Hannah Mitländer
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View article: CCR3 deficiency shifts adaptive to innate-driven immunity in asthma
CCR3 deficiency shifts adaptive to innate-driven immunity in asthma Open
Taken together, this work demonstrates the functional involvement of CCR3 in both innate and adaptive immune cells in the lung during asthma pathogenesis.
View article: Poly I:C Pre-Treatment Induced the Anti-Viral Interferon Response in Airway Epithelial Cells
Poly I:C Pre-Treatment Induced the Anti-Viral Interferon Response in Airway Epithelial Cells Open
Type I and III interferons are among the most important antiviral mediators. Increased susceptibility to infections has been described as being associated with impaired interferon response in asthmatic patients. In this work, we focused on…
View article: Vitamin D3 resolved human and experimental asthma via B lymphocyte–induced maturation protein 1 in T cells and innate lymphoid cells
Vitamin D3 resolved human and experimental asthma via B lymphocyte–induced maturation protein 1 in T cells and innate lymphoid cells Open
Supplementing VitD3 resulted in amelioration of clinical asthma manifestations in human studies as well as in experimental allergic asthma, indicating that VitD3 shifts proinflammatory immune responses to anti-inflammatory immune responses…
View article: Rhinovirus Suppresses TGF-β-GARP Presentation by Peripheral NK Cells
Rhinovirus Suppresses TGF-β-GARP Presentation by Peripheral NK Cells Open
Asthma is a chronic airway disease whose exacerbations are often triggered by rhinovirus infection. TGF-β1 induces rhinovirus replication in infected cells. Moreover, TGF-β1 is a pleiotropic mediator that is produced by many immune cells i…
View article: Corrigendum: Mechanism of Rhinovirus Immunity and Asthma
Corrigendum: Mechanism of Rhinovirus Immunity and Asthma Open
[This corrects the article DOI: 10.3389/fimmu.2021.731846.].
View article: Mechanism of Rhinovirus Immunity and Asthma
Mechanism of Rhinovirus Immunity and Asthma Open
The majority of asthma exacerbations in children are caused by Rhinovirus (RV), a positive sense single stranded RNA virus of the Picornavirus family. The host has developed virus defense mechanisms that are mediated by the upregulation of…