Hongbo Zhang
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View article: Assessing patient satisfaction in healthcare: Integrating ratings of service attributes and BERT-based analysis of comments
Assessing patient satisfaction in healthcare: Integrating ratings of service attributes and BERT-based analysis of comments Open
Patient satisfaction is critical to a health organization’s sustainability, making patient feedback an important source of insight for improving healthcare delivery. This study analyzes 31,054 patient responses across seven healthcare unit…
View article: [The application of porous polyethylene biological scaffolds combined with temporoparietal fascial flaps in auricular reconstruction].
[The application of porous polyethylene biological scaffolds combined with temporoparietal fascial flaps in auricular reconstruction]. Open
Objective:To analyze the application efficacy of employing high-density porous polyethylene （Su-por） in combination with temporoparietal fascial flaps via a minimally invasive scalp incision in auricular reconstruction. Methods:<…
View article: Dual physiological responsive structural color hydrogel particles for wound repair
Dual physiological responsive structural color hydrogel particles for wound repair Open
Hydrogel-based patches have demonstrated their values in diabetic wounds repair, particularly those intelligent dressings with continuous repair promoting and monitoring capabilities. Here, we propose a type of dual physiological responsiv…
View article: A Novel Device for Micro-Droplets Generation Based on the Stepwise Membrane Emulsification Principle
A Novel Device for Micro-Droplets Generation Based on the Stepwise Membrane Emulsification Principle Open
This paper presents a novel design of the device to generate microspheres or micro-droplets based on the membrane emulsification principle. Specifically, the novelty of the device lies in a proposed two-layer or stepwise (by generalization…
View article: Three-Dimensional Bioprinted Skin Microrelief and Its Role in Skin Aging
Three-Dimensional Bioprinted Skin Microrelief and Its Role in Skin Aging Open
Skin aging is a complex physiological process, in which cells and the extracellular matrix (ECM) interreact, which leads to a change in the mechanical properties of skin, which in turn affects the cell secretion and ECM deposition. The nat…
View article: Cell Migration Assays and Their Application to Wound Healing Assays—A Critical Review
Cell Migration Assays and Their Application to Wound Healing Assays—A Critical Review Open
In recent years, cell migration assays (CMAs) have emerged as a tool to study the migration of cells along with their physiological responses under various stimuli, including both mechanical and bio-chemical properties. CMAs are a generic …
View article: Miniaturized design of multi-octave PA using spoof surface plasmon polaritons
Miniaturized design of multi-octave PA using spoof surface plasmon polaritons Open
Surface Plasmon Polariton (SSPP), which exhibits subwavelength-scaled field confinement, can be realized at microwave frequencies by ultrathin corrugated metallic strips, providing significant potential for circuit and system miniaturizati…
View article: Self-supervised Event-based Monocular Depth Estimation using Cross-modal Consistency
Self-supervised Event-based Monocular Depth Estimation using Cross-modal Consistency Open
An event camera is a novel vision sensor that can capture per-pixel brightness changes and output a stream of asynchronous ``events''. It has advantages over conventional cameras in those scenes with high-speed motions and challenging ligh…
View article: A Novel Mechanomyography (MMG) Sensor Based on Piezo-Resistance Principle and with a Pyramidic Microarray
A Novel Mechanomyography (MMG) Sensor Based on Piezo-Resistance Principle and with a Pyramidic Microarray Open
Flexible piezoresistive sensors built by printing nanoparticles onto soft substrates are crucial for continuous health monitoring and wearable devices. In this study, a mechanomyography (MMG) sensor was developed using a flexible piezoresi…
View article: Rapid Evaluation of Anti-inflammatory Effect of Geniopicroside
Rapid Evaluation of Anti-inflammatory Effect of Geniopicroside Open
Skin acts as a barrier and is an important part of body immune system. External physical, biochemical and other stimuli might cause skin inflammation. Drugs and cosmetics have been developed for skin inflammation treatment. At present, the…
View article: The Additive Manufacturing Approach to Polydimethylsiloxane (PDMS) Microfluidic Devices: Review and Future Directions
The Additive Manufacturing Approach to Polydimethylsiloxane (PDMS) Microfluidic Devices: Review and Future Directions Open
This paper presents a comprehensive review of the literature for fabricating PDMS microfluidic devices by employing additive manufacturing (AM) processes. AM processes for PDMS microfluidic devices are first classified into (i) the direct …
View article: Inflammation Responses to Bone Scaffolds under Mechanical Stimuli in Bone Regeneration
Inflammation Responses to Bone Scaffolds under Mechanical Stimuli in Bone Regeneration Open
Physical stimuli play an important role in one tissue engineering. Mechanical stimuli, such as ultrasound with cyclic loading, are widely used to promote bone osteogenesis; however, the inflammatory response under physical stimuli has not …
View article: A High-Linearity Glucose Sensor Based on Silver-Doped Con A Hydrogel and Laser Direct Writing
A High-Linearity Glucose Sensor Based on Silver-Doped Con A Hydrogel and Laser Direct Writing Open
A continuous glucose monitoring (CGM) system is an ideal monitoring system for the blood glucose control of diabetic patients. The development of flexible glucose sensors with good glucose-responsive ability and high linearity within a lar…
View article: High-Linearity Hydrogel-Based Capacitive Sensor Based on Con A–Sugar Affinity and Low-Melting-Point Metal
High-Linearity Hydrogel-Based Capacitive Sensor Based on Con A–Sugar Affinity and Low-Melting-Point Metal Open
