Harsh Desai
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View article: Cervical Internal Carotid Artery Plaque Composition and Chronic White Matter Disease in Patients with Noncardioembolic Stroke: A Multicenter Analysis
Cervical Internal Carotid Artery Plaque Composition and Chronic White Matter Disease in Patients with Noncardioembolic Stroke: A Multicenter Analysis Open
BACKGROUND Cerebral white matter disease (WMD) may result from the accumulation of silent embolic brain infarcts in the setting of subclinical, nonstenotic cervical carotid atherosclerosis. The contribution of cervical plaque to the burden…
View article: Validation of the Ultimate Stroke Scale (USS): A standardized tool for automated large vessel occlusion screening
Validation of the Ultimate Stroke Scale (USS): A standardized tool for automated large vessel occlusion screening Open
Background Prehospital stroke screening for large vessel occlusions (LVOs) varies across institutions. This study compares manual stroke scale calculations against e-calculated scores using the Ultimate Stroke Scale (USS), a software autom…
View article: Balloon guide catheter use for carotid body tumor embolization: A retrospective case series
Balloon guide catheter use for carotid body tumor embolization: A retrospective case series Open
Background Carotid body tumors (CBTs) are neuroendocrine tumors that arise from the carotid body. The malignant cases can present with a multitude of complications. Thus, surgical resection is the preferred treatment of choice. However, pr…
View article: Revisiting the Etiology of Cocaine-Related Ischemic Strokes: An Observational Cohort
Revisiting the Etiology of Cocaine-Related Ischemic Strokes: An Observational Cohort Open
View article: Flex vs. Vantage Pipeline™ Flow Diverters: Technical analysis in treating complex fusiform basilar artery aneurysm
Flex vs. Vantage Pipeline™ Flow Diverters: Technical analysis in treating complex fusiform basilar artery aneurysm Open
We present a case of an adult patient with a large symptomatic fusiform basilar artery aneurysm. This video demonstrates the ease of deploying the new Pipeline™ Vantage Flow Diverter compared to the Flex model in the same vessel. The Flex …
View article: Fourth-generation Pipeline<sup>™</sup> Vantage flow diversion: First reported US experience of safety and feasibility
Fourth-generation Pipeline<sup>™</sup> Vantage flow diversion: First reported US experience of safety and feasibility Open
Background The Pipeline ™ Vantage embolization device (Medtronic, Irvine, CA) is the fourth generation of Pipeline flow diverter devices, offering numerous technical improvements. This study aimed to assess the feasibility and safety of Th…
View article: Estimated benefit of PCSK9 inhibition following ischemic stroke due to severe intracranial atherosclerosis
Estimated benefit of PCSK9 inhibition following ischemic stroke due to severe intracranial atherosclerosis Open
Background The risk of recurrent atherosclerotic vascular events in patients with stroke due to intracranial atherosclerotic disease (ICAD) is high. Proprotein convertase subtilisin/kexin type 9 inhibitors (PCSK9i) can dramatically lower l…
View article: Use of Onyx Frontier<sup>™</sup> for intracranial stenting in stroke patients: A multicenter retrospective study
Use of Onyx Frontier<sup>™</sup> for intracranial stenting in stroke patients: A multicenter retrospective study Open
Background Acute ischemic stroke (AIS) due to intracranial atherosclerotic disease (ICAD) carries a high risk of recurrence despite aggressive medical management. The aim of our study is to present our initial experience with the Onyx Fron…
View article: Early single-center experience with middle meningeal artery embolization using Zoom<sup>™</sup> 45 Catheter
Early single-center experience with middle meningeal artery embolization using Zoom<sup>™</sup> 45 Catheter Open
Background Middle meningeal artery (MMA) embolization for subdural hematomas (SDH) and dural arteriovenous fistulas (dAVFs) has gained momentum in the neuroendovascular space. However, there is variability in the technique for safe and eff…
View article: Endovascular Thrombectomy with or without Bridging Thrombolysis in Acute Ischemic Stroke: A Cost-Effectiveness Analysis
Endovascular Thrombectomy with or without Bridging Thrombolysis in Acute Ischemic Stroke: A Cost-Effectiveness Analysis Open
Background: There is unclear added benefit of intravenous thrombolysis (IVT) with endovascular thrombectomy (EVT). We performed a cost-effectiveness analysis to assess the cost-effectiveness of comparing EVT with IVT versus E…
View article: Intravenous cangrelor use for neuroendovascular procedures: a two-center experience and updated systematic review
Intravenous cangrelor use for neuroendovascular procedures: a two-center experience and updated systematic review Open
