Ayman H. El‐Deeb
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View article: Pathogenicity of Highly Pathogenic Avian Influenza Virus (H5N1) in Different Duck Breeds
Pathogenicity of Highly Pathogenic Avian Influenza Virus (H5N1) in Different Duck Breeds Open
Avian influenza viruses (AIVs) pose a global threat, with wild waterfowl serving as key reservoirs for transmission to poultry. The present study investigated the pathogenicity, viral shedding patterns, tissue distribution, and pathologica…
View article: Assessment of PPMV-1 Genotype VI Virulence in Pigeons and Chickens and Protective Effectiveness of Paramyxovirus Vaccines in Pigeons
Assessment of PPMV-1 Genotype VI Virulence in Pigeons and Chickens and Protective Effectiveness of Paramyxovirus Vaccines in Pigeons Open
Pigeon paramyxovirus serotype 1 (PPMV-1), an antigenic and host variant of avian paramyxovirus Newcastle disease virus (NDV), primarily originating from racing pigeons, has become a global panzootic. Egypt uses both inactivated PPMV-1 and …
View article: Assessment of PPMV-1 Genotype VI Virulence in Pigeons and Chickens, and Protective Effectiveness of Paramyxovirus Vaccines in Pigeons
Assessment of PPMV-1 Genotype VI Virulence in Pigeons and Chickens, and Protective Effectiveness of Paramyxovirus Vaccines in Pigeons Open
Pigeon paramyxovirus serotype 1 (PPMV-1), primarily originating from racing pigeons, has become a global panzootic, spreading to poultry and wild birds, thus posing a threat to the poultry industry. Egypt uses both inactivated pigeon param…
View article: The antiviral activities of Egyptian ethanolic propolis extract and honey bee venom against honey bees infected with multiple viruses in vitro
The antiviral activities of Egyptian ethanolic propolis extract and honey bee venom against honey bees infected with multiple viruses in vitro Open
The demand for using natural compounds as control methods for honey bee viruses have increased in recent decades. In this study, a chemical profile of honey bee venom (HBV) has been determined by FTIR spectroscopy and Egyptian ethanolic pr…
View article: Development of multiplex gold nanoparticles biosensors for ultrasensitive detection and genotyping of equine herpes viruses
Development of multiplex gold nanoparticles biosensors for ultrasensitive detection and genotyping of equine herpes viruses Open
Gold nanoparticles (GNPs) biosensors can detect low viral loads and differentiate between viruses types, enabling early diagnosis and effective disease management. In the present study, we developed GNPs biosensors with two different cappi…
View article: Prevalence of Two Distinct Genotypes of Highly Pathogenic Avian Influenza A/H5n8 Viruses in Backyard Waterfowls in Upper Egypt During 2018
Prevalence of Two Distinct Genotypes of Highly Pathogenic Avian Influenza A/H5n8 Viruses in Backyard Waterfowls in Upper Egypt During 2018 Open
H PAI viruses is a source of major concern for poultry and human health.The hemagglutinin (HA) genes of subtype H5 evolved through reassortment with various neuraminidase subtypes (1-9) to comprise AI H5NX viruses.The co-circulation of gro…
View article: SARS‐CoV‐2 infection of companion animals in Egypt and its risk of spillover
SARS‐CoV‐2 infection of companion animals in Egypt and its risk of spillover Open
Background Reverse zoonoses occur because of interactions between humans and animals. Homology of ACE‐2 cell receptors in different hosts and high mutation rate of SARS‐CoV‐2 enhance viral transmission among species. Objectives This study …
View article: Effect of honeybee venom and Egyptian propolis on the honeybee (Apis mellifera L.) health in vivo
Effect of honeybee venom and Egyptian propolis on the honeybee (Apis mellifera L.) health in vivo Open
Background Honeybees are one of the most important pollinators in the world, and their products are nowadays included in most anticancer, antiallergic, antimicrobial drugs and are included in cosmetic treatments. In the present study, hone…
View article: Mutations of the SARS-CoV-2 Spike Glycoprotein Detected in Cats and Their Effect on Its Structure and Function
