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View article: A Plasma-based Deep Proteomic Platform for Early-Stage Breast Cancer Detection
A Plasma-based Deep Proteomic Platform for Early-Stage Breast Cancer Detection Open
Despite the widespread use of mammography as the standard of care for breast cancer screening, its accuracy remains limited for select patient populations, such as women with high breast density. Liquid biopsy-based tests offer an accessib…
View article: A Plasma-based Deep Proteomic Platform for Early-Stage Breast Cancer Detection
A Plasma-based Deep Proteomic Platform for Early-Stage Breast Cancer Detection Open
Despite the widespread use of mammography as the standard of care for breast cancer screening, its accuracy remains limited for select patient populations, such as women with high breast density. Liquid biopsy-based tests offer an accessib…
View article: Rapid, high-throughput isolation of tumor specific small extracellular vesicles using radial flow microfluidic chip with IEDDA chemistry (ExoOnco ChipEpCAM−TCO)
Rapid, high-throughput isolation of tumor specific small extracellular vesicles using radial flow microfluidic chip with IEDDA chemistry (ExoOnco ChipEpCAM−TCO) Open
Extracellular vesicles (sEVs) are promise as biomarkers for early cancer diagnostics and prognostics. Immunoaffinity-based isolation techniques using antibodies for specific sEV surface proteins offer high specificity and purity. However, …
View article: Development of Analytical Techniques for the Characterization of Circulating Tumor Cells and their Immune Interactions
Development of Analytical Techniques for the Characterization of Circulating Tumor Cells and their Immune Interactions Open
In cancer diagnostics, liquid biopsies, which isolate and analyze biomarkers of disease from biological fluids, offer an attractive alternative to traditional tissue-biopsy techniques. Circulating tumor cells (CTCs) have emerged as an info…
View article: Integrated Workflow for the Label-Free Isolation and Genomic Analysis of Single Circulating Tumor Cells in Pancreatic Cancer
Integrated Workflow for the Label-Free Isolation and Genomic Analysis of Single Circulating Tumor Cells in Pancreatic Cancer Open
As pancreatic cancer is the third deadliest cancer in the U.S., the ability to study genetic alterations is necessary to provide further insight into potentially targetable regions for cancer treatment. Circulating tumor cells (CTCs) repre…
View article: What's in a vein?
What's in a vein? Open
Central MessageThis review examines the basic science of circulating tumor cells in NSCLC. We review a study from Wei et al on the impact of surgical technique on CTCs.See Commentaries on pages 354 and 356.Feature Editor Note—In this Invit…
View article: Software tools for quantum control: Improving quantum computer\n performance through noise and error suppression
Software tools for quantum control: Improving quantum computer\n performance through noise and error suppression Open
Manipulating quantum computing hardware in the presence of imperfect devices\nand control systems is a central challenge in realizing useful quantum\ncomputers. Susceptibility to noise limits the performance and capabilities of\nnoisy inte…