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View article: Cost-effectiveness of a periodic fasting-mimicking diet programme in patients with type 2 diabetes: a trial-based analysis and a lifetime model-based analysis
Cost-effectiveness of a periodic fasting-mimicking diet programme in patients with type 2 diabetes: a trial-based analysis and a lifetime model-based analysis Open
Background The prevalence of type 2 diabetes continues to rise worldwide, which is associated with a decrease in quality of Life and an increase in healthcare costs. The aim of this study was to determine cost-effectiveness of a one year m…
View article: <i>Your Lifestyle As Medicine</i> : the impact of a citizen initiative for people with type 2 diabetes using peer coaching and self-management
<i>Your Lifestyle As Medicine</i> : the impact of a citizen initiative for people with type 2 diabetes using peer coaching and self-management Open
Background and aim Sustained lifestyle changes are crucial for the remission of type 2 diabetes (T2D) but remain challenging. Citizen initiatives using peer coaching and self-management may offer a promising alternative to professional med…
View article: Feasibility of following a fasting-mimicking diet programme in persons with type 2 diabetes – a mixed-methods study
Feasibility of following a fasting-mimicking diet programme in persons with type 2 diabetes – a mixed-methods study Open
Background & Aims A fasting-mimicking programme in primary care demonstrated metabolic benefits for persons with type 2 diabetes (T2D). This study evaluated the feasibility of this approach. Methods Persons with T2D who used metformin or n…
View article: Knowledge, attitude, and practice regarding type 2 diabetes and associated factors among rural adolescents in Indonesia: A cross-sectional study
Knowledge, attitude, and practice regarding type 2 diabetes and associated factors among rural adolescents in Indonesia: A cross-sectional study Open
Background Type 2 diabetes (T2D) is increasingly affecting adolescents globally, yet there is limited evidence on their knowledge, attitudes, and practices (KAP) regarding the disease, which is essential for promoting preventive strategies…
View article: Publisher Correction: Fasting mimicking diet cycles versus a Mediterranean diet and cardiometabolic risk in overweight and obese hypertensive subjects: a randomized clinical trial
Publisher Correction: Fasting mimicking diet cycles versus a Mediterranean diet and cardiometabolic risk in overweight and obese hypertensive subjects: a randomized clinical trial Open
View article: A fasting-mimicking diet programme reduces abdominal adipose tissue while preserving abdominal muscle mass in persons with type 2 diabetes
A fasting-mimicking diet programme reduces abdominal adipose tissue while preserving abdominal muscle mass in persons with type 2 diabetes Open
ClinicalTrials.gov: NCT03811587, 05-11-2018.
View article: A fasting-mimicking diet programme reduces liver fat and liver inflammation/fibrosis measured by magnetic resonance imaging in patients with type 2 diabetes
A fasting-mimicking diet programme reduces liver fat and liver inflammation/fibrosis measured by magnetic resonance imaging in patients with type 2 diabetes Open
ClinicalTrials.gov: NCT03811587.
View article: Differential effects of lifestyle interventions on continuous glucose monitoring metrics in persons with type 2 diabetes: a randomized cross-over trial
Differential effects of lifestyle interventions on continuous glucose monitoring metrics in persons with type 2 diabetes: a randomized cross-over trial Open
Background The effects of lifestyle on glucose metabolism significantly differ between individuals. Hyperglycemia in type 2 diabetes is driven by tissue-specific insulin resistance and reduced beta-cell capacity, whose relative contributio…
View article: Fasting-mimicking diet in type 2 diabetes reduces myocardial triglyceride content: A 12-month randomised controlled trial
Fasting-mimicking diet in type 2 diabetes reduces myocardial triglyceride content: A 12-month randomised controlled trial Open
ClinicalTrials.gov; NCT03811587, submitted January 13th, 2019.
