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View article: Metabolomics analysis identifies hypoxia-induced ferroptosis in the liver of silver carp (Hypophthalmichthys molitrix)
Metabolomics analysis identifies hypoxia-induced ferroptosis in the liver of silver carp (Hypophthalmichthys molitrix) Open
View article: Competitive Bio-Accumulation Between Ammonia and Nitrite Results in Their Antagonistic Toxicity to Hypophthalmichthys molitrix: Antioxidant and Immune Responses and Metabolic Detoxification Evidence
Competitive Bio-Accumulation Between Ammonia and Nitrite Results in Their Antagonistic Toxicity to Hypophthalmichthys molitrix: Antioxidant and Immune Responses and Metabolic Detoxification Evidence Open
Ammonia and nitrite, as major aquatic pollutants, exhibit significant toxicity toward aquatic organisms. However, their interactive effects on fish are unclear. Aiming to determine their interactive effects, silver carp (Hypophthalmichthys…
View article: Chromosome-scale genome assembly and annotation of Xenocypris argentea
Chromosome-scale genome assembly and annotation of Xenocypris argentea Open
View article: A 5′ Promoter Region SNP in CTSC Leads to Increased Hypoxia Tolerance in Changfeng Silver Carp (Hypophthalmichthys molitrix)
A 5′ Promoter Region SNP in CTSC Leads to Increased Hypoxia Tolerance in Changfeng Silver Carp (Hypophthalmichthys molitrix) Open
Silver carp is a critically significant species in freshwater aquaculture in China, characterized by its limited tolerance to hypoxia. In this study, a significant SNP locus at Chr8: 29647765 (T/C) associated with hypoxia tolerance traits …
View article: Effects of Different Carbohydrate Levels in Diets on Growth Performance and Muscle Nutritive Value of Ying Carp and Scattered‐Scaled Mirror Carp (<i>Cyprinus carpio</i>)
Effects of Different Carbohydrate Levels in Diets on Growth Performance and Muscle Nutritive Value of Ying Carp and Scattered‐Scaled Mirror Carp (<i>Cyprinus carpio</i>) Open
This experiment aimed to assess the dietary adaptation and utilization of high carbohydrate diets to Ying carp and scattered‐scaled mirror carp ( Cyprinus carpio ), focusing on growth performance, muscle nutritive value, and nutrient metab…
View article: Targeting and editing the second exon of bmp6 gene results in a silver carp with reduced intramuscular bones
Targeting and editing the second exon of bmp6 gene results in a silver carp with reduced intramuscular bones Open
Intermuscular bones (IBs) are needle-like bones frequently observed within the muscle septa of cyprinid fish, which adversely affects fish palatability and economic value. The deletion of bmp6 has been shown to lead the absence of IBs in f…
View article: Chromosome-level genome assembly of Plagiognathops microlepis based on PacBio HiFi and Hi-C sequencing
Chromosome-level genome assembly of Plagiognathops microlepis based on PacBio HiFi and Hi-C sequencing Open
View article: Transcriptome Analysis Reveals the Potential Key Genes in Nutritional Deposition in the Common Carp (Cyprinus carpio)
Transcriptome Analysis Reveals the Potential Key Genes in Nutritional Deposition in the Common Carp (Cyprinus carpio) Open
The common carp (Cyprinus carpio) is one of the most important aquaculture species in China, known for its remarkable adaptability and nutritional profile. However, the specific molecular response mechanisms regulating the nutritional depo…
View article: Transcriptome Analysis Elucidates the Potential Key Genes Involved in Rib Development in bmp6-Deficient Silver Carp (Hypophthalmichthys molitrix)
Transcriptome Analysis Elucidates the Potential Key Genes Involved in Rib Development in bmp6-Deficient Silver Carp (Hypophthalmichthys molitrix) Open
Bone morphogenetic protein 6 (BMP-6) is a constituent of the TGF-β superfamily, known for its ability to stimulate bone and cartilage formation. The investigation of bmp6’s involvement in the formation of intermuscular bones in fish has ga…
View article: Genetic diversity and population structure analysis of blunt snout bream (Megalobrama amblycephala) in the Yangtze River Basin: Implications for conservation and utilization
Genetic diversity and population structure analysis of blunt snout bream (Megalobrama amblycephala) in the Yangtze River Basin: Implications for conservation and utilization Open
