Harrison R. Berger
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View article: Supplementary Table 1 from Endoglin-Directed CAR T Cells Comprehensively Target Tumors in Advanced Sarcomas
Supplementary Table 1 from Endoglin-Directed CAR T Cells Comprehensively Target Tumors in Advanced Sarcomas Open
List of antibodies and reagents used in the study.
View article: Supplementary Figure 2 from Endoglin-Directed CAR T Cells Comprehensively Target Tumors in Advanced Sarcomas
Supplementary Figure 2 from Endoglin-Directed CAR T Cells Comprehensively Target Tumors in Advanced Sarcomas Open
ENG CAR design and molecular modeling.
View article: Supplementary Figure 3 from Endoglin-Directed CAR T Cells Comprehensively Target Tumors in Advanced Sarcomas
Supplementary Figure 3 from Endoglin-Directed CAR T Cells Comprehensively Target Tumors in Advanced Sarcomas Open
Activation induced cytokine release and proliferation of ENG CAR-T.
View article: Supplementary Figure 5 from Endoglin-Directed CAR T Cells Comprehensively Target Tumors in Advanced Sarcomas
Supplementary Figure 5 from Endoglin-Directed CAR T Cells Comprehensively Target Tumors in Advanced Sarcomas Open
Efficacy of ENG CAR-T in orthotopic xenograft models of sarcoma.
View article: Supplementary Figure 6 from Endoglin-Directed CAR T Cells Comprehensively Target Tumors in Advanced Sarcomas
Supplementary Figure 6 from Endoglin-Directed CAR T Cells Comprehensively Target Tumors in Advanced Sarcomas Open
The c-SN6j/TRC105 antibody does not recognize murine or rhesus endoglin.
View article: Supplementary Figure 4 from Endoglin-Directed CAR T Cells Comprehensively Target Tumors in Advanced Sarcomas
Supplementary Figure 4 from Endoglin-Directed CAR T Cells Comprehensively Target Tumors in Advanced Sarcomas Open
Binding of recombinant ENG to CAR-T.
View article: Data from Endoglin-Directed CAR T Cells Comprehensively Target Tumors in Advanced Sarcomas
Data from Endoglin-Directed CAR T Cells Comprehensively Target Tumors in Advanced Sarcomas Open
There are limited therapeutic options for patients with advanced sarcomas, which leads to dismal outcomes for children and adults. Although chimeric antigen receptor (CAR) T cells hold promise for treating advanced sarcomas, this approach …
View article: Supplementary Table 2 from Endoglin-Directed CAR T Cells Comprehensively Target Tumors in Advanced Sarcomas
Supplementary Table 2 from Endoglin-Directed CAR T Cells Comprehensively Target Tumors in Advanced Sarcomas Open
Rhabdomyosarcoma cell lines with transcript expression of ENG, CD44, CD70, and CD90 from the CCLE public release 24Q4 with fusion status and histology.
View article: Supplementary Figure 1 from Endoglin-Directed CAR T Cells Comprehensively Target Tumors in Advanced Sarcomas
Supplementary Figure 1 from Endoglin-Directed CAR T Cells Comprehensively Target Tumors in Advanced Sarcomas Open
ENG expression in sarcoma tissues and cell lines.
View article: Molecular dynamics at immune synapse lipid rafts influence the cytolytic behavior of CAR T cells
Molecular dynamics at immune synapse lipid rafts influence the cytolytic behavior of CAR T cells Open
Chimeric antigen receptor T cells (CART) targeting CD19 through CD28.ζ signaling induce rapid lysis of leukemic blasts, contrasting with persistent tumor control exhibited by 4-1BB.ζ-CART. We reasoned that molecular dynamics at the CART im…