Background The optimal antiplatelet therapy regimen for certain neuroendovascular procedures remains unclear. This study investigates the safety and feasibility of intravenous dose-adjusted cangrelor in patients undergoing acute neuroendov…
View article: Abstract 053: Reduced‐Dose Ticagrelor Versus Full‐Dose Ticagrelor Versus Clopidogrel In Acute Stroke Management: A Retrospective Cohort Study
Abstract 053: Reduced‐Dose Ticagrelor Versus Full‐Dose Ticagrelor Versus Clopidogrel In Acute Stroke Management: A Retrospective Cohort Study Open
Introduction Ticagrelor use has become more prominent in acute ischemic stroke management in the presence of clopidogrel resistance(1‐2). This study compares the effectiveness of aspirin plus ticagrelor at different doses versus clopidogre…
View article: Abstract 216: Endovascular Thrombectomy +/‐ Thrombolytics In Patients With Cocaine‐Related Acute Ischemic Stroke
Abstract 216: Endovascular Thrombectomy +/‐ Thrombolytics In Patients With Cocaine‐Related Acute Ischemic Stroke Open
Introduction The safety of thrombolytic therapy in patients with cocaine‐related acute ischemic strokes (AIS) has been investigated, but the safety of endovascular thrombectomy in cocaine‐related AIS remains unknown (1‐2). Here, we report …
View article: Abstract 263: Cocaine Use and Acute Ischemic Stroke: Determining TOAST Etiology & Infarct Locations
Abstract 263: Cocaine Use and Acute Ischemic Stroke: Determining TOAST Etiology & Infarct Locations Open
Introduction Cocaine‐induced vasospasm of small vessels has long been proposed as a mechanism for ischemic stroke (1). However, there are limited studies to date that have classified cocaine‐related ischemic strokes under a subtype of the …
View article: Endovascular Thrombectomy With or Without Thrombolysis for Stroke: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Endovascular Thrombectomy With or Without Thrombolysis for Stroke: A Systematic Review and Meta-Analysis of Randomized Controlled Trials Open
Background To this date, whether to administer intravenous thrombolysis (IVT) prior to endovascular thrombectomy (EVT) for stroke patients still stirs some debate. We aimed to systematically update the evidence from randomized trials compa…
View article: O28/275 Cost utility analysis of bridging intravenous thrombolysis with endovascular thrombectomy
O28/275 Cost utility analysis of bridging intravenous thrombolysis with endovascular thrombectomy Open
Introduction Clinical equipoise exists behind bridging intravenous thrombolysis (BT) with endovascular thrombectomy (EVT). Aim of Study To compare the cost-effectiveness of EVT alone vs. BT in acute ischemic stroke (AIS) Methods We conduct…
View article: P134/298 Endovascular therapy delay for acute large vessel occlusions is associated with worse functional outcome and increased mortality – Quantified
P134/298 Endovascular therapy delay for acute large vessel occlusions is associated with worse functional outcome and increased mortality – Quantified Open
Introduction Early mechanical thrombectomy (MT) improves functional outcomes for patients with acute LVO. It has been shown that earlier MT resulted in reduced hospital stay and improved living situation at 90 days after stroke. Aim of Stu…
View article: P176/321 Using the onyx resolute stent for large vessel occlusions and underlying intracranial atherosclerotic disease
P176/321 Using the onyx resolute stent for large vessel occlusions and underlying intracranial atherosclerotic disease Open
Introduction Large Vessel Occlusion LVO in the setting of underlying intracranial atherosclerosis disease ICAD is challenging with limited data to suggest best therapy Aim of Study To report a case of using Onyx Resolute stent in setting o…
View article: P171/283 The Zoom RDL radial access system for neurointervention: an early single-center experience
P171/283 The Zoom RDL radial access system for neurointervention: an early single-center experience Open
Introduction The transradial (TRA) approach for neurointerventional procedures is increasingly being used given its technical feasibility and safety. However, catheter trackability and device issues are reported barriers to TRA adoption. A…
View article: P170/281 Endovascular thrombectomy with or without thrombolysis bridging in patients with acute ischemic stroke: a systematic review and meta-analysis of randomized trials
P170/281 Endovascular thrombectomy with or without thrombolysis bridging in patients with acute ischemic stroke: a systematic review and meta-analysis of randomized trials Open
Introduction An updated analysis comparing endovascular thrombectomy (EVT) alone versus endovascular therapy without bridging intravenous thrombolysis (IVT) has not been performed. Aim of Study To systematically update the evidence from ra…
View article: P029/311 Brain stem AVM with intra-nidal AVM
