Hannah Mandle
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View article: Inflammation and gut barrier function-related genes and colorectal cancer risk in western European populations
Inflammation and gut barrier function-related genes and colorectal cancer risk in western European populations Open
Gut barrier dysfunction and related inflammation are known to be associated with the development and progression of colorectal cancer (CRC). We investigated associations of 292 single-nucleotide polymorphisms (SNPs) from 27 genes related t…
View article: The Association between Mediated Deprivation and Ovarian Cancer Survival among African American Women
The Association between Mediated Deprivation and Ovarian Cancer Survival among African American Women Open
Background: Deprivation indices are often used to adjust for socio-economic disparities in health studies. Their role has been partially evaluated for certain population-level cancer outcomes, but examination of their role in ovarian cance…
View article: Data from Effects of Supplemental Calcium and Vitamin D on Expression of Toll-Like Receptors and Phospho-IKKα/β in the Normal Rectal Mucosa of Colorectal Adenoma Patients
Data from Effects of Supplemental Calcium and Vitamin D on Expression of Toll-Like Receptors and Phospho-IKKα/β in the Normal Rectal Mucosa of Colorectal Adenoma Patients Open
Chronic inflammation in the colorectum, a significant contributor to colorectal carcinogenesis, can be triggered by the activation of proinflammatory signaling pathways such as those initiated by Toll-like receptors (TLR) and nuclear facto…
View article: Supplementary Tables S1-S5 from Effects of Supplemental Calcium and Vitamin D on Expression of Toll-Like Receptors and Phospho-IKKα/β in the Normal Rectal Mucosa of Colorectal Adenoma Patients
Supplementary Tables S1-S5 from Effects of Supplemental Calcium and Vitamin D on Expression of Toll-Like Receptors and Phospho-IKKα/β in the Normal Rectal Mucosa of Colorectal Adenoma Patients Open
Table S1. pIKKα/β, TLR4, and TLR5 Expression in the Full Length of Crypts and Stroma in the Differentiation Zone (Upper 40%) in the Normal-Appearing Rectal Mucosa of the Adjunct Biomarker Study Table S2. pIKKα/β, TLR4, and TLR5 Express…
View article: Data from Effects of Supplemental Calcium and Vitamin D on Expression of Toll-Like Receptors and Phospho-IKKα/β in the Normal Rectal Mucosa of Colorectal Adenoma Patients
Data from Effects of Supplemental Calcium and Vitamin D on Expression of Toll-Like Receptors and Phospho-IKKα/β in the Normal Rectal Mucosa of Colorectal Adenoma Patients Open
Chronic inflammation in the colorectum, a significant contributor to colorectal carcinogenesis, can be triggered by the activation of proinflammatory signaling pathways such as those initiated by Toll-like receptors (TLR) and nuclear facto…
View article: Supplementary Tables S1-S5 from Effects of Supplemental Calcium and Vitamin D on Expression of Toll-Like Receptors and Phospho-IKKα/β in the Normal Rectal Mucosa of Colorectal Adenoma Patients
Supplementary Tables S1-S5 from Effects of Supplemental Calcium and Vitamin D on Expression of Toll-Like Receptors and Phospho-IKKα/β in the Normal Rectal Mucosa of Colorectal Adenoma Patients Open
Table S1. pIKKα/β, TLR4, and TLR5 Expression in the Full Length of Crypts and Stroma in the Differentiation Zone (Upper 40%) in the Normal-Appearing Rectal Mucosa of the Adjunct Biomarker Study Table S2. pIKKα/β, TLR4, and TLR5 Express…
View article: Deprivation and Segregation in Ovarian cancer survival among African American Women: a mediated analysis
Deprivation and Segregation in Ovarian cancer survival among African American Women: a mediated analysis Open
Background Deprivation and segregation indices are often examined as possible explanations for observed health disparities in population-based studies. In this study we assessed the role of recognized deprivation and segregation indices sp…
View article: Survival of epithelial ovarian cancer in Black women: a society to cell approach in the African American Cancer Epidemiology Study (AACES)
Survival of epithelial ovarian cancer in Black women: a society to cell approach in the African American Cancer Epidemiology Study (AACES) Open
Purpose: The five-year relative survival for epithelial ovarian cancer (EOC) is worse among Black women compared with White women. The causes for this disparity are likely multi-factorial but unclear as to date, no cohort study has focused…
View article: Vitamin D-Related Genes, Blood Vitamin D Levels and Colorectal Cancer Risk in Western European Populations
Vitamin D-Related Genes, Blood Vitamin D Levels and Colorectal Cancer Risk in Western European Populations Open
Higher circulating 25-hydroxyvitamin D levels (25(OH)D) have been found to be associated with lower risk for colorectal cancer (CRC) in prospective studies. Whether this association is modified by genetic variation in genes related to vita…
View article: Effects of supplemental calcium and vitamin D on tight‐junction proteins and mucin‐12 expression in the normal rectal mucosa of colorectal adenoma patients
Effects of supplemental calcium and vitamin D on tight‐junction proteins and mucin‐12 expression in the normal rectal mucosa of colorectal adenoma patients Open
The physical gut barrier, comprised of a thick mucus layer and the epithelium, plays an important role in defense against microbes and foreign antigens. Calcium and vitamin D may be involved in maintaining the integrity of the intestinal m…
View article: Association of Unintended Pregnancy With Spontaneous Fetal Loss in Women With Epilepsy
Association of Unintended Pregnancy With Spontaneous Fetal Loss in Women With Epilepsy Open
The Epilepsy Birth Control Registry retrospective survey finding that unplanned pregnancy in women with epilepsy may double the risk for SFL warrants prospective investigation with outcome verification.
View article: Reasons for discontinuation of reversible contraceptive methods by women with epilepsy
Reasons for discontinuation of reversible contraceptive methods by women with epilepsy Open
Summary Objective To report the reasons for discontinuation of contraceptive methods by women with epilepsy ( WWE ). Methods These retrospective data come from a web‐based survey regarding the contraceptive practices of 1,144 WWE in the co…
View article: Differential impact of contraceptive methods on seizures varies by antiepileptic drug category: Findings of the Epilepsy Birth Control Registry
Differential impact of contraceptive methods on seizures varies by antiepileptic drug category: Findings of the Epilepsy Birth Control Registry Open
The findings provide community-based, epidemiological survey evidence that contraceptive methods may differ in their impact on seizures and that this impact may vary by antiepileptic drug category.
View article: Contraceptive practices of women with epilepsy: Findings of the epilepsy birth control registry
Contraceptive practices of women with epilepsy: Findings of the epilepsy birth control registry Open
Summary Objective To report the contraceptive practices of women with epilepsy ( WWE ) in the community, predictors of highly effective contraception use, and reasons WWE provide for the selection of a particular method. Methods These cros…