Huangan Wu
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View article: Acupuncturist Roles in the Perioperative Period: How Far Are We From Clinical Integration?
Acupuncturist Roles in the Perioperative Period: How Far Are We From Clinical Integration? Open
View article: Effectiveness and safety of acupuncture for Parkinson’s disease anxiety: a systematic review and meta-analysis
Effectiveness and safety of acupuncture for Parkinson’s disease anxiety: a systematic review and meta-analysis Open
Background Individuals with Parkinson’s disease (PD) commonly experience anxiety, with a prevalence of 31%. This study systematically evaluates the efficacy and safety of acupuncture for anxiety related to PD. Method Nine databases were se…
View article: Moxibustion modulates gut microbiota and improves bone marrow hematopoiesis in mice with myelosuppression-induced aplastic anemia
Moxibustion modulates gut microbiota and improves bone marrow hematopoiesis in mice with myelosuppression-induced aplastic anemia Open
Objective: To observe the effects of moxibustion on the hematopoietic function in mice with aplastic anemia (AA) induced by bone marrow (BM) suppression, and to investigate the intervention effects of moxibustion on AA from the perspective…
View article: Efficacy of electroacupuncture on insomnia disorder in older adults: study protocol for a multicentre randomised controlled trial
Efficacy of electroacupuncture on insomnia disorder in older adults: study protocol for a multicentre randomised controlled trial Open
Introduction Insomnia disorder is highly prevalent among older adults and is associated with significant adverse effects on both physical and psychological health. The use of hypnotic medications in this population is often accompanied by …
View article: The Impact of Social Media on Chinese University Graduates' Perception of the Entrepreneurial Ecosystem and Their Intention to Return Hometown for Entrepreneurship
The Impact of Social Media on Chinese University Graduates' Perception of the Entrepreneurial Ecosystem and Their Intention to Return Hometown for Entrepreneurship Open
In the era of pervasive social media, college graduates’ intention to return to their hometowns for entrepreneurship is shaped by the complex interplay of multiple forces. This study adopts a mixed-method approach combining fuzzy-set Quali…
View article: Machine learning in the differential diagnosis of ulcerative colitis and Crohn’s disease: a systematic review
Machine learning in the differential diagnosis of ulcerative colitis and Crohn’s disease: a systematic review Open
Our findings indicate that ML holds the potential to enhance diagnostic accuracy in distinguishing between ulcerative colitis and CD, particularly through the utilization of models developed from endoscopic and fecal biomarker data based o…
View article: Optimization and principles of acupoint selection and coordination in the treatment of adult abdominal obesity using acupuncture and moxibustion over the past decade: A data mining
Optimization and principles of acupoint selection and coordination in the treatment of adult abdominal obesity using acupuncture and moxibustion over the past decade: A data mining Open
Objective: To explore the optimization and principles of acupoint selection and coordination in the treatment of adult abdominal obesity using acupuncture and moxibustion over the past decade using data mining. Methods: Clinical studies of…
View article: Cardio-cerebral protective effect of moxibustion on phlegm-dampness type hypertension: a study protocol of a randomized clinical trial (Preprint)
Cardio-cerebral protective effect of moxibustion on phlegm-dampness type hypertension: a study protocol of a randomized clinical trial (Preprint) Open
View article: Eliciting Dual-Niche Immunological Priming by Acupoint Delivery of Nanovaccines
Eliciting Dual-Niche Immunological Priming by Acupoint Delivery of Nanovaccines Open
View article: Grain-sized moxibustion activates dendritic cells to enhance the antitumor immunity of cancer vaccines
Grain-sized moxibustion activates dendritic cells to enhance the antitumor immunity of cancer vaccines Open
View article: Curcumenol inhibits malignant progression and promotes ferroptosis via the SLC7A11/NF‑κB/TGF‑β pathway in triple‑negative breast cancer
