Huifang Wang
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View article: Virulence comparison and pathological impacts of three clinical Klebsiella pneumoniae isolates in a zebrafish larval model
Virulence comparison and pathological impacts of three clinical Klebsiella pneumoniae isolates in a zebrafish larval model Open
Klebsiella pneumoniae (Kp) can cause infections in communities and hospitals. After a report of a first highly virulent strain, it has now become the important pathogens that threatens human health and can often infect patients in intensiv…
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View article: The Cognitive Metonymic Motivation ofthe English There be Existential Construction
The Cognitive Metonymic Motivation ofthe English There be Existential Construction Open
The There be existential construction is an iconic English sentence pattern, which establishes a spatial cognitive framework for various nouns through the expletive subjectthereand a focus-final structure. So how is such a construction gen…
View article: Virtual brain twins for stimulation in epilepsy
Virtual brain twins for stimulation in epilepsy Open
Estimating the epileptogenic zone network (EZN) is an important part of the diagnosis of drug-resistant focal epilepsy and has a pivotal role in treatment and intervention. Virtual brain twins provide a modeling method for personalized dia…
View article: Aerosol inhalation of dimeric artesunate phospholipid-conjugated liposomes ameliorates inflammation, fibrosis, and ferroptosis in neonatal mice with hyperoxia-induced lung injury
Aerosol inhalation of dimeric artesunate phospholipid-conjugated liposomes ameliorates inflammation, fibrosis, and ferroptosis in neonatal mice with hyperoxia-induced lung injury Open
Bronchopulmonary dysplasia (BPD), a chronic lung condition that impacts preterm infants, results in persistent lung damage with limited therapeutic interventions available. Artemisinin, a bioactive compound derived from Artemisia annua, a …
View article: Assessing Functional Connectivity Dynamics During Cognitive Tasks Involving the Dorsal Stream
Assessing Functional Connectivity Dynamics During Cognitive Tasks Involving the Dorsal Stream Open
Functional connectivity and its dynamic reconfiguration during cognitive tasks offer valuable insights into the neural mechanisms underlying cognitive functions. The dorsal language stream plays a crucial role in linking auditory and visua…
View article: Research on UAV high precision autonomous intelligent detection and evaluation system for large crane equipment metal structure
Research on UAV high precision autonomous intelligent detection and evaluation system for large crane equipment metal structure Open
In order to solve the problem of remote visual detection of inaccessible parts of high-altitude structural parts of large lifting equipment, the thesis designs the upper/lower mounted UAV intelligent detection system for large cranes. The …
View article: Virtual epilepsy patient cohort: Generation and evaluation
Virtual epilepsy patient cohort: Generation and evaluation Open
Epilepsy is a prevalent brain disorder, characterized by sudden, abnormal brain activity, making it difficult to live with. One-third of people with epilepsy do not respond to anti-epileptic drugs. Drug-resistant epilepsy is treated with b…
View article: Precision non-invasive brain stimulation: an <i>in silico</i> pipeline for personalized control of brain dynamics
Precision non-invasive brain stimulation: an <i>in silico</i> pipeline for personalized control of brain dynamics Open
Objective. Non-invasive brain stimulation (NIBS) offers therapeutic benefits for various brain disorders. Personalization may enhance these benefits by optimizing stimulation parameters for individual subjects. Approach. We present a compu…
View article: Clinicopathologic Characteristics of 40 Cases of Juvenile Conjunctival Nevus
Clinicopathologic Characteristics of 40 Cases of Juvenile Conjunctival Nevus Open
Aims: Limited studies have been conducted on juvenile conjunctival nevus (JCN) in Asian populations. This study aims to investigate the clinical and pathologic characteristics of JCN cases among the Han ethnicity in northwest China, provid…
View article: Neuromodulation in Epilepsy through Temporal Interference Stimulation in Human whole-brain models
Neuromodulation in Epilepsy through Temporal Interference Stimulation in Human whole-brain models Open
View article: The Mechanistic of DCBLD2 in Inhibiting TGF-β Induced Endothelial-Mesenchymal Transition in Calcific Aortic Valve Disease
The Mechanistic of DCBLD2 in Inhibiting TGF-β Induced Endothelial-Mesenchymal Transition in Calcific Aortic Valve Disease Open
View article: Inorganic Molecule Adsorber Enhanced Hybrid Membranes for Efficient C2H2/C2H4 Separation
Inorganic Molecule Adsorber Enhanced Hybrid Membranes for Efficient C2H2/C2H4 Separation Open
View article: Inorganic Molecule Adsorber Enhanced Hybrid Membranes for Efficient C2H2/C2H4 Separation
Inorganic Molecule Adsorber Enhanced Hybrid Membranes for Efficient C2H2/C2H4 Separation Open
View article: Personalized virtual brain twins: a novel approach for better understanding and treating schizophrenia
Personalized virtual brain twins: a novel approach for better understanding and treating schizophrenia Open
View article: Principles and Operation of Virtual Brain Twins
Principles and Operation of Virtual Brain Twins Open
Current clinical methods often overlook individual variability by relying on population-wide trials, while mechanismbased trials remain underutilized in neuroscience due to the brain's complexity. This situation may change through the use …
