John Hannah
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View article: The structure of efrotomycin.
The structure of efrotomycin. Open
The antibiotic efrotomycin (I), C59H88N2O20, was isolated from cultures of Nocardia lactamdurans as an amorphous yellow powder. Mass spectral and NMR analyses show that the compound is a glycoside of the known antibiotic aurodox (II), C44H…
View article: Discovery of diflunisal.
Discovery of diflunisal. Open
1 Diflunisal (MK-647; 5-(2,4-difluorophenyl)-salicylic acid) is a new analgesic anti-inflammatory agent discovered after an extensive chemical and pharmacological study from 1962-71. 2 In the search for a superior salicylate our objectives…