Mutations of the SARS-CoV-2 Spike Glycoprotein Detected in Cats and Their Effect on Its Structure and Function Open
The high frequency of Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) mutations and homology of the Angiotensin-Converting Enzyme-2 (ACE2) cell receptors in various hosts help the virus transcend species barriers. In this stud…
View article: Pathological monitoring of visceral lesions induced by velogenic Newcastle disease in experimentally infected broiler chickens at different ages with special reference to pulmonary inflammatory cytokines expression
Pathological monitoring of visceral lesions induced by velogenic Newcastle disease in experimentally infected broiler chickens at different ages with special reference to pulmonary inflammatory cytokines expression Open
The present work aimed to study the impact of infection with a locally isolated vNDV genotype VII in commercial broiler chickens of different ages from a histopathological point of view with related changes in pulmonary cytokine expression…
View article: Discrepancies in the efficacy of H5 inactivated avian influenza vaccines in specific-pathogen-free chickens against challenge with the Egyptian H5N8 clade 2.3.4.4 Group B virus isolated in 2018
Discrepancies in the efficacy of H5 inactivated avian influenza vaccines in specific-pathogen-free chickens against challenge with the Egyptian H5N8 clade 2.3.4.4 Group B virus isolated in 2018 Open
Background and Aim: Highly pathogenic avian influenza H5N8 virus of clade 2.3.4.4 was newly emerged to Egypt and firstly detected in carcasses of wild birds in November 2016. This study assessed the protection efficacy and virus shedding r…
View article: No evidence of SARS-CoV-2 infection in <i>Rousettus aegyptiacus</i> bat in Egypt
No evidence of SARS-CoV-2 infection in <i>Rousettus aegyptiacus</i> bat in Egypt Open
Bats are considered ideal reservoirs for zoonotic viruses with emerging capabilities over the past two decades and spotted evidence points out that they may play a role as a reservoir host for SARS-CoV-2. To investigate the possible role o…
View article: Characterization of Renal Inflammatory Cytokines and Related Nephropathy in Experimentally Infected Broiler Chickens with Velogenic Newcastle Disease Virus.
Characterization of Renal Inflammatory Cytokines and Related Nephropathy in Experimentally Infected Broiler Chickens with Velogenic Newcastle Disease Virus. Open
Velogenic Newcastle disease virus (VNDV) shows systemic dissemination and it affects the histological structure and function of the kidneys.Present study is an novel attempt to correlate the changes in renal biochemical functions and gene …
View article: Protective efficacy of an inactivated vaccine against Rabbit hemorrhagic disease virus 2 prepared from a local isolate in Egypt
Protective efficacy of an inactivated vaccine against Rabbit hemorrhagic disease virus 2 prepared from a local isolate in Egypt Open
"Rabbit hemorrhagic disease is a contagious viral disease of rabbits controlled by vaccination. The present study was aimed to diagnose rabbit hemorrhagic disease from 11 infected farms from Qalubia governorate during 2019 and to prepare h…
View article: NEW INSIGHTS ON NEUROPATHOLOGICAL LESIONS PROGRESSION WITH SPECIAL EMPHASIS ON RESIDENCE OF VELOGENIC NEWCASTLE DISEASE VIRAL ANTIGEN IN THE NERVOUS SYSTEM OF EXPERIMENTALLY INFECTED BROILER CHICKENS
NEW INSIGHTS ON NEUROPATHOLOGICAL LESIONS PROGRESSION WITH SPECIAL EMPHASIS ON RESIDENCE OF VELOGENIC NEWCASTLE DISEASE VIRAL ANTIGEN IN THE NERVOUS SYSTEM OF EXPERIMENTALLY INFECTED BROILER CHICKENS Open
New castle disease virus affecting poultry industry resulting in extensive chicken mortalities and economic losses. Evaluation of distribution and severity of neuropathological lesions progressed in different areas of central nervous syste…
View article: <p>Pulmonary deregulation of expression of <em>miR-155</em> and two of its putative target genes; <em>PROS1</em> and <em>TP53INP1</em> associated with gold nanoparticles (AuNPs) administration in rat</p>
Pulmonary deregulation of expression of <em>miR-155</em> and two of its putative target genes; <em>PROS1</em> and <em>TP53INP1</em> associated with gold nanoparticles (AuNPs) administration in rat Open
