Haofei Hu
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View article: Association between disseminated cancer and postoperative 30-day mortality in adult patients with brain tumor craniotomy
Association between disseminated cancer and postoperative 30-day mortality in adult patients with brain tumor craniotomy Open
Background Quantitative evidence on the association between disseminated cancer (DC) and 30-day postoperative mortality after tumor resection craniotomy in adults is limited. This study evaluates the association between them. Materials and…
View article: Nonlinear association between high-density lipoprotein cholesterol and carotid atherosclerosis risk in patients with type 2 diabetes: a retrospective analysis from China
Nonlinear association between high-density lipoprotein cholesterol and carotid atherosclerosis risk in patients with type 2 diabetes: a retrospective analysis from China Open
Our findings unveil an L-shaped correlation between HDL-C and CAS risk, with a distinct protective effect of HDL-C observed only below the inflection point. Our findings suggest the potential value of clinical trials aiming to elevate HDL-…
View article: Association between the ratio of triglyceride to high-density lipoprotein cholesterol (TG/HDL-c) and chronic kidney disease risk: a large-scale cross-sectional study in a Chinese population
Association between the ratio of triglyceride to high-density lipoprotein cholesterol (TG/HDL-c) and chronic kidney disease risk: a large-scale cross-sectional study in a Chinese population Open
Objective The association between lipid metabolism markers, particularly the TG/HDL-c ratio, and kidney dysfunction has not been thoroughly investigated in Chinese wellness examination cohorts. This study examines the correlation between t…
View article: Association between the aspartate aminotransferase-to-alanine aminotransferase ratio and the reversion to normoglycemia in people with impaired fasting glucose: a 5-year retrospective cohort study
Association between the aspartate aminotransferase-to-alanine aminotransferase ratio and the reversion to normoglycemia in people with impaired fasting glucose: a 5-year retrospective cohort study Open
Background Studies have shown that the aspartate aminotransferase (AST)/alanine transaminase (ALT) ratio is related to prediabetes, diabetes, and diabetes complications. However, there is limited evidence proving that the AST/ALT ratio is …
View article: Is Lipid a Missing Link Between Renal Function and Diabetes Risk? Insights from a Mediation Analysis Based on the Cohort Study
Is Lipid a Missing Link Between Renal Function and Diabetes Risk? Insights from a Mediation Analysis Based on the Cohort Study Open
Reduced renal function, as indicated by lower eGFR, is associated with increased diabetes risk. This relationship is partially mediated through lipid metabolism pathways, suggesting lipid may represent a missing link between renal function…
View article: Association between serum albumin to creatinine ratio and non-alcoholic fatty liver disease: a longitudinal cohort study in non-obese Chinese individuals
Association between serum albumin to creatinine ratio and non-alcoholic fatty liver disease: a longitudinal cohort study in non-obese Chinese individuals Open
This study demonstrates an inverse and non-linear relationship between sACR and NAFLD risk in non-obese Chinese individuals with normal LDL-c levels. The protective association is stronger when sACR exceeds 44.675. From a preventive and th…
View article: U-shaped relationship between the triglyceride glucose index and the risk of incident diabetes among MASLD adults: a retrospective cohort study
U-shaped relationship between the triglyceride glucose index and the risk of incident diabetes among MASLD adults: a retrospective cohort study Open
Background Previous research has indicated that the triglyceride glucose index (TyG-i) may serve as a potential risk factor for type 2 diabetes (T2D). However, there is a paucity of studies addressing the relationship between TyG-i and T2D…
View article: Lipoprotein combine index is associated with non-alcoholic fatty liver disease: a 5-year longitudinal cohort study in non-obese Chinese populations with normal lipids
Lipoprotein combine index is associated with non-alcoholic fatty liver disease: a 5-year longitudinal cohort study in non-obese Chinese populations with normal lipids Open
Objective Current evidence concerning the association between lipoprotein combine index (LCI) and Non-alcoholic fatty liver disease (NAFLD) in non-obese people remains limited. This 5-year longitudinal cohort study aimed to explore the con…
View article: The role of B lymphocyte subsets in nephrotic syndrome: functions, mechanisms, clinical significance and future perspectives
The role of B lymphocyte subsets in nephrotic syndrome: functions, mechanisms, clinical significance and future perspectives Open
B lymphocytes play a critical role in the pathogenesis of nephrotic syndrome (NS). This comprehensive review explores the phenotypic characteristics, pathogenic mechanisms, and clinical translational value of B cell subsets in different ty…
View article: Clinical Value of Metagenomic Next‐Generation Sequencing in Early Diagnosis of Peritoneal Dialysis‐Associated Peritonitis: A Randomised Controlled Observational Trial
Clinical Value of Metagenomic Next‐Generation Sequencing in Early Diagnosis of Peritoneal Dialysis‐Associated Peritonitis: A Randomised Controlled Observational Trial Open
Aim While metagenomic next‐generation sequencing (mNGS) is a high‐throughput diagnostic tool capable of rapidly and accurately identifying pathogenic microorganisms, predicting their antibiotic resistance/susceptibility profiles, its clini…
View article: Early dynamic changes in platelet counts and 28-day mortality in sepsis patients: a retrospective cohort study using dynamic latent class model and generalized additive mixture model analysis
Early dynamic changes in platelet counts and 28-day mortality in sepsis patients: a retrospective cohort study using dynamic latent class model and generalized additive mixture model analysis Open
Objective This study investigates the relationship between early dynamic changes in platelet (PLT) counts and 28-day mortality in Chinese patients with sepsis, addressing the limitations of previous studies that focused on single baseline …
View article: Non-linear relationship between the hepatic steatosis index and glycemic progression: evidence from a large-scale retrospective cohort study in a Chinese population
Non-linear relationship between the hepatic steatosis index and glycemic progression: evidence from a large-scale retrospective cohort study in a Chinese population Open
Elevated HSI demonstrated a positive, non-linear correlation with the risk of glycemic progression, suggesting that maintaining lower HSI levels may mitigate the risk of developing glycemic progression.
