Harry E. Prince
YOU?
Author Swipe
View article: Relationship Between HSV-1 Serostatus and HSV-2 IgG Confirmation Results using an Inhibition Assay
Relationship Between HSV-1 Serostatus and HSV-2 IgG Confirmation Results using an Inhibition Assay Open
Background: Approximately 2% of HerpeSelect Herpes Simples Virus type 2 (HSV-2) IgG enzyme immunoassay (screen assay) sera positive samples do not confirm using an HSV-2 IgG inhibition assay. Of these, roughly 1.33% are confirmed negative …
View article: Concordance of Results by Three Chagas Disease Antibody Assays in U.S. Clinical Specimens
Concordance of Results by Three Chagas Disease Antibody Assays in U.S. Clinical Specimens Open
Confirmed diagnosis of chronic Trypanosoma cruzi infection requires positive results by two distinct serological tests (1, 2). Test performance varies by assay and geographic origin of the infection (3–5). Previously, we reported the perfo…
View article: Duration of West Nile Virus IgM Antibodies up to 81 Months Following West Nile Virus Disease Onset
Duration of West Nile Virus IgM Antibodies up to 81 Months Following West Nile Virus Disease Onset Open
West Nile virus (WNV) IgM antibodies typically indicate a recent infection. However, WNV IgM antibodies can remain detectable for months to years following illness onset. We found that 23% (11/47) of samples tested with a WNV ELISA and 43%…
View article: Detection of SARS-CoV-2 IgG Targeting Nucleocapsid or Spike Protein by Four High-Throughput Immunoassays Authorized for Emergency Use
Detection of SARS-CoV-2 IgG Targeting Nucleocapsid or Spike Protein by Four High-Throughput Immunoassays Authorized for Emergency Use Open
A total of 1,200 serum samples that were tested for SARS-CoV-2 IgG antibody using the Abbott Architect immunoassay targeting the nucleocapsid protein were run in 3 SARS-CoV-2 IgG immunoassays targeting spike proteins (DiaSorin Liaison, Ort…
View article: Multilaboratory Comparison of Pneumococcal Multiplex Immunoassays Used in Immunosurveillance of Streptococcus pneumoniae across Europe
Multilaboratory Comparison of Pneumococcal Multiplex Immunoassays Used in Immunosurveillance of Streptococcus pneumoniae across Europe Open
Serology of Streptococcus pneumoniae is challenging due to existence of multiple clinically relevant serotypes and the introduction of multivalent vaccines in national immunization programs. Multiplex immunoassays (MIAs) are applied as hig…
View article: Evaluation of Two Enzyme-Linked Immunosorbent Assay Kits for Chikungunya Virus IgM Using Samples from Deceased Organ and Tissue Donors
Evaluation of Two Enzyme-Linked Immunosorbent Assay Kits for Chikungunya Virus IgM Using Samples from Deceased Organ and Tissue Donors Open
The identification of nearly 3,500 cases of chikungunya virus (CHIKV) infection in U.S. residents returning in 2014 and 2015 from areas in which it is endemic has raised concerns within the transplant community that, should recently infect…
View article: Evaluation of Commercial Assays for Single-Point Diagnosis of Pertussis in the US
Evaluation of Commercial Assays for Single-Point Diagnosis of Pertussis in the US Open
Seroassays varied substantially under both analytical and clinical parameters; however, those that were calibrated to a reference standard were highly accurate. Our findings support incorporation of calibrated pertussis seroassays to the p…
View article: Comparison of Enzyme Immunoassays for Detection of Antibodies to Hepatitis D Virus in Serum
Comparison of Enzyme Immunoassays for Detection of Antibodies to Hepatitis D Virus in Serum Open
Serology remains critical for diagnosing hepatitis D virus (HDV) infection, which affects 15 to 20 million people worldwide, but the literature on characterizing commercial enzyme immunoassays (EIAs) dates back to 15 years ago. We evaluate…
View article: Duration of Dengue Viremia in Blood Donors and Relationships Between Donor Viremia, Infection Incidence and Clinical Case Reports During a Large Epidemic
Duration of Dengue Viremia in Blood Donors and Relationships Between Donor Viremia, Infection Incidence and Clinical Case Reports During a Large Epidemic Open
These parameters allow projections of dengue incidence from donor NAT yield data and vice versa, and suggest that viremic donations will be rare relative to clinical disease cases.
View article: Evaluation of a Multiplex Bead Immunoassay for Determination of Immune Status to Varicella-Zoster Virus in Medical Center Students and Employees
Evaluation of a Multiplex Bead Immunoassay for Determination of Immune Status to Varicella-Zoster Virus in Medical Center Students and Employees Open
This study evaluated an enzyme immunoassay, a multiplex bead immunoassay (MBIA), and the anticomplement immunofluorescence (ACIF) test for detecting varicella-zoster virus IgG antibodies in sera from medical center students and employees. …