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View article: Chronic opioid use is associated with higher antibody response to influenza vaccination in people living with HIV
Chronic opioid use is associated with higher antibody response to influenza vaccination in people living with HIV Open
Introduction We previously reported that opioid use disorder (OUD) heightens inflammation in people with HIV (PWH). Underlying inflammation is considered to be detrimental to immune responses to influenza vaccine in PWH. Here, we tested th…
View article: Barriers, beliefs, and biomedical prevention: a qualitative study of PrEP among justice-involved peripregnant women who use drugs
Barriers, beliefs, and biomedical prevention: a qualitative study of PrEP among justice-involved peripregnant women who use drugs Open
Findings underscore the urgency of designing patient-informed, context-responsive PrEP interventions that center the lived realities of CLS-involved peripregnant women who use drugs. Prioritizing long-acting PrEP options and integrating se…
View article: Implementation of Low-Dose Buprenorphine Induction at a Syringe Services Program: A Pilot Study
Implementation of Low-Dose Buprenorphine Induction at a Syringe Services Program: A Pilot Study Open
Background: Fentanyl’s penetration into the unregulated drug supply has complicated the treatment of opioid use disorder (OUD), particularly by increasing the risk of buprenorphine-precipitated opioid withdrawal (BPOW). Buprenorphine, a pa…
View article: Predictors of COVID-19 vaccine uptake and preferences for service delivery among people who inject drugs accessing a syringe service program
Predictors of COVID-19 vaccine uptake and preferences for service delivery among people who inject drugs accessing a syringe service program Open
Introduction People who inject drugs (PWID) have lower rates of COVID-19 vaccine uptake, despite being disproportionately affected by the COVID-19 pandemic. Multiple implementation adaptations have been proposed to address this gap, includ…
View article: Drug use and sexual behaviors among women who inject drugs and use a syringe services program; Miami, Florida
Drug use and sexual behaviors among women who inject drugs and use a syringe services program; Miami, Florida Open
Drawing on real-world programmatic data from routine SSP intake, this study highlights the. elevated injection and sexual health risks faced by WWID accessing a SSP. Findings support the need for gender-responsive harm reduction strategies…
View article: Rapid start with bictegravir/emtricitabine/tenofovir alafenamide (B/F/<scp>TAF</scp>) as initial treatment in people with human immunodeficiency virus‐1 (<scp>HIV</scp>‐1): A systematic literature review of clinical and patient‐reported outcomes
Rapid start with bictegravir/emtricitabine/tenofovir alafenamide (B/F/<span>TAF</span>) as initial treatment in people with human immunodeficiency virus‐1 (<span>HIV</span>‐1): A systematic literature review of clinical and patient‐reported outcomes Open
Background Treatment guidelines recommend rapid antiretroviral therapy (ART) initiation among eligible people with HIV to improve treatment outcomes and reduce HIV transmission. Bictegravir/emtricitabine/tenofovir alafenamide (B/F/TAF), an…
View article: Rapid initiation of antiretrovirals at a syringe services program for people with HIV who inject drugs
Rapid initiation of antiretrovirals at a syringe services program for people with HIV who inject drugs Open
Rapid ART initiation for PWID at an SSP was acceptable and feasible and showed preliminary effectiveness in achieving HIV viral suppression and sustaining it after transition to a traditional HIV clinic.
