Harshad Devarbhavi
YOU?
Author Swipe
View article: DNA Methylation change in genes involved in Alcohol metabolism (ALDH2) and One-carbon metabolism (MTHFR) pathways among people with Alcohol Use Disorder
DNA Methylation change in genes involved in Alcohol metabolism (ALDH2) and One-carbon metabolism (MTHFR) pathways among people with Alcohol Use Disorder Open
Background: Alcohol Use Disorder (AUD) is a significant public health issue influenced by genetic and environmental factors. Genetic loci linked to age of initiation, response to alcohol, and withdrawal complications.Alcohol inhibits methi…
View article: Natural History of Idiosyncratic Drug‐Induced Liver Injury and Prognostic Models
Natural History of Idiosyncratic Drug‐Induced Liver Injury and Prognostic Models Open
Background and Aims: Drug‐induced liver injury (DILI) remains a leading cause of acute liver failure worldwide. Drugs such as isoniazid, alone or in combination with other anti‐tuberculosis drugs, as well as a growing number of herbal and …
View article: Synchronous Hepatic Artery and Portal Vein Thrombosis in COVID-19 infection- A case report
Synchronous Hepatic Artery and Portal Vein Thrombosis in COVID-19 infection- A case report Open
Background: COVID-19, which primarily affects the respiratory system, can also lead to systemic complications, including thrombotic events. Althoughthromboses in the hepatic and portal systems are rare, they mayresult in serious complicati…
View article: Acute-on-chronic liver failure (ACLF): the ‘Kyoto Consensus’—steps from Asia
Acute-on-chronic liver failure (ACLF): the ‘Kyoto Consensus’—steps from Asia Open
View article: Ammonia is associated with liver-related complications and predicts mortality in acute-on-chronic liver failure patients
Ammonia is associated with liver-related complications and predicts mortality in acute-on-chronic liver failure patients Open
The relationship between ammonia and liver-related complications (LRCs) in acute-on-chronic liver failure (ACLF) patients is not clearly established. This study aimed to evaluate the association between ammonia levels and LRCs in patients …
View article: Drug-induced liver injury in patients with underlying liver disease
Drug-induced liver injury in patients with underlying liver disease Open
View article: Clinical Features, Laboratory Characteristics and Outcome from Oral Contraceptives-induced Liver Injury in 43 Consecutive Patients and a Brief Review of Published Reports
Clinical Features, Laboratory Characteristics and Outcome from Oral Contraceptives-induced Liver Injury in 43 Consecutive Patients and a Brief Review of Published Reports Open
View article: Ammonia is associated with liver-related complications and predicts mortality in acute-on-chronic liver failure patients.
Ammonia is associated with liver-related complications and predicts mortality in acute-on-chronic liver failure patients. Open
Background and aims: The relationship between ammonia and liver-related complications (LRCs) in acute-on-chronic liver failure (ACLF) patients is not well defined. This study aimed to evaluate the association of ammonia levels with LRCs in…
View article: Endoscopic Management of Pediatric Foreign Body Ingestions and Food Bolus Impactions: A Retrospective Study from a Tertiary Care Center
Endoscopic Management of Pediatric Foreign Body Ingestions and Food Bolus Impactions: A Retrospective Study from a Tertiary Care Center Open
Background Foreign body (FB) ingestion is a common pediatric problem with the majority of these occurring in children younger than 3 years. Management varies depending on the age of the patient, ingested object(s), its location along the d…
View article: Nomenclature, diagnosis and management of drug-induced autoimmune-like hepatitis (DI-ALH): An expert opinion meeting report
Nomenclature, diagnosis and management of drug-induced autoimmune-like hepatitis (DI-ALH): An expert opinion meeting report Open
View article: Global burden of liver disease: 2023 update
Global burden of liver disease: 2023 update Open
Liver disease accounts for two million deaths annually and is responsible for 4% of all deaths (1 out of every 25 deaths worldwide); approximately two-thirds of all liver-related deaths occur in men. Deaths are largely attributable to comp…
View article: Portosystemic Shunt Presenting as Spastic Paraparesis in a Patient with Non-Cirrhotic Portal Hypertension
Portosystemic Shunt Presenting as Spastic Paraparesis in a Patient with Non-Cirrhotic Portal Hypertension Open
View article: Severe Neutropenia Associated With Hypersplenism and Portal Hypertension: Does it Predispose to Increased Infection Episodes?
Severe Neutropenia Associated With Hypersplenism and Portal Hypertension: Does it Predispose to Increased Infection Episodes? Open
View article: Tale(S) of twisted stomach: A case series of five patients
Tale(S) of twisted stomach: A case series of five patients Open
Gastric volvulus (GV) is a clinical condition that occurs due to abnormal rotation of the stomach around its mesentery by at least 180° and can present as either acute, recurrent, intermittent, or chronic foregut obstruction. While acute G…
View article: Predictive Scores for Mortality in MAFLD-Related Acute-on-Chronic Liver Failure (MAFLD-ACLF): Development and Validation of MAFLD-MELD-Na and MAFLD-AARC Scores.
Predictive Scores for Mortality in MAFLD-Related Acute-on-Chronic Liver Failure (MAFLD-ACLF): Development and Validation of MAFLD-MELD-Na and MAFLD-AARC Scores. Open
View article: Endoscopic Cyanoacrylate Glue Injection for Duodenal Varices—A Single-Center Study
Endoscopic Cyanoacrylate Glue Injection for Duodenal Varices—A Single-Center Study Open
Aim/Objectives Duodenal varices (DVs), although rare, can present with massive, potentially fatal upper gastrointestinal bleeding; however, there are no randomized trials regarding management of this relatively uncommon presentation. We ai…
View article: Hypertriglyceridemia-Induced Acute Pancreatitis – Course, Outcome, and Comparison with Non-Hypertriglyceridemia Associated Pancreatitis
Hypertriglyceridemia-Induced Acute Pancreatitis – Course, Outcome, and Comparison with Non-Hypertriglyceridemia Associated Pancreatitis Open
Background: Although hypertriglyceridemia (HTG) is a well-established cause of acute pancreatitis (AP), there are no definitive management guidelines. Studies comparing clinical severity and outcome of hypertriglyceridemia-induced acute pa…
View article: Response to Tinospora cordifolia (giloy)‐induced liver injury during the COVID‐19 pandemic—Multicenter nationwide study from India
Response to Tinospora cordifolia (giloy)‐induced liver injury during the COVID‐19 pandemic—Multicenter nationwide study from India Open
I read with interest the article Tinospora cordifolia (Giloy)-Induced Liver Injury During the COVID-19 Pandemic—Multicenter Nationwide Study From India, by Kulkarni and colleagues.[1] The study builds on the evidence that T. cordifolia cau…
View article: Abstract 68: Hypertriglyceridemia-induced acute pancreatitis – Experience from a single center of 20 patients
Abstract 68: Hypertriglyceridemia-induced acute pancreatitis – Experience from a single center of 20 patients Open
Background and Aim: Although hypertriglyceridemia (HTG) is a well-established cause of acute pancreatitis (AP), there are no clear-cut therapeutic guidelines. Furthermore, studies regarding treatment and outcome of hypertriglyceridemia-ind…
View article: <scp>Leflunomide‐induced</scp> liver injury: Differences in characteristics and outcomes in Indian and