Explanipedia

Bilateral Cerebellar Intermittent Theta Burst Stimulation Enhances Swallowing Function and Cortical Reorganization in Patients With Subacute Stroke: A Randomized Single-Blind Controlled Trial Open

Haobo Zhang, Jiun Yan Tan, Lu Wei, Junting Han, Shanshan Kong , et al. · 2025

The Chinese Clinical Trial Registry number for the study is ChiCTR2300071303.

Analysis of the Interaction Between the Attenuated HSV-1 Strain M6 and Macrophages Indicates Its Potential as an Effective Vaccine Immunogen Open

Zhenxiao Zhang, Xiaohong Ren, Ying Zhang, Jingjing Zhang, Xinghang Li , et al. · 2025

Herpes simplex virus type 1 (HSV-1) is a very concerning pathogen due to its ability to persist in the host’s nervous system and continuously interfere with the immune system, which complicates treatment. Therefore, the development of an e…

Electronic Structure Tunable Metallosupramolecular Polymers as Bifunctional Electrocatalysts for Rechargeable Zn‐Air Battery Open

Rui‐Lin Chai, Shenghui Han, Liwei Wang, Shenghua Li, Hui Pan , et al. · 2025

Metallosupramolecular polymers (MSPs) have shown great potential in the area of oxygen electrocatalysis due to their tunable electronic structure, and predictable coordination environment. Further exploration of structure−performance relat…

Immune Response Elicited by Recombinant Adenovirus-Delivered Glycoprotein B and Nucleocapsid Protein UL18 and UL25 of HSV-1 in Mice Open

Haobo Zhang, Qi Li, Yun Liao, Danjing Ma, Fengyuan Zeng , et al. · 2024

Due to the complex pathogenic and immune escape mechanisms of herpes simplex virus type 1 (HSV-1), especially the failure of induced immune responses to block the initial cell-to-cell transmission of the virus from skin cells to neurons, t…

Development and evaluation of a triplex droplet digital PCR method for differentiation of M. tuberculosis, M. bovis and BCG Open

Yao Qu, Mengda Liu, Xiangxiang Sun, Yongxia Liu, Jianzhu Liu , et al. · 2024

Introduction Tuberculosis, caused by Mycobacterium tuberculosis complex (MTBC), remains a global health concern in both human and animals. However, the absence of rapid, accurate, and highly sensitive detection methods to differentiate the…

Behavioral and Transcriptomic Analyses in the Indoxacarb Response of a Non-Target Damselfly Species Open

Bin Jiang, Wei Wang, Yu Yao, Haobo Zhang, Yongmei Zhang , et al. · 2024

Ischnura senegalensis, which widely spreads in paddy fields, has the potential to be used as a natural predator of insect pests. However, the application of insecticides in the field could pose a threat to the survival of I. senegalensis. …

MORN2 regulates the morphology and energy metabolism of mitochondria and is required for male fertility in mice Open

Yining Liu, Tongtong Li, Mingze Shi, Yanling Wan, Hanzhen Li , et al. · 2024

Noninvasive serum N-glycans associated with ovarian cancer diagnosis and precancerous lesion prediction Open

Si Liu, Chang Tu, Haobo Zhang, Hanhui Huang, Yuanyuan Liu , et al. · 2024

Heterologous Booster Immunization Based on Inactivated SARS-CoV-2 Vaccine Enhances Humoral Immunity and Promotes BCR Repertoire Development Open

Xinghang Li, Fengyuan Zeng, Rong Yue, Danjing Ma, Ziyan Meng , et al. · 2024

Recent studies have indicated that sequentially administering SARS-CoV-2 vaccines can result in increased antibody and cellular immune responses. In this study, we compared homologous and heterologous immunization strategies following two …

Deep Learning enables reliable and comprehensive profiling of invertible promoters in microbes Open

Jiejie Wen, Haobo Zhang, Dongliang Chu, Xiaoke Chen, Yuxue Li , et al. · 2023

Invertible promoters (invertons) are regulatory elements found in bacteria, with inverted repeat sequences at both ends, leading to alternating changes in the expression of the regulated genes. Since invertons were present in more than 20%…

NhaA facilitates the maintenance of bacterial envelope integrity and the evasion of complement attack contributing to extraintestinal pathogenic <i>Escherichia coli</i> virulence Open

Mao Zhao, Haobo Zhang, Wentong Cai, Yan Yang, Xinyang Zhang , et al. · 2023

Extraintestinal pathogenic Escherichia coli (ExPEC) is responsible for severe bloodstream infections in humans and animals. However, the mechanisms underlying ExPEC’s serum resistance remain incompletely understood. Through the transposon-…

Mechanical property analysis and rationality study of new offshore floating wind power photovoltaic structure Open

Haobo Zhang, Chenrui Su · 2023

Nowadays, the problem of energy deficiency is getting more and more serious. The search for clean and sustainable energy is of great importance. The research topic of this article is the construction of an offshore floating structure which…

The virulence regulator AbsR in avian pathogenic has pleiotropic effects on bacterial physiology Open