View article: Simplifying coronary artery disease risk stratification: development and validation of a questionnaire-based alternative comparable to clinical risk tools
Simplifying coronary artery disease risk stratification: development and validation of a questionnaire-based alternative comparable to clinical risk tools Open
View article: Effect of Thyroid Status Modulation on Pituitary and Peripheral Hormone Concentrations in Healthy Older Subjects
Effect of Thyroid Status Modulation on Pituitary and Peripheral Hormone Concentrations in Healthy Older Subjects Open
Introduction: Depending on age, sex, and familial longevity, alterations in thyroid status occur frequently and often co-occur with differences in other hormonal axes. However, studies that explore the effects of thyroid status modulation …
View article: Differential impact of lifestyle factors on 2-hour glucose values in individuals with type 2 diabetes: potential for more personalized interventions
Differential impact of lifestyle factors on 2-hour glucose values in individuals with type 2 diabetes: potential for more personalized interventions Open
Introduction Lifestyle determinants of 2-hour glucose concentration in people with type 2 diabetes and interindividual differences need to be identified. Research design and methods 38 participants with type 2 diabetes, treated with lifest…
View article: Measuring energy expenditure in narcolepsy using doubly labeled water and respiration chamber calorimetry
Measuring energy expenditure in narcolepsy using doubly labeled water and respiration chamber calorimetry Open
Study Objectives Hypocretin deficiency causes type 1 narcolepsy, a condition characterized by excessive daytime sleepiness, cataplexy, and fragmented nocturnal sleep. Two-thirds of people with narcolepsy are also overweight, of which half …
View article: Food and Health Literacy in Patients Awaiting Metabolic-Bariatric Surgery
Food and Health Literacy in Patients Awaiting Metabolic-Bariatric Surgery Open
Introduction: Specialized lifestyle programmes for patients undergoing metabolic-bariatric surgery (MBS) are provided to facilitate adjustment and adherence to a healthy lifestyle after surgery. However, pre-programme food and health liter…
View article: International consensus on fasting terminology
International consensus on fasting terminology Open
Although fasting is increasingly applied for disease prevention and treatment, consensus on terminology is lacking. Using Delphi methodology, an international, multidisciplinary panel of researchers and clinicians standardized definitions …
View article: Challenges in Type 2 Diabetes Prevention among Senior High School Students: A Qualitative Study.
Challenges in Type 2 Diabetes Prevention among Senior High School Students: A Qualitative Study. Open
An evidence-based, well-organized, and systematic school-based diabetes prevention program is fundamental to help overcome challenges and prevent future T2DM incidence. It requires relevant stakeholders' high level of awareness, strong col…
View article: Self-initiated lifestyle changes during a fasting-mimicking diet programme in patients with type 2 diabetes: a mixed-methods study
Self-initiated lifestyle changes during a fasting-mimicking diet programme in patients with type 2 diabetes: a mixed-methods study Open
View article: Impact of dietary carbohydrate, fat or protein restriction on the human gut microbiome: a systematic review
Impact of dietary carbohydrate, fat or protein restriction on the human gut microbiome: a systematic review Open
Restriction of dietary carbohydrates, fat and/or protein is often used to reduce body weight and/or treat (metabolic) diseases. Since diet is a key modulator of the human gut microbiome, which plays an important role in health and disease,…
View article: Role of dietary interventions on microvascular health in South-Asian Surinamese people with type 2 diabetes in the Netherlands: A randomized controlled trial
Role of dietary interventions on microvascular health in South-Asian Surinamese people with type 2 diabetes in the Netherlands: A randomized controlled trial Open
View article: Integration of a fasting-mimicking diet programme in primary care for type 2 diabetes reduces the need for medication and improves glycaemic control: a 12-month randomised controlled trial
Integration of a fasting-mimicking diet programme in primary care for type 2 diabetes reduces the need for medication and improves glycaemic control: a 12-month randomised controlled trial Open
Aims/hypothesis The aim of this study was to evaluate the impact on metabolic control of periodic use of a 5-day fasting-mimicking diet (FMD) programme as an adjunct to usual care in people with type 2 diabetes under regular primary care s…