Curcumenol inhibits malignant progression and promotes ferroptosis via the SLC7A11/NF‑κB/TGF‑β pathway in triple‑negative breast cancer Open
Triple‑negative breast cancer (TNBC) exhibits a high degree of malignancy and a propensity for metastasis, ultimately resulting in unfavorable patient outcomes. Curcuma phaeocaulis Valeton is a common herb used in traditional Chines…
View article: Effect of moxibustion on P2X7R/NF-κB pathway in ulcerative colitis rats with repeated induction of DSS
Effect of moxibustion on P2X7R/NF-κB pathway in ulcerative colitis rats with repeated induction of DSS Open
Objective: To investigate the mechanism by which moxibustion regulates the expression of inflammatory cytokines in ulcerative colitis (UC) rats through the P2X7 receptor (P2X7R)/nuclear factor-kappa B (NF-κB) pathway. Methods: UC was induc…
View article: Moxibustion regulates KDM4D expression and modulates lipid metabolism to inhibit tumor proliferation in CAC mice
Moxibustion regulates KDM4D expression and modulates lipid metabolism to inhibit tumor proliferation in CAC mice Open
View article: The Role of Herb-Partitioned Moxibustion in the Angiogenesis of Colitis-Associated Cancer in Rats
The Role of Herb-Partitioned Moxibustion in the Angiogenesis of Colitis-Associated Cancer in Rats Open
HPM plays a role in inhibiting CAC angiogenesis. This study may provide new evidence at the macroscopic level of vascular architecture for HPM to inhibit the progression of CAC by FDISCO tissue clearing technique for 3D imaging.
View article: Unraveling the breast cancer tumor microenvironment: crucial factors influencing natural killer cell function and therapeutic strategies
Unraveling the breast cancer tumor microenvironment: crucial factors influencing natural killer cell function and therapeutic strategies Open
Natural killer (NK) cells have emerged as a novel and effective treatment for breast cancer. Nevertheless, the breast cancer tumor microenvironment (TME) manifests multiple immunosuppressive mechanisms, impeding the proper execution of NK …
View article: Modulation of colonic DNA methyltransferase by mild moxibustion and electroacupuncture in ulcerative colitis TET2 knockout mice
Modulation of colonic DNA methyltransferase by mild moxibustion and electroacupuncture in ulcerative colitis TET2 knockout mice Open
Objective: To investigate the mechanism of in alleviating colonic mucosal inflammation in ten-eleven translocation (TET) protein 2 gene knockout (TET2-/-) mice with ulcerative colitis (UC) by regulating DNA methyltransferase (DNMT) and DNA…
View article: P2X7 and P2Y1 receptors in DRG mediate electroacupuncture to inhibit peripheral sensitization in rats with IBS visceral pain
P2X7 and P2Y1 receptors in DRG mediate electroacupuncture to inhibit peripheral sensitization in rats with IBS visceral pain Open
View article: A bibliometric analysis and visualization of acupuncture and moxibustion therapy for herpes zoster and postherpetic neuralgia
A bibliometric analysis and visualization of acupuncture and moxibustion therapy for herpes zoster and postherpetic neuralgia Open
Objective To identify major contributors, current research status, and to forecast research trends and future development prospects on acupuncture and moxibustion therapy for herpes zoster (HZ) and postherpetic neuralgia (PHN). Methods A s…
View article: Observation of the immediate effect of ultrasound-guided acupuncture at Zusanli (ST36) point on Blood flow volume in lower limb arteries: a randomized controlled trial study protocol
Observation of the immediate effect of ultrasound-guided acupuncture at Zusanli (ST36) point on Blood flow volume in lower limb arteries: a randomized controlled trial study protocol Open
Background The Zusanli(ST36) point, as one of the key health care points, has a wide range of indications and various effects. Given its effectiveness in regulating qi and blood flow, we investigated its direct impact on the arteries of th…
View article: Research progress on acupuncture and moxibustion for treatment of Crohn's disease based on the regulation of innate immunity
Research progress on acupuncture and moxibustion for treatment of Crohn's disease based on the regulation of innate immunity Open
Crohn's disease (CD) is an inflammatory bowel disease whose pathogenesis remains unclear. In this paper, we reviewed the basic research of acupuncture and moxibustion in treating CD by regulating intestinal intrinsic immunity, and summariz…
