Hankui Chen
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View article: Quantification of tRNA m<sup>1</sup>A modification by templated-ligation qPCR
Quantification of tRNA m<sup>1</sup>A modification by templated-ligation qPCR Open
N1-methyladenosine (m 1 A) is a widespread modification in all eukaryotic, many archaeal, and some bacterial tRNAs. M 1 A is generally located in the T loop of cytosolic tRNA and between acceptor and D stems of mitochondrial tRNAs, it is i…
View article: Plasma small ncRNA pair panels as novel biomarkers for early-stage lung adenocarcinoma screening
Plasma small ncRNA pair panels as novel biomarkers for early-stage lung adenocarcinoma screening Open
Several small ncRNA pair ratios were identified as markers capable of discerning patients with LAC from those with benign lesions or high-risk control individuals.
View article: Global lipidomics reveals two plasma lipids as novel biomarkers for the detection of squamous cell lung cancer: A pilot study
Global lipidomics reveals two plasma lipids as novel biomarkers for the detection of squamous cell lung cancer: A pilot study Open
Lipids are known to serve important roles in energy storage, membrane structure and signal transduction as well as in human cancers. In the present study, lipidomics was employed in order to identify plasma lipid markers for the early dete…
View article: Global lipidomics identified plasma lipids as novel biomarkers for early detection of lung cancer
Global lipidomics identified plasma lipids as novel biomarkers for early detection of lung cancer Open
Using lipidomics we identified several lipid markers capable of discerning early stage lung carcinoma from healthy individuals, which might be further developed as a quick, safe blood test for early diagnosis of this disease.
View article: Plasma lipidomics profiling identified lipid biomarkers in distinguishing early-stage breast cancer from benign lesions
Plasma lipidomics profiling identified lipid biomarkers in distinguishing early-stage breast cancer from benign lesions Open
The combination of these 15 lipid species as a panel could be used as plasma biomarkers for the diagnosis of breast cancer.
View article: Evaluation of Plasma miR-21 and miR-152 as Diagnostic Biomarkers for Common Types of Human Cancers
Evaluation of Plasma miR-21 and miR-152 as Diagnostic Biomarkers for Common Types of Human Cancers Open
Stable blood based miRNA species have allowed for the differentiation of patients with various types of cancer. Therefore, specific blood-based miRNA might be considered as a methodology which could be informative of the presence of cancer…