The blunt snout bream, Megalobrama amblycephala, is a commercially significant freshwater fish species indigenous to China. In recent decades, fishery resources of blunt snout bream in the Yangtze River have been severely depleted owing to…
View article: Genetic Diversity and Population Structure of Eight Cultured <i>Hypophthalmichthys molitrix</i> in Hubei Province, China, Inferred from Mitochondrial COI Gene
Genetic Diversity and Population Structure of Eight Cultured <i>Hypophthalmichthys molitrix</i> in Hubei Province, China, Inferred from Mitochondrial COI Gene Open
Silver carp’s ( Hypophthalmichthys molitrix ) traits and genetic structure are being impacted by artificial proliferation and restocking enhancement. A clear genetic background of cultured silver carp is helpful for exploitation and utiliz…
View article: A Time-Dependent Interactive Effect of Nitrite and Ammonia on Inflammatory and Immune Response in the Head Kidney of Silver Carp (Hypophthalmichthys Molitrix)
A Time-Dependent Interactive Effect of Nitrite and Ammonia on Inflammatory and Immune Response in the Head Kidney of Silver Carp (Hypophthalmichthys Molitrix) Open
View article: Identification and characterization of ABCC gene family and their roles in the response to intraperitoneal injection of microcystin-LR in liver of silver carp (Hypophthalmichthys molitrix)
Identification and characterization of ABCC gene family and their roles in the response to intraperitoneal injection of microcystin-LR in liver of silver carp (Hypophthalmichthys molitrix) Open
Silver carp (Hypophthalmichthys molitrix) is a widely distributed food resource and phytoplankton predator in China, which has been used to control algal blooms. Silver carp is quite resistant to microcystins (MCs), which are typical hepat…
View article: Mercury Induced Tissue Damage, Redox Metabolism, Ion Transport, Apoptosis, and Intestinal Microbiota Change in Red Swamp Crayfish (Procambarus clarkii): Application of Multi-Omics Analysis in Risk Assessment of Hg
Mercury Induced Tissue Damage, Redox Metabolism, Ion Transport, Apoptosis, and Intestinal Microbiota Change in Red Swamp Crayfish (Procambarus clarkii): Application of Multi-Omics Analysis in Risk Assessment of Hg Open
As one of the most toxic elements, mercury (Hg) is a widespread toxicant in aquatic environments. Crayfish are considered suitable for indicating the impact of heavy metals on aquatic crustaceans. Nevertheless, Hg toxicity on Procambarus c…
View article: Microsatellite Characteristics of Silver Carp (Hypophthalmichthysmolitrix) Genome and Genetic Diversity Analysis in Four Cultured Populations
Microsatellite Characteristics of Silver Carp (Hypophthalmichthysmolitrix) Genome and Genetic Diversity Analysis in Four Cultured Populations Open
Hypophthalmichthys molitrix is one of the four most important fish in China and has high breeding potential. However, simple sequence repeat (SSR) markers developed on H. molitrix genome level for genetic diversity analysis are limited. In…
View article: 2,4-dinitroyoluene (2,4-DNT) exposure induced liver developmental damage and perturbs lipid metabolism and oxygen transport gene expression in zebrafish (Danio rerio)
2,4-dinitroyoluene (2,4-DNT) exposure induced liver developmental damage and perturbs lipid metabolism and oxygen transport gene expression in zebrafish (Danio rerio) Open
2,4-dinitrotoluene (2, 4-DNT) is a common environmental pollutant. The toxic effect on mammalian of 2,4-DNT has been well studied, but its toxicity on aquatic organisms is little known. In this study, zebrafish (Danio rerio) were exposed t…
View article: Hypoxia Stress Induces Tissue Damage, Immune Defense, and Oxygen Transport Change in Gill of Silver Carp (Hypophthalmichthys molitrix): Evaluation on Hypoxia by Using Transcriptomics
Hypoxia Stress Induces Tissue Damage, Immune Defense, and Oxygen Transport Change in Gill of Silver Carp (Hypophthalmichthys molitrix): Evaluation on Hypoxia by Using Transcriptomics Open
The silver carp ( Hypophthalmichthys molitrix ) is an economically, as well as environmentally, important fish that harbors low environmental hypoxia tolerance and frequently contributes to a loss of aquaculture productivity. The gill is t…
View article: Tandem Mass Tagging-Based Quantitative Proteomics Analysis Reveals Damage to the Liver and Brain of Hypophthalmichthys molitrix Exposed to Acute Hypoxia and Reoxygenation
Tandem Mass Tagging-Based Quantitative Proteomics Analysis Reveals Damage to the Liver and Brain of Hypophthalmichthys molitrix Exposed to Acute Hypoxia and Reoxygenation Open