Continuous glucose monitoring (CGM) plays an important role in the treatment of diabetes. Affinity sensing based on the principle of reversible binding to glucose does not produce intermediates, and the specificity of concanavalin A (Con A…
View article: Switch-on mode of bioenergetic channels regulated by curcumin-loaded 3D composite scaffold to steer bone regeneration
Switch-on mode of bioenergetic channels regulated by curcumin-loaded 3D composite scaffold to steer bone regeneration Open
Metabolic energy to steer osteoblastic differentiation of bone marrow mesenchymal stem cells (BMSCs) could be a promising therapeutic target for bone tissue engineering (BTE), but prior knowledge of this issue is limited. To address bone d…
View article: The application of finite element analysis to determine the optimal UIV of growing-rod treatment in early-onset scoliosis
The application of finite element analysis to determine the optimal UIV of growing-rod treatment in early-onset scoliosis Open
Objectives: To analyze the stress distribution in the proximal vertebral body and soft tissue of dual growing-rod (GR) with different upper instrumented vertebra (UIV) to determine the optimal UIV. Methods: A ten-year-old male EOS case tre…
View article: A More Biomimetic Cell Migration Assay with High Reliability and Its Applications
A More Biomimetic Cell Migration Assay with High Reliability and Its Applications Open
Cell migration refers to the directional movement of cells to the surrounding cell-free zone in response to chemical and mechanical stimuli. A cell migration assay is an essential device for studying pharmaceutical and medical problems. In…
View article: Simulation of the Landing Buffer of a Three-Legged Jumping Robot
Simulation of the Landing Buffer of a Three-Legged Jumping Robot Open
In recent years, the research of planetary exploration robots has become an active field. The jumping robot has become a hot spot in this field. This paper presents a work modelling and simulating a three-legged jumping robot, which has a …
View article: Trypsin-Assisted Cell Depletion Method for Wound Healing Assay
Trypsin-Assisted Cell Depletion Method for Wound Healing Assay Open
View article: Research on Dynamic Range Analysis and Improvement of Imaging Equipment
Research on Dynamic Range Analysis and Improvement of Imaging Equipment Open
This paper proposes a dynamic range model and algorithm that analyzes several key factors that affect the dynamic range of imaging equipment. Through this model and algorithm, we analyze several modules that affect the dynamic range of the…
View article: Dielectrophoresis assisted high-throughput detection system for multiplexed immunoassays
Dielectrophoresis assisted high-throughput detection system for multiplexed immunoassays Open
Digital ELISA is introduced as a novel platform with unique advantages for detecting multiple kinds of single-molecule in the sample. How to improve the sensitivity of detection is the direction of current related research. Here, we report…
View article: Three-Dimensional Printing of Calcium Carbonate/Hydroxyapatite Scaffolds at Low Temperature for Bone Tissue Engineering
Three-Dimensional Printing of Calcium Carbonate/Hydroxyapatite Scaffolds at Low Temperature for Bone Tissue Engineering Open
Three-dimensional (3D) printing technology has been applied to fabricate bone tissue engineering scaffolds for a wide range of materials with precisely control over scaffold structures. Coral is a potential bone repair and bone replacement…
View article: Drug-attached magnetic nanoparticles: Locomotion control and in vivo biocompatibility
Drug-attached magnetic nanoparticles: Locomotion control and in vivo biocompatibility Open
Magnetic nanoparticles (MNPs) are playing an increasingly important role in the biomedical fields such as the diagnosis, treatment and monitoring of various diseases. Due to the unique properties of MNPs, MNPs with functionalized non-toxic…
View article: Efficient Drug Screening and Nephrotoxicity Assessment on Co-culture Microfluidic Kidney Chip
Efficient Drug Screening and Nephrotoxicity Assessment on Co-culture Microfluidic Kidney Chip Open
The function and susceptibility of various drugs are tested with renal proximal tubular epithelial cells; yet, replicating the morphology and kidneys function using the currently available in vitro models remains difficult. To overcome thi…
View article: 3D Bioprinting of the Sustained Drug Release Wound Dressing with Double-Crosslinked Hyaluronic-Acid-Based Hydrogels
3D Bioprinting of the Sustained Drug Release Wound Dressing with Double-Crosslinked Hyaluronic-Acid-Based Hydrogels Open
Hyaluronic acid (HA)-based hydrogels are widely used in biomedical applications due to their excellent biocompatibility. HA can be Ultraviolet (UV)-crosslinked by modification with methacrylic anhydride (HA-MA) and crosslinked by modificat…
View article: A Three-Layer Microfluidic Kidney Chip for Drug Nephrotoxicity Test
A Three-Layer Microfluidic Kidney Chip for Drug Nephrotoxicity Test Open
View article: Comparison of the degradation behavior of PLGA scaffolds in micro-channel, shaking, and static conditions
Comparison of the degradation behavior of PLGA scaffolds in micro-channel, shaking, and static conditions Open
Degradation of scaffolds is an important problem in tissue regeneration management. This paper reports a comparative study on degradation of the printed 3D poly (lactic-co-glycolic acid) scaffold under three conditions, namely, micro-chann…
View article: Three-dimensional bioprinting is not only about cell-laden structures
Three-dimensional bioprinting is not only about cell-laden structures Open
View article: Modeling And Validation Of Microspheres Generation In The Modified T-Junction Device
Modeling And Validation Of Microspheres Generation In The Modified T-Junction Device Open
This paper presents a model for a modified T-junction device for microspheres generation. The numerical model is developed using a commercial software package: COMSOL Multiphysics. In order to test the accuracy of the numerical model, mult…