Harrshavasan Congivaram
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View article: TMET-14. <i>NOTCH3</i> mediates metabolic reprogramming and ferroptosis resistance in meningiomas
TMET-14. <i>NOTCH3</i> mediates metabolic reprogramming and ferroptosis resistance in meningiomas Open
NOTCH3 is increasingly implicated for its oncogenic role in many malignancies, including meningiomas. While prior work has linked NOTCH3 expression to higher-grade meningiomas and radiation therapy resistance, the metabolic phenotype of NO…
View article: NOTCH3 drives fatty acid oxidation and ferroptosis resistance in aggressive meningiomas
NOTCH3 drives fatty acid oxidation and ferroptosis resistance in aggressive meningiomas Open
Purpose NOTCH3 is increasingly implicated for its oncogenic role in many malignancies, including meningiomas. While prior work has linked NOTCH3 expression to higher-grade meningiomas and treatment resistance, the metabolic phenotype of NO…
View article: Primary papillary epithelial tumor of the sella harboring an EZH2 Y646F mutation
Primary papillary epithelial tumor of the sella harboring an EZH2 Y646F mutation Open
View article: NOTCH3 Drives Fatty Acid Oxidation and Ferroptosis Resistance in Aggressive Meningiomas
NOTCH3 Drives Fatty Acid Oxidation and Ferroptosis Resistance in Aggressive Meningiomas Open
PURPOSE NOTCH3 is increasingly implicated for its oncogenic role in many malignancies, including meningiomas. While prior work has linked NOTCH3 expression to higher-grade meningiomas and treatment resistance, the metabolic phenotype of NO…
View article: Assessment of “Zero-Shot” General Purpose Segmentation Models: An Analysis of the Meta “Segment Anything Model” on Meningioma MRI
Assessment of “Zero-Shot” General Purpose Segmentation Models: An Analysis of the Meta “Segment Anything Model” on Meningioma MRI Open
SAM2 demonstrated reasonable zero-shot segmentation performance on meningioma MRIs, with observable improvements seen with contour-based prompting and directional ensembling. These results suggest that zero-shot segmentation models, with s…