Aquaculture environments frequently experience hypoxia and subsequent reoxygenation conditions, which have significant effects on hypoxia-sensitive fish populations. In this study, hepatic biochemical activity indices in serum and the cont…
View article: Molecular Characterization and Response of Prolyl Hydroxylase Domain (PHD) Genes to Hypoxia Stress in Hypophthalmichthys molitrix
Molecular Characterization and Response of Prolyl Hydroxylase Domain (PHD) Genes to Hypoxia Stress in Hypophthalmichthys molitrix Open
As an economically and ecologically important freshwater fish, silver carp (Hypophthalmichthys molitrix) is sensitive to low oxygen tension. Prolyl hydroxylase domain (PHD) proteins are critical regulators of adaptive responses to hypoxia …
View article: MicroRNAs May Play an Important Role in Sexual Reversal Process of Chinese Soft-Shelled Turtle, Pelodiscus sinensis
MicroRNAs May Play an Important Role in Sexual Reversal Process of Chinese Soft-Shelled Turtle, Pelodiscus sinensis Open
The Chinese soft-shelled (Pelodiscus sinensis) turtle exhibits obvious sex dimorphism, which leads to the higher economic and nutritional value of male individuals. Exogenous hormones can cause the transformation from male to female phenot…
View article: Identification of microRNAs in Silver Carp (Hypophthalmichthys molitrix) Response to Hypoxia Stress
Identification of microRNAs in Silver Carp (Hypophthalmichthys molitrix) Response to Hypoxia Stress Open
Hypoxia is one of the serious stresses in fish culture, which can lead to physical and morphological changes, and cause injury and even death to fish. Silver carp (Hypophthalmichthys molitrix) is an important economic fish and widely distr…
View article: Depletion of Survivin suppresses docetaxel-induced apoptosis in HeLa cells by facilitating mitotic slippage
Depletion of Survivin suppresses docetaxel-induced apoptosis in HeLa cells by facilitating mitotic slippage Open
View article: Suppression of Docetaxel induced apoptosis in Survivin-depleted cells due to failure of sustained mitotic block
Suppression of Docetaxel induced apoptosis in Survivin-depleted cells due to failure of sustained mitotic block Open
The antitumor effect of taxanes have been attributed to their ability to induce mitotic arrest through activation of the spindle assembly checkpoint. Cell death following prolonged mitotic arrest is mediated by the intrinsic apoptosis path…
View article: 2,4-Dinitrotoluene (DNT) Perturbs Yolk Absorption, Liver Development and Lipid Metabolism/Oxygen Transport Gene Expression in Zebrafish Embryos and Larvae
2,4-Dinitrotoluene (DNT) Perturbs Yolk Absorption, Liver Development and Lipid Metabolism/Oxygen Transport Gene Expression in Zebrafish Embryos and Larvae Open
2,4-dinitrotoluene (2,4-DNT) is a common environmental pollutant, and was classified as a group 2B human carcinogenic compound by the International Agency for Research on Cancer. This study determined the toxic effects of 2,4-DNT exposure …
View article: Development and Validation of Sex-Specific Markers in Pelodiscus Sinensis Using Restriction Site-Associated DNA Sequencing
Development and Validation of Sex-Specific Markers in Pelodiscus Sinensis Using Restriction Site-Associated DNA Sequencing Open
The sex of an animal influences its economic traits, especially in species displaying sexual dimorphism. The Chinese soft-shelled turtle, Pelodiscus sinensis, is an economically important aquatic species that shows significant male sexual …
View article: Inhibitor of the spindle assembly checkpoint surpasses apoptosis sensitizer in synergy with taxanes
Inhibitor of the spindle assembly checkpoint surpasses apoptosis sensitizer in synergy with taxanes Open
The antitumor effect of taxanes have been attributed to their ability to induce mitotic arrest through activation of the spindle assembly checkpoint. Cell death following prolonged mitotic arrest is mediated by the intrinsic apoptosis path…
View article: Correlation between the genetic polymorphism of ORMDL3 gene and asthma risk: a meta-analysis
Correlation between the genetic polymorphism of ORMDL3 gene and asthma risk: a meta-analysis Open
While increasing scientific evidence suggests that the ORMDL3 rs7216389 polymorphism may contribute to a higher susceptibility to asthma, many of the current studies have yielded inconclusive results. This meta-analysis aimed to assess the…