Background: Gold nanoparticles (AuNPs) have been considered as an ideal candidate in various biomedical applications due to their ease of tailoring into different size, shape, and decorations with different functionalities. The current stu…
View article: Development of a recombinant Newcastle disease virus-vectored vaccine for infectious bronchitis virus variant strains circulating in Egypt
Development of a recombinant Newcastle disease virus-vectored vaccine for infectious bronchitis virus variant strains circulating in Egypt Open
Infectious bronchitis virus (IBV) causes a major disease problem for the poultry industry worldwide. The currently used live-attenuated vaccines have the tendency to mutate and/or recombine with circulating field strains resulting in the e…
View article: Development and evaluation of a multiplex reverse-transcription real-time PCR assay for detection of equine respiratory disease viruses
Development and evaluation of a multiplex reverse-transcription real-time PCR assay for detection of equine respiratory disease viruses Open
We developed a multiplex reverse-transcription real-time PCR (RT-rtPCR) assay for the simultaneous detection of the main equine respiratory viruses: equid alphaherpesviruses 1 and 4 (EHV-1, -4) and equine influenza virus (EIV; species Infl…
View article: First report of fowl adenovirus 8a from commercial broiler chickens in Egypt: molecular characterization and pathogenicity
First report of fowl adenovirus 8a from commercial broiler chickens in Egypt: molecular characterization and pathogenicity Open
This study was performed to isolate fowl adenovirus (FAdV) circulating in commercial meat-type chicken in Egypt during 2015 and to identify the pathogenicity of the isolated virus. Cloacal swabs were collected from 9 commercial broiler far…
View article: Enhanced pathogenicity of low-pathogenic H9N2 avian influenza virus after vaccination with infectious bronchitis live attenuated vaccine
Enhanced pathogenicity of low-pathogenic H9N2 avian influenza virus after vaccination with infectious bronchitis live attenuated vaccine Open
Results demonstrated the increase in pathogenicity of H9N2 AIV, especially when H9N2-infected chicks vaccinated with live IBV vaccine.
View article: IMS 1313-nanoparticle Mucosal Vaccine Enhances Immunity Against Avian Influenza and Newcastle Disease Viruses
IMS 1313-nanoparticle Mucosal Vaccine Enhances Immunity Against Avian Influenza and Newcastle Disease Viruses Open
Background and Objective: Avian influenza and Newcastle disease viruses are a continuous threat to poultry industry.Vaccines are increasingly used to control these viral infections.This study aimed to develop efficacious vaccines and vacci…
View article: Recombinase polymerase amplification assay for rapid detection of lumpy skin disease virus
Recombinase polymerase amplification assay for rapid detection of lumpy skin disease virus Open
The LSDV RPA assay is a rapid and sensitive test that could be implemented in field or at quarantine stations for the identification of LSDV infected case.
View article: Molecular Studies on Infectious Bronchitis Virus Isolated from Broiler Chickens in Damietta Governorate, Egypt
Molecular Studies on Infectious Bronchitis Virus Isolated from Broiler Chickens in Damietta Governorate, Egypt Open
Fifty-two samples of tracheal swabs and organs were collected from broiler chickens at different districts from Damietta Governorate during December 2012 to August 2014.The samples were collected from chicken farms suffered from respirator…
View article: Protective efficacy of a prime-boost protocol using H5-DNA plasmid as prime and inactivated H5N2 vaccine as the booster against the Egyptian avian influenza challenge virus
Protective efficacy of a prime-boost protocol using H5-DNA plasmid as prime and inactivated H5N2 vaccine as the booster against the Egyptian avian influenza challenge virus Open
In this study, a recombinant DNA plasmid was constructed, encoding for HA1 of a selected Egyptian H5N1 virus (isolated during the 2012 outbreaks). In the immunization and challenge experiments, SPF chickens received 1 or 2 doses of H5-DNA …