View article: Acupuncture for endometriosis-associated infertility: Study protocol for a randomized controlled trial
Acupuncture for endometriosis-associated infertility: Study protocol for a randomized controlled trial Open
Background: Acupuncture has been proven to improve the pregnancy rate in infertile women. Endometriosis is a common cause of infertility. So far, there are no studies of the efficacy of acupuncture on endometriosis-associated infertility (…
View article: Clinical study of electroacupuncture on the recovery of gastrointestinal dysfunction after laparoscopic surgery for gastrointestinal cancer - study protocol for a randomized controlled trial
Clinical study of electroacupuncture on the recovery of gastrointestinal dysfunction after laparoscopic surgery for gastrointestinal cancer - study protocol for a randomized controlled trial Open
View article: Moxibustion alleviates intestinal inflammation in ulcerative colitis rats by modulating long non-coding RNA LOC108352929 and inhibiting Phf11 expression
Moxibustion alleviates intestinal inflammation in ulcerative colitis rats by modulating long non-coding RNA LOC108352929 and inhibiting Phf11 expression Open
Long noncoding RNA (lncRNAs) are involved in the pathogenesis of ulcerative colitis (UC). Moxibustion, a traditional Chinese medicine, can improve symptoms in patients with UC and reduce intestinal inflammation in rats with UC. However, it…
View article: An orally available small molecule BCL6 inhibitor effectively suppresses diffuse large B cell lymphoma cells growth in vitro and in vivo
An orally available small molecule BCL6 inhibitor effectively suppresses diffuse large B cell lymphoma cells growth in vitro and in vivo Open
Background and Purpose: The transcription factor B cell lymphoma 6 (BCL6) is an oncogenic driver of diffuse large B cell lymphoma (DLBCL). Blocking the protein-protein interactions of BCL6 and its corepressors has been proposed as an effec…
View article: Research progress and key scientific problems of traditional Chinese moxibustion
Research progress and key scientific problems of traditional Chinese moxibustion Open
View article: RETRACTED: Grain-sized moxibustion enhances anti-tumor immunity of tumor cell lysate vaccine by inhibiting β-adrenergic signal pathway
RETRACTED: Grain-sized moxibustion enhances anti-tumor immunity of tumor cell lysate vaccine by inhibiting β-adrenergic signal pathway Open
The authors have requested that this preprint be removed from Research Square.
View article: Acupuncture and moxibustion therapy for cognitive impairment: the microbiome–gut–brain axis and its role
Acupuncture and moxibustion therapy for cognitive impairment: the microbiome–gut–brain axis and its role Open
Cognitive impairment poses a significant burden on individuals, families, and society worldwide. Despite the lack of effective treatment strategies, emerging evidence suggests that the microbiome–gut–brain (MGB) axis may play a critical ro…
View article: Efficacy and Safety of Different Acupuncture Therapies for Patients with Ulcerative Colitis:A Systematic Review And Network Meta-Analysis
Efficacy and Safety of Different Acupuncture Therapies for Patients with Ulcerative Colitis:A Systematic Review And Network Meta-Analysis Open
View article: Deciphering the Proteome: Novel Therapeutic Targets and Side Effect Profiling for Ulcerative Colitis Using Mendelian Randomization and Phewas Analyses
Deciphering the Proteome: Novel Therapeutic Targets and Side Effect Profiling for Ulcerative Colitis Using Mendelian Randomization and Phewas Analyses Open
View article: Moxibustion Regulates the BRG1/Nrf2/HO‐1 Pathway by Inhibiting MicroRNA‐222‐3p to Prevent Oxidative Stress in Intestinal Epithelial Cells in Ulcerative Colitis and Colitis‐Associated Colorectal Cancer
Moxibustion Regulates the BRG1/Nrf2/HO‐1 Pathway by Inhibiting MicroRNA‐222‐3p to Prevent Oxidative Stress in Intestinal Epithelial Cells in Ulcerative Colitis and Colitis‐Associated Colorectal Cancer Open
Oxidative stress is crucial in ulcerative colitis (UC) and colitis‐associated colorectal cancer (CAC). Intestinal epithelial cells (IECs) are an important component of the intestinal barrier. In previous studies, we have demonstrated that …