View article: P-444. Cerebral Small Vessel disease risk in people with HIV and substance use disorder
P-444. Cerebral Small Vessel disease risk in people with HIV and substance use disorder Open
Background Cerebral small vessel disease (CSVD) is associated with an increased risk of stroke, dementia, and death. The risk of CSVD in people with HIV (PWH) is twice the general population but the CSVD risk in PWH with substance abuse is…
View article: Long-Acting Injectable Prep for People Who Inject Drugs at a Syringe Services Program: A Qualitative Acceptability and Feasibility Study
Long-Acting Injectable Prep for People Who Inject Drugs at a Syringe Services Program: A Qualitative Acceptability and Feasibility Study Open
Although people who inject drugs (PWID) are at high risk of acquiring HIV, knowledge and uptake of pre-exposure prophylaxis (PrEP) for HIV prevention among this population remain low due to numerous psychosocial and structural barriers. Mu…
View article: Syringe services program staff and participant perspectives on changing drug consumption behaviors in response to xylazine adulteration
Syringe services program staff and participant perspectives on changing drug consumption behaviors in response to xylazine adulteration Open
Background Xylazine is an increasingly common adulterant in the North American unregulated drug supply that is associated with adverse health outcomes (e.g., skin infections, overdose). However, there are significant knowledge gaps regardi…
View article: COVID-19 vaccine implementation in a syringe services program: Experiences of frontline staff
COVID-19 vaccine implementation in a syringe services program: Experiences of frontline staff Open
Background Despite people with substance use disorders, including people who inject drugs (PWID), experiencing increased risk for COVID-19 infection and adverse outcomes, COVID-19 vaccination rates among PWID are consistently lower than th…
View article: Distributing Safer Smoking Pipes Increases Engagement with Harm Reduction Services in the United States: Findings from the National Survey of Syringe Services Programs
Distributing Safer Smoking Pipes Increases Engagement with Harm Reduction Services in the United States: Findings from the National Survey of Syringe Services Programs Open
Background In response to the recent and growing shift from injecting opioids to smoking fentanyl, an increasing number of syringe services programs (SSPs) in the USA are distributing safer smoking supplies. A recent federal ban prevents S…
View article: Decentralized HIV testing: comparing peer and mail-based distribution strategies to improve the reach of HIV self-testing among people who use drugs in Florida
Decentralized HIV testing: comparing peer and mail-based distribution strategies to improve the reach of HIV self-testing among people who use drugs in Florida Open
Introduction People who use drugs (PWUD) are at increased risk for HIV infection. HIV self-testing (HIVST) is a promising method for identifying new infections, but optimal distribution strategies remain understudied. Methods To characteri…
View article: Soluble Plasma Proteins of Tumor Necrosis Factor and Immunoglobulin Superfamilies Reveal New Insights into Immune Regulation in People with HIV and Opioid Use Disorder
Soluble Plasma Proteins of Tumor Necrosis Factor and Immunoglobulin Superfamilies Reveal New Insights into Immune Regulation in People with HIV and Opioid Use Disorder Open
People with HIV (PWH) frequently suffer from Opioid (OP) Use Disorder (OUD). In an investigation of the impact of OUD on underlying immune dysfunction in PWH, we previously reported that OP use exacerbates inflammation in virally controlle…
View article: Project CHARIOT: study protocol for a hybrid type 1 effectiveness-implementation study of comprehensive tele-harm reduction for engagement of people who inject drugs in HIV prevention services
Project CHARIOT: study protocol for a hybrid type 1 effectiveness-implementation study of comprehensive tele-harm reduction for engagement of people who inject drugs in HIV prevention services Open
Background People who inject drugs (PWID) remain a high priority population under the federal Ending the HIV Epidemic initiative with 11% of new HIV infections attributable to injection drug use. There is a critical need for innovative, ef…
View article: Financial barriers, facilitators, and strategies among syringe services programs in the U.S., and their impact on implementation and health outcomes
Financial barriers, facilitators, and strategies among syringe services programs in the U.S., and their impact on implementation and health outcomes Open
Syringe Services Programs (SSPs) provide evidence-based services like drug use equipment to prevent infectious disease, overdose prevention education, and naloxone distribution to people who use drugs (PWUD). However, inadequate funding th…
View article: Funding and Delivery of Syringe Services Programs in the United States, 2022
Funding and Delivery of Syringe Services Programs in the United States, 2022 Open
Objectives. To describe the current financial health of syringe services programs (SSPs) in the United States and to assess the predictors of SSP budget levels and associations with delivery of public health interventions. Methods. We surv…