View article: Global decoupling of functional and phylogenetic diversity in plant communities
Global decoupling of functional and phylogenetic diversity in plant communities Open
View article: Virtual brain twins for stimulation in epilepsy
Virtual brain twins for stimulation in epilepsy Open
Estimating the epileptogenic zone network (EZN) is an important part of the diagnosis of drug-resistant focal epilepsy and plays a pivotal role in treatment and intervention. Virtual brain twins, based on personalized whole brain modeling,…
View article: Virtual brain twins for stimulation in epilepsy
Virtual brain twins for stimulation in epilepsy Open
Estimating the epileptogenic zone network (EZN) is an important part of the diagnosis of drug-resistant focal epilepsy and plays a pivotal role in treatment and intervention. Virtual brain twins based on personalized whole brain modeling p…
View article: A next generation neural mass model with neuromodulation
A next generation neural mass model with neuromodulation Open
The study of brain activity and its function requires the development of computational models alongside experimental investigations to explore different effects of multiple mechanisms at play in the central nervous system. Chemical neuromo…
View article: A Nomogram Based on <scp>MRI</scp> Visual Decision Tree to Evaluate Vascular Endothelial Growth Factor in Hepatocellular Carcinoma
A Nomogram Based on <span>MRI</span> Visual Decision Tree to Evaluate Vascular Endothelial Growth Factor in Hepatocellular Carcinoma Open
Backgrounds Anti‐vascular endothelial growth factor (VEGF) therapy has been developed and recognized as an effective treatment for hepatocellular carcinoma (HCC). However, there remains a lack of noninvasive methods in precisely evaluating…
View article: Effects of the spatial resolution of the Virtual Epileptic Patient on the identification of epileptogenic networks
Effects of the spatial resolution of the Virtual Epileptic Patient on the identification of epileptogenic networks Open
Digital twins play an increasing role in clinical decision making. This study evaluates a digital brain twin approach in presurgical evaluation, the Virtual Epileptic Patient (VEP), which estimates the epileptogenic zone in patients with d…
View article: Virtual brain twins: from basic neuroscience to clinical use
Virtual brain twins: from basic neuroscience to clinical use Open
Virtual brain twins are personalized, generative and adaptive brain models based on data from an individual’s brain for scientific and clinical use. After a description of the key elements of virtual brain twins, we present the standard mo…
View article: Virtual Epilepsy Patient Cohort: Generation and Evaluation
Virtual Epilepsy Patient Cohort: Generation and Evaluation Open
View article: Brain sodium MRI-derived priors support the estimation of epileptogenic zones using personalized model-based methods in epilepsy
Brain sodium MRI-derived priors support the estimation of epileptogenic zones using personalized model-based methods in epilepsy Open
Patients presenting with drug-resistant epilepsy are eligible for surgery aiming to remove the regions involved in the production of seizure activities, the so-called epileptogenic zone network (EZN). Thus the accurate estimation of the EZ…
View article: Global patterns and environmental drivers of forest functional composition
Global patterns and environmental drivers of forest functional composition Open
Aim To determine the relationships between the functional trait composition of forest communities and environmental gradients across scales and biomes and the role of species relative abundances in these relationships. Location Global. Tim…
View article: LncRNA xist regulates sepsis associated neuroinflammation in the periventricular white matter of CLP rats by miR-122-5p/PKCη Axis
LncRNA xist regulates sepsis associated neuroinflammation in the periventricular white matter of CLP rats by miR-122-5p/PKCη Axis Open
Background Neuroinflammation is a common feature of many neurological diseases, and remains crucial for disease progression and prognosis. Activation of microglia and astrocytes can lead to neuroinflammation. However, little is known about…
View article: TREM2: Potential therapeutic targeting of microglia for Alzheimer's disease
TREM2: Potential therapeutic targeting of microglia for Alzheimer's disease Open
Alzheimer's disease (AD) is the most common neurodegenerative disease, resulting in the loss of cognitive ability and memory. However, there is no specific treatment to mechanistically inhibit the progression of Alzheimer's disease, and mo…
View article: Validation study of the Chinese version of the Community Integration Questionnaire-Revised for individuals with spinal cord injury in Mainland China
Validation study of the Chinese version of the Community Integration Questionnaire-Revised for individuals with spinal cord injury in Mainland China Open
Objective: To validate the Chinese version of the Community Integration Questionnaire-Revised (CIQ-R-C) for individuals with spinal cord injury.Design: Cross-sectional study.Setting: Shanghai Sunshine Rehabilitation Ce…
View article: [<i>Zuogui Jiangtang Jieyu</i> Decoction promotes neural stem cell self-renewal and activates Shh signaling in the hippocampal dentate gyrus of diabetic rats with depression].
[<i>Zuogui Jiangtang Jieyu</i> Decoction promotes neural stem cell self-renewal and activates Shh signaling in the hippocampal dentate gyrus of diabetic rats with depression]. Open
ZJJ can significantly improve the self-renewal ability of neural stem cells and activate Shh signaling in dentate gyrus of diabetic rats with depression.