View article: The Effects of Various Dietary and Exercise Interventions on Continuously Measured Glucose Levels in People with Type 2 Diabetes, and Potential for Personalized Treatment
The Effects of Various Dietary and Exercise Interventions on Continuously Measured Glucose Levels in People with Type 2 Diabetes, and Potential for Personalized Treatment Open
Introduction: Dietary and physical activity interventions have beneficials health effects for people with type 2 diabetes (T2D). Although the effects of such interventions on long-term changes in glucose levels are well studied in a contro…
View article: Questionnaire-Based Prediction of Incident Coronary Artery Disease: Developing and Validating Machine Learning Models for Multiple Populations
Questionnaire-Based Prediction of Incident Coronary Artery Disease: Developing and Validating Machine Learning Models for Multiple Populations Open
View article: Questionnaire-Based Prediction of Incident Coronary Artery Disease: Developing and Validating Machine Learning Models for Multiple Populations
Questionnaire-Based Prediction of Incident Coronary Artery Disease: Developing and Validating Machine Learning Models for Multiple Populations Open
View article: Fasting-mimicking Diet in type-2 Diabetes Reduces Myocardial Triglyceride Content
Fasting-mimicking Diet in type-2 Diabetes Reduces Myocardial Triglyceride Content Open
View article: IGF1 and Insulin Receptor Single Nucleotide Variants Associated with Response in HER2-Negative Breast Cancer Patients Treated with Neoadjuvant Chemotherapy with or without a Fasting Mimicking Diet (BOOG 2013-04 DIRECT Trial)
IGF1 and Insulin Receptor Single Nucleotide Variants Associated with Response in HER2-Negative Breast Cancer Patients Treated with Neoadjuvant Chemotherapy with or without a Fasting Mimicking Diet (BOOG 2013-04 DIRECT Trial) Open
Aim: We aimed to investigate associations between IGF1R and INSR single nucleotide variants (SNVs) and clinical response in patients with breast cancer treated with neoadjuvant chemotherapy with or without a fasting mimicking diet (FMD) fr…
View article: Fasting mimicking diet cycles versus a Mediterranean diet and cardiometabolic risk in overweight and obese hypertensive subjects: a randomized clinical trial
Fasting mimicking diet cycles versus a Mediterranean diet and cardiometabolic risk in overweight and obese hypertensive subjects: a randomized clinical trial Open
View article: Participatory Development of an Integrated, eHealth-Supported, Educational Care Pathway (Diabetes Box) for People With Type 2 Diabetes: Development and Usability Study
Participatory Development of an Integrated, eHealth-Supported, Educational Care Pathway (Diabetes Box) for People With Type 2 Diabetes: Development and Usability Study Open
Background Type 2 diabetes (T2D) tremendously affects patient health and health care globally. Changing lifestyle behaviors can help curb the burden of T2D. However, health behavior change is a complex interplay of medical, behavioral, and…
View article: Periodic use of a fasting-mimicking diet in patients with type 2 diabetes – a randomized controlled trial
Periodic use of a fasting-mimicking diet in patients with type 2 diabetes – a randomized controlled trial Open
CONTEXT: Several severely calorie-restricted continuous diets have been shown to be able to reverse the underlying pathophysiologic causes of type 2 diabetes (T2D). However, these diets can be difficult to sustain. Periodic fasting might b…
View article: Role of dietary interventions on microvascular health in South-Asian Surinamese people with type 2 diabetes in the Netherlands; a randomized controlled trial
Role of dietary interventions on microvascular health in South-Asian Surinamese people with type 2 diabetes in the Netherlands; a randomized controlled trial Open
BACKGROUND/OBJECTIVES: We investigated whether dietary interventions, i.e. a fasting mimicking diet (FMD, Prolon®) or glycocalyx mimetic supplementation (EndocalyxTM) could stabilize microvascular function in Surinamese South-As…
View article: Integration of a fasting-mimicking diet program in primary care for type 2 diabetes reduces the need for medication – a 12-month randomised controlled trial
Integration of a fasting-mimicking diet program in primary care for type 2 diabetes reduces the need for medication – a 12-month randomised controlled trial Open
Aims/hypothesis The aim of this study was to evaluate the impact on metabolic control of the periodic use of a 5-day fasting-mimicking diet (FMD) program as an adjunct to usual care in people with type 2 diabetes under regular primary care…