Harry Jubb
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View article: PDBe-KB: a community-driven resource for structural and functional annotations
PDBe-KB: a community-driven resource for structural and functional annotations Open
The Protein Data Bank in Europe-Knowledge Base (PDBe-KB, https://pdbe-kb.org) is a community-driven, collaborative resource for literature-derived, manually curated and computationally predicted structural and functional annotations of mac…
Understanding the impacts of missense mutations on structures and functions of human cancer-related genes: A preliminary computational analysis of the COSMIC Cancer Gene Census Open
Genomics and genome screening are proving central to the study of cancer. However, a good appreciation of the protein structures coded by cancer genes is also invaluable, especially for the understanding of functions, for assessing liganda…
View article: COSMIC: the Catalogue Of Somatic Mutations In Cancer
COSMIC: the Catalogue Of Somatic Mutations In Cancer Open
This FAIRsharing record describes: The Catalogue of Somatic Mutations in Cancer (COSMIC) is a database of manually-curated somatic mutation information relating to human cancers. The COSMIC database combines manually-curated data and genom…
Mutations at protein-protein interfaces: Small changes over big surfaces have large impacts on human health Open
Many essential biological processes including cell regulation and signalling are mediated through the assembly of protein complexes. Changes to protein-protein interaction (PPI) interfaces can affect the formation of multiprotein complexes…
View article: COSMIC: somatic cancer genetics at high-resolution
COSMIC: somatic cancer genetics at high-resolution Open
COSMIC, the Catalogue of Somatic Mutations in Cancer (http://cancer.sanger.ac.uk) is a high-resolution resource for exploring targets and trends in the genetics of human cancer. Currently the broadest database of mutations in cancer, the i…