Hannah Donkers
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View article: Abnormal preoperative haematological parameters in Endometrial cancer; reflecting tumour aggressiveness or reduced response to radiotherapy?
Abnormal preoperative haematological parameters in Endometrial cancer; reflecting tumour aggressiveness or reduced response to radiotherapy? Open
Current data demonstrate the importance of preoperative anaemia as independent prognostic factor in patients with EC. Moreover, anaemia seems to be associated with reduced response to radiotherapy. Prospective validation in a larger study …
View article: Abnormal preoperative haematological parameters in Endometrial cancer; reflecting tumour aggressiveness or reduced response to radiotherapy?
Abnormal preoperative haematological parameters in Endometrial cancer; reflecting tumour aggressiveness or reduced response to radiotherapy? Open
In endometrial cancer (EC), preoperative anaemia, thrombocytosis and leucocytosis appear to be associated with worse prognosis. It remains unclear whether these parameters solely reflect tumour aggressiveness, or also impact response to ad…
View article: Usefulness of microRNA detection in the diagnostics of endometrial cancer
Usefulness of microRNA detection in the diagnostics of endometrial cancer Open
Introduction MicroRNAs (miRNAs) are noncoding RNAs that regulate gene expression and contribute to the development of cancer. They have been shown to be stable in tissue samples and may be promising diagnostic biomarkers for endometrial ca…
View article: 426 The diagnostic value of microRNA signature in endometrial cancer
426 The diagnostic value of microRNA signature in endometrial cancer Open
Background MiRNAs are noncoding RNAs that regulate gene expression and contribute to the development of cancer. MiRNAs have been shown to be stable in urine, serum and tissue samples. They may be promising biomarkers for non-invasive detec…
View article: 174 Obesity and visceral fat: survival impact in endometrial cancer
174 Obesity and visceral fat: survival impact in endometrial cancer Open
Background Obesity is an important risk factor for the development of endometrial cancer and is associated with poor outcomes. However, the impact of body fat distribution on survival and surgical outcomes in endometrial cancer patients is…
View article: Real World Patterns of PSA Response and Survival with Abiraterone and Enzalutamide in Metastatic Castrate Resistant Prostate Cancer (mCRPC)
Real World Patterns of PSA Response and Survival with Abiraterone and Enzalutamide in Metastatic Castrate Resistant Prostate Cancer (mCRPC) Open
Background: We investigated our institution’s mCRPC enzalutamide or abiraterone patients examining PSA responses and impact of sequencing of these drugs. Methods: All enzalutamide / abiraterone mCRPC patients (2011-2018) were included. Rat…
View article: Diagnostic value of microRNA panel in endometrial cancer: A systematic review
Diagnostic value of microRNA panel in endometrial cancer: A systematic review Open
miRNAs yield a promising diagnostic biomarker potential in endometrial cancer, especially miR-205, the miR-200 family and miR-135b, -182, -183 and -223. However, no sufficient high quality data are available to draw hard conclusions. More …
View article: Laparoscopy versus laparotomy for the management of early stage endometrial cancer
Laparoscopy versus laparotomy for the management of early stage endometrial cancer Open
Background This is an update of a previous Cochrane Review published in 2012, Issue 9. Surgery for endometrial cancer (hysterectomy with removal of both fallopian tubes and ovaries) is performed through laparotomy. It has been suggested th…