Haowei Ye
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View article: The emergence and spread of blaNDM-1, blaKPC-2, mcr-10 genes, and the tmexCD2-toprJ2 gene cluster in extensively drug-resistant clinical Raoultella ornithinolytica
The emergence and spread of blaNDM-1, blaKPC-2, mcr-10 genes, and the tmexCD2-toprJ2 gene cluster in extensively drug-resistant clinical Raoultella ornithinolytica Open
Background Raoultella ornithinolytica is an infrequent opportunistic pathogen capable of causing multi-site infections and frequently harboring a broad array of resistance determinants, thereby complicating antimicrobial therapy. Here we r…
View article: Unravelling tandem repeat-mediated mutagenesis drive rapid diversification of KPC enzymes: emergence of blaKPC-263 and enhanced resistance to ceftazidime-avibactam
Unravelling tandem repeat-mediated mutagenesis drive rapid diversification of KPC enzymes: emergence of blaKPC-263 and enhanced resistance to ceftazidime-avibactam Open
This work was funded by the National Key R&D Programme of China (2023YFC2308400); National Natural Science Foundation of China (82072314); Shandong Provincial Laboratory Project (SYS202202); Zhejiang Province Leading Geese Plan (2025C04013…
View article: Emergence of ST11 <i>Klebsiella pneumoniae</i> co-carrying <i>bla</i> <sub>KPC-2</sub> and <i>bla</i> <sub>IMP-8</sub> on conjugative plasmids
Emergence of ST11 <i>Klebsiella pneumoniae</i> co-carrying <i>bla</i> <sub>KPC-2</sub> and <i>bla</i> <sub>IMP-8</sub> on conjugative plasmids Open
Klebsiella pneumoniae is a major pathogen with substantial antimicrobial resistance driven by β-lactamase production. The co-existence of carbapenemase genes bla KPC-2 and bla IMP-8 in the prevalent K. pneumoniae clone is rare and poses si…
View article: Effects of Research and Development Subsidies on Research and Development Investment and Firm Performance: Evidence From High-Tech Firms in China
Effects of Research and Development Subsidies on Research and Development Investment and Firm Performance: Evidence From High-Tech Firms in China Open
Over the past decade, the Chinese government has actively promoting research and development (R&D) in high-tech industries to foster scientific and technological innovation and address economic slowdown. Against this backdrop, this study e…
View article: Coexistence of blaNDM-1, mcr-1 and blaCTX-M-199 in an ST499 multidrug resistant Klebsiella pneumoniae Isolate
Coexistence of blaNDM-1, mcr-1 and blaCTX-M-199 in an ST499 multidrug resistant Klebsiella pneumoniae Isolate Open
The coexistence of multiple resistance genes within a single bacterial strain presents a significant public health challenge, as it complicates treatment options and accelerates the spread of multidrug resistance. While the co-occurrence o…
View article: Genomic and phenotypic insights into ST164 blaNDM-1-positive Acinetobacter baumannii from intestinal colonization in China
Genomic and phenotypic insights into ST164 blaNDM-1-positive Acinetobacter baumannii from intestinal colonization in China Open
View article: Genomic epidemiology and characterization of difficult-to-treat resistant Pseudomonas aeruginosa isolates co-harboring blaOXA-50 and crpP causing bronchiectasis
Genomic epidemiology and characterization of difficult-to-treat resistant Pseudomonas aeruginosa isolates co-harboring blaOXA-50 and crpP causing bronchiectasis Open
View article: Genome Characteristic of NDM-5-Producing Klebsiella Quasipneumoniae and Klebsiella Pneumoniae in China
Genome Characteristic of NDM-5-Producing Klebsiella Quasipneumoniae and Klebsiella Pneumoniae in China Open
The global dissemination of carbapenem-resistant Enterobacteriaceae poses a significant threat to public health. In this study, we identified two clinical Klebsiella isolates, K. quasipneumoniae ACESH02628 and K. pneumonia…
View article: Research on the Impact of Consumer Preference on the Profit of Catering Enterprises
Research on the Impact of Consumer Preference on the Profit of Catering Enterprises Open
In recent years, with the increasing improvement of the living standards, people's requirements for catering become higher and higher, which has also led to an increasing number of factors affecting the profit of catering enterprises. Howe…