View article: Body mass index and mortality after elective open abdominal aortic aneurysm repair in a fifteen year multicenter cohort study
Body mass index and mortality after elective open abdominal aortic aneurysm repair in a fifteen year multicenter cohort study Open
The correlation between body mass index (BMI) and the outcomes for patients receiving surgical intervention for abdominal aortic aneurysm (AAA) is still debated. Consequently, this study seeks to investigate the association between BMI and…
View article: The non-linear association between remnant cholesterol/high-density lipoprotein cholesterol ratio and diabetic retinopathy: a cross-sectional study in type 2 diabetic patients
The non-linear association between remnant cholesterol/high-density lipoprotein cholesterol ratio and diabetic retinopathy: a cross-sectional study in type 2 diabetic patients Open
This study contributes valuable insights into the intricate association between the RC/HDL-c ratio and both DR and PDR in individuals diagnosed with T2DM. By identifying a non-linear association, our findings enhance the existing knowledge…
View article: High incidence of idiopathic membranous nephropathy in the Zhuang population: A comparative study of two centers in Southern China
High incidence of idiopathic membranous nephropathy in the Zhuang population: A comparative study of two centers in Southern China Open
Background: Idiopathic membranous nephropathy is a common cause of nephrotic syndrome in adults with increasing incidence in southern China. This study compared Idiopathic membranous nephropathy prevalence, clinicopathological features, an…
View article: Correlation between serum complement component 4 levels and tubular atrophy in patients with lupus nephritis
Correlation between serum complement component 4 levels and tubular atrophy in patients with lupus nephritis Open
Serum C4 levels demonstrate a significant correlation with the presence of tubular atrophy in patients diagnosed with LN.
View article: Sex differences in the relationship between body mass index in Chinese adolescents and future risk of hypertension: a decade-long cohort study
Sex differences in the relationship between body mass index in Chinese adolescents and future risk of hypertension: a decade-long cohort study Open
Among Chinese adolescent males, there was a positive dose-response relationship between BMI and future hypertension risk. In adolescent females, a specific nonlinear association with a threshold effect (inflection point: 24.11 kg/m²) was o…
View article: Incidence and pathological features of IgA nephropathy before and during the COVID-19 pandemic
Incidence and pathological features of IgA nephropathy before and during the COVID-19 pandemic Open
IgA nephropathy (IgAN) imposes a substantial burden of illness and death. However, a systematic evaluation of the impact of the COVID-19 pandemic on the incidence and pathology of IgAN has yet to be performed. In this study, we analyzed ki…
View article: Mean arterial pressure at the initiation of continuous renal replacement therapy as a prognostic indicator in patients with acute kidney injury
Mean arterial pressure at the initiation of continuous renal replacement therapy as a prognostic indicator in patients with acute kidney injury Open
The higher the MAP before CRRT is, the lower the 28- and 90-day mortality of critically ill patients with AKI who are treated with CRRT.
View article: Association between triglyceride to high-density lipoprotein cholesterol ratio and microalbuminuria in the Chinese population
Association between triglyceride to high-density lipoprotein cholesterol ratio and microalbuminuria in the Chinese population Open
The evidence for the association between the triglyceride (TG) to high-density lipoprotein cholesterol (HDL-c) ratio and the risk of developing microalbuminuria is still limited in the Chinese population. Therefore, our research will endea…
View article: Non-linear relationship between the atherogenic index of plasma and ischemic stroke in the diabetic population in ICU: A multicenter retrospective cohort study
Non-linear relationship between the atherogenic index of plasma and ischemic stroke in the diabetic population in ICU: A multicenter retrospective cohort study Open
Objectives The Atherogenic Index of Plasma (AIP) value is relationship with the risk of atherosclerosis, a known risk factor for cardiovascular events. However, studies on the correlation between AIP value and ischemic stroke (IS) in the d…