Xulong Zhu , et al. · 2025

DKC1-mediated pseudouridylation of rRNA targets hnRNP A1 to sustain IRES-dependent translation and ATF4-driven metabolic adaptation Open

Anamika Gupta, Mohit Bansal, Jane Ding, Suman Karki, Madhuparna Pandit , et al. · 2025

The pseudouridine synthase DKC1 regulates internal ribosome entry site (IRES)–dependent translation and is up-regulated in cancers by the MYC family of oncogenes. The functional significance of DKC1 up-regulation and the mechanistic connec…

The mevalonate pathway couples lipid metabolism to amino acid synthesis via ubiquinone-dependent redox control Open

Thi Thinh Nguyen, Mohit Bansal, Jane Ding, Sunil Sudarshan, Han‐Fei Ding · 2025

The mevalonate pathway produces sterols and isoprenoids that support cancer cell growth, yet its broader metabolic functions remain incompletely defined. Here, we show that this pathway sustains amino acid biosynthesis by promoting mitocho…

An AI‐Enabled All‐In‐One Visual, Proximity, and Tactile Perception Multimodal Sensor Open

Menghao Pu, T. Zhao, Lingxi Zhang, Chaoqun Han, Zhiping Chai , et al. · 2025

Interactive robotic tasks heavily rely on comprehensive environment perception. Particularly, visual, proximity, and tactile perception are essential sensing modalities providing comprehensive information in such scenarios. However, integr…

HDAC7 promotes renal cancer progression by reprogramming branched-chain amino acid metabolism Open

Hyeyoung Nam, Anirban Kundu, Suman Karki, Richard Kirkman, Darshan S. Chandrashekar , et al. · 2025

Clear cell renal cell carcinoma (ccRCC), the most common subtype of kidney cancer, exhibits notable metabolic reprogramming. We previously reported elevated HDAC7, a class II histone deacetylase, in ccRCC. Here, we demonstrate that HDAC7 p…

Editorial Expression of Concern: Epithelial–mesenchymal transition of ovarian cancer cells is sustained by Rac1 through simultaneous activation of MEK1/2 and Src signaling pathways Open

Dong Fang, Honglei Chen, Jinyong Zhu, Wei Wang, Yong Teng , et al. · 2025

Disturbance Estimation of Legged Robots: Predefined Convergence via Dynamic Gains Open

Bolin Li, Peiyuan Cai, Gewei Zuo, Lijun Zhu, Han‐Fei Ding · 2025

In this study, we address the challenge of disturbance estimation in legged robots by introducing a novel continuous-time online feedback-based disturbance observer that leverages measurable variables. The distinct feature of our observer …

DKC1-mediated pseudouridylation of rRNA targets hnRNP A1 to sustain IRES-dependent translation and ATF4-driven metabolic adaptation Open

Anamika Gupta, Mohit Bansal, Jane Ding, Madhuparna Pandit, Sunil Sudarshan , et al. · 2024

The pseudouridine synthase DKC1 regulates internal ribosome entry site (IRES)-dependent translation and is upregulated in cancers by the MYC family of oncogenic transcription factors. We investigated the functional significance of DKC1 in …

Novel carbon dots with dual Modulatory effects on the bone marrow and spleen as a potential therapeutic candidate for treating spinal cord injury Open

Junjin Li, Hongda Wang, Yiyi Li, Chunzhen Wang, Haiwen Feng , et al. · 2024

Data from MYC Drives mRNA Pseudouridylation to Mitigate Proliferation-Induced Cellular Stress during Cancer Development Open

Jane Ding, Mohit Bansal, Yuxia Cao, Bingwei Ye, Rui Mao , et al. · 2024

Pseudouridylation is a common RNA modification that is catalyzed by the family of pseudouridine synthases (PUS). Pseudouridylation can increase RNA stability and rigidity, thereby impacting RNA splicing, processing, and translation. Given …

Supplementary Data from MYC Drives mRNA Pseudouridylation to Mitigate Proliferation-Induced Cellular Stress during Cancer Development Open

Jane Ding, Mohit Bansal, Yuxia Cao, Bingwei Ye, Rui Mao , et al. · 2024

Figure S1. PUS7 is a direct transcriptional target of MYC oncoproteins. Figure S2. High PUS7 expression is associated with poor prognosis and is required for the proliferation and tumorigenicity MYC-driven cancer cells. Figure S3. Function…

Supplementary Tables from MYC Drives mRNA Pseudouridylation to Mitigate Proliferation-Induced Cellular Stress during Cancer Development Open

Jane Ding, Mohit Bansal, Yuxia Cao, Bingwei Ye, Rui Mao , et al. · 2024

Table S1. primers and oligonucleotides. Table S2. Microarray gene expression profiling (shPUS7-33 vs shGFP). Table S3. Functional annotation of PUS7 knockdown-responsive genes. Table S4. 13C-glucose metabolic flux analysis. Table S5. 13C-1…

Arsenic trioxide versus Realgar-Indigo naturalis formula in non-high-risk acute promyelocytic leukemia: a multicenter, randomized trial Open

Shu Chen, Weiwei Qin, Xiaohong Lü, Li Liu, Yin-Suo Zheng , et al. · 2024

Realgar-Indigo Naturalis Formula (RIF) is an oral form of arsenic that is effective against acute promyelocytic leukemia (APL). This multicenter, randomized, controlled trial compared the efficacy of all-trans retinoic acid (ATRA) plus RIF…

Leveraging Surgical Activity Grammar for Primary Intention Prediction in Laparoscopy Procedures Open

Jie Zhang, Song Zhou, Yiwei Wang, Chidan Wan, Huan Zhao , et al. · 2024

Surgical procedures are inherently complex and dynamic, with intricate dependencies and various execution paths. Accurate identification of the intentions behind critical actions, referred to as Primary Intentions (PIs), is crucial to unde…

Supplementary Table S1 from Caffeine supplementation and FOXM1 inhibition enhance the antitumor effect of statins in neuroblastoma Open