Dongfang Zhao, Haobo Zhang, Xinyang Zhang, Fengwei Jiang, Yijing Li , et al. · 2023

Avian pathogenic Escherichia coli (APEC) belonging to extraintestinal pathogenic E. coli (ExPEC) can cause severe infections in extraintestinal tissues in birds and humans, such as the lungs and blood. MprA (microcin production regulation,…

The impact of the COVID-19 pandemic on semen quality of uninfected men Open

Wenjun Zhang, Li Wang, Jiwei Sun, Linlin Cui, Haobo Zhang , et al. · 2023

Study of the Effects of Several SARS-CoV-2 Structural Proteins on Antiviral Immunity Open

Rong Yue, Fengyuan Zeng, Danjing Ma, Ziyan Meng, Xinghang Li , et al. · 2023

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Spike (S) protein is a critical viral antigenic protein that enables the production of neutralizing antibodies, while other structural proteins, including the membrane (M), n…

Sirtuin 3 regulation: a target to alleviate β-hydroxybutyric acid-induced mitochondrial dysfunction in bovine granulosa cells Open

Shanjiang Zhao, Jianfei Gong, Yi Wang, Nuo Heng, Huan Wang , et al. · 2023

Density Gradient Centrifugation Alone or the Combination of DGC with Annexin V Magnetic‐Activated Cell Sorting Prior to Cryopreservation Enhances the Postthaw Quality of Sperm from Infertile Male Patients with Poor Sperm Quality Open

Sijie Yang, Xuan Gao, Taijian Zhang, Feifei Cai, Haobo Zhang · 2023

Objective . To examine whether density gradient centrifugation (DGC) alone or its combination with annexin V magnetic‐activated cell sorting (DGC‐MACS) can be used to process semen samples from infertile male patients with poor sperm quali…

Does ICSI outcome in obstructive azoospermia differ according to the origin of retrieved spermatozoa or the cause of epididymal obstruction? A comparative study Open

Xiaochen Yu, Shaoming Lu, Mingzhen Yuan, Gang Ma, Xiao Li , et al. · 2022

Purpose To determine whether ICSI outcomes are affected by sperm source or genital tract inflammatory status. Methods A retrospective cohort study was conducted in all consecutive obstructive azoospermia patients who underwent testicular s…

The comparative effects of oral Chinese patent medicines combined with western medicine in stable angina: A systematic review and network meta-analysis of 179 trials Open

Peiying Huang, Zhishang Li, Li Chen, Jing Zeng, Shuai Zhao , et al. · 2022

Background: Stable angina is a common condition with high morbidity and mortality rates. It has been reported that combining oral Chinese patent medicines (OCPMs) and Western medicine (WM) could potentially achieve a better effect than WM …

Mitofusins: from mitochondria to fertility Open

Shanjiang Zhao, Nuo Heng, Huan Wang, Haoyu Wang, Haobo Zhang , et al. · 2022

Germ cell formation and embryonic development require ATP synthesized by mitochondria. The dynamic system of the mitochondria, and in particular, the fusion of mitochondria, are essential for the generation of energy. Mitofusin1 and mitofu…

A Five-Dimensional Network Meta-Analysis of Chinese Herbal Injections for Treating Acute Tonsillitis Combined With Western Medicine Open

Peiying Huang, Yin Li, Bixuan Huang, Shuai Zhao, Li Chen , et al. · 2022

Background: Acute tonsillitis has high morbidity. Chinese herbal injections (CHIs) were reported to be useful in treating acute tonsillitis and might reduce the probability of antibiotic resistance. Nevertheless, the optimal strategy for c…

Industrial Robot Vibration Anomaly Detection Based on Sliding Window One-Dimensional Convolution Autoencoder Open

Zhidan Zhong, Yao Zhao, Aoyu Yang, Haobo Zhang, Donghao Qiao , et al. · 2022

Model-based methods can be used to detect anomalies in industrial robots, but they require a high level of expertise and are therefore difficult to implement. The lack of sufficient data on the anomalous operation of industrial robots limi…

ICSI outcomes for infertile men with severe or complete asthenozoospermia Open

Tong Chen, Demin Fan, Xianlong Wang, Changlin Mao, Yaru Chu , et al. · 2022

Background Severe or complete asthenozoospermia is a rare entity that can lead to male infertility. In this study, we explored whether different extents of severe or complete asthenozoospermia could affect intracytoplasmic sperm injection …

Robotic natural orifice specimen extraction surgery for colorectal cancer: an open-label, single-arm study Open

Yun Zhong, Haobo Zhang, Rui Luo, Taiyuan Li, Dongning Liu · 2022

Background: Robotic natural orifice specimen extraction surgery (NOSES) is a minimally invasive surgery for colorectal cancer patients. As an emerging procedure, its safety and feasibility require thorough investigation. This study aimed t…

Jiaxian magnetics data Open

Wang Xiaoxue, Junsheng Nie, Thomas Stevens, Haobo Zhang, Wenjiao Xiao · 2022