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View article: Bioprocess in‐line monitoring and control using Raman spectroscopy and Indirect Hard Modeling (IHM)
Bioprocess in‐line monitoring and control using Raman spectroscopy and Indirect Hard Modeling (IHM) Open
Process in‐line monitoring and control are crucial to optimize the productivity of bioprocesses. A frequently applied Process Analytical Technology (PAT) tool for bioprocess in‐line monitoring is Raman spectroscopy. However, evaluating bio…
View article: Development of the first Raman scattering thermometry during the first stage ignition in a rapid compression machine and determination of detection limits for NO-LIF
Development of the first Raman scattering thermometry during the first stage ignition in a rapid compression machine and determination of detection limits for NO-LIF Open
The interaction of recirculated NOX with two-stage fuels in the early combustion process is not fully understood, especially at lower temperatures. Recently developed kinetic combustion models try to reproduce these interactions. To valida…
View article: Interdisciplinary development of an overall process concept from glucose to 4,5-dimethyl-1,3-dioxolane via 2,3-butanediol
Interdisciplinary development of an overall process concept from glucose to 4,5-dimethyl-1,3-dioxolane via 2,3-butanediol Open
To reduce carbon dioxide emissions, carbon-neutral fuels have recently gained renewed attention. Here we show the development and evaluation of process routes for the production of such a fuel, the cyclic acetal 4,5-dimethyl-1,3-dioxolane,…
View article: The Good pH probe: Non-invasive pH in-line monitoring using Good buffers and Raman spectroscopy
The Good pH probe: Non-invasive pH in-line monitoring using Good buffers and Raman spectroscopy Open
In bioprocesses, the pH value is a critical process parameter that requires monitoring and control. For pH monitoring, potentiometric methods such as pH electrodes are state-of-the-art. Nevertheless, they are invasive and show measurement …
View article: Bioprocess in‐line monitoring using Raman spectroscopy and Indirect Hard Modeling (IHM): A simple calibration yields a robust model
Bioprocess in‐line monitoring using Raman spectroscopy and Indirect Hard Modeling (IHM): A simple calibration yields a robust model Open
To increase the process productivity and product quality of bioprocesses, the in‐line monitoring of critical process parameters is highly important. For monitoring substrate, metabolite, and product concentrations, Raman spectroscopy is a …
View article: Completely computational model setup for spectroscopic techniques: the ab initio molecular dynamics indirect hard modeling (AIMD-IHM) approach
Completely computational model setup for spectroscopic techniques: the ab initio molecular dynamics indirect hard modeling (AIMD-IHM) approach Open
The spectroscopic quantification of mixture compositions usually requires pure compounds and mixtures of known composition for calibration. Since they are not always available, methods to fill such gaps have evolved, which are, however, no…
View article: Verdampferentwicklung zur Überwindung von Engpässen in wasserbasierten Adsorptionskältemaschinen
Verdampferentwicklung zur Überwindung von Engpässen in wasserbasierten Adsorptionskältemaschinen Open
Global cooling demand continues to grow. To mitigate the resulting environmental impact, cooling solutions need to be sustainable. Adsorption chillers can provide sustainable cooling as they can employ both environmentally friendly driving…