P029/311 Brain stem AVM with intra-nidal AVM Open
Introduction Ruptured AVM with intra-nidal aneurysm still carry significant risk of treatment especially in the brain stem originating from basilar artery perforators Aim of Study To report a case of using liquid embolic and micro-coils in…
View article: P109/299 Imaging and mortality outcomes after middle meningeal artery embolization: a case-series report
P109/299 Imaging and mortality outcomes after middle meningeal artery embolization: a case-series report Open
Introduction SDHs are more prevalent among the elderly and can cause significant morbidity and mortality. n-BCA has proven to be an effective and safe agent for embolization of middle meningeal artery (MMA). Aim of Study We present a retro…
View article: P026/285 Endovascular thrombectomy for cerebral venous sinus thrombosis using the penumbra indigo aspiration system
P026/285 Endovascular thrombectomy for cerebral venous sinus thrombosis using the penumbra indigo aspiration system Open
Introduction We use the Penumbra Indigo® Aspiration System for the treatment of CVST in a timely manner for a 35-year-old male patient who presented with altered mental status with optimal outcomes on follow-up angiogram. Aim of Study We r…
View article: P168/276 Intravenous dose-adjusted cangrelor use for neuroendovascular procedures: an institutional experience
P168/276 Intravenous dose-adjusted cangrelor use for neuroendovascular procedures: an institutional experience Open
Introduction The safety and feasibility of intravenous cangrelor use for neuroendovascular procedures needs to be investigated. Aim of Study To investigate safety and feasibility of intravenous dose-adjusted cangrelor in patients undergoin…
View article: Endovascular thrombectomy with or without thrombolysis bridging in patients with acute ischaemic stroke: protocol for a systematic review, meta-analysis of randomised trials and cost-effectiveness analysis
Endovascular thrombectomy with or without thrombolysis bridging in patients with acute ischaemic stroke: protocol for a systematic review, meta-analysis of randomised trials and cost-effectiveness analysis Open
Introduction Current published guidelines and meta-analyses comparing endovascular thrombectomy (EVT) alone versus EVT with bridging intravenous thrombolysis (IVT) suggest that EVT alone is non-inferior to EVT with bridging thrombolysis in…
View article: Endovascular Thrombectomy for Large Ischemic Strokes: A Living Systematic Review and Meta-Analysis of Randomized Trials
Endovascular Thrombectomy for Large Ischemic Strokes: A Living Systematic Review and Meta-Analysis of Randomized Trials Open
Background and Purpose New studies have shown that endovascular thrombectomy (EVT) is safe and effective for acute ischemic stroke (AIS) patients with large ischemic areas. The aim of our study is to conduct a living systematic review and …
View article: The Zoom RDL radial access system for neurointervention: An early single-center experience
The Zoom RDL radial access system for neurointervention: An early single-center experience Open
Background The transradial approach (TRA) for neurointerventional procedures is increasingly being used given its technical feasibility and safety. However, catheter trackability and device deliverability are reported barriers to TRA adopt…
View article: Abstract Number ‐ 265: Reduced‐dose ticagrelor versus full‐dose ticagrelor in patients with stroke: A retrospective cohort study
Abstract Number ‐ 265: Reduced‐dose ticagrelor versus full‐dose ticagrelor in patients with stroke: A retrospective cohort study Open
Introduction There has been an increase in use of ticagrelor in patients with ischemic stroke, particularly in the setting of clopidogrel resistance. Our study aims to retrospectively determine if aspirin plus ticagrelor at a reduced dose …
View article: Abstract Number ‐ 176: Mechanical thrombectomy with or without bridging in stroke: A systematic review and meta‐analysis of RCTs
Abstract Number ‐ 176: Mechanical thrombectomy with or without bridging in stroke: A systematic review and meta‐analysis of RCTs Open
Introduction Current published guidelines and meta‐analyses comparing direct mechanical thrombectomy (MT) alone versus MT with bridging intravenous thrombolysis (IVT) suggested that MT alone is non‐inferior to MT with bridging thrombolysis…
View article: Abstract Number ‐ 93: Endovascular thrombectomy for cerebral venous sinus thrombosis using the Penumbra Indigo Aspiration System
Abstract Number ‐ 93: Endovascular thrombectomy for cerebral venous sinus thrombosis using the Penumbra Indigo Aspiration System Open
Introduction Cerebral venous sinus thrombosis (CVST) is an uncommon cause of stroke that can be difficult to treat. Endovascular thrombectomy techniques have evolved over time, but evidence behind the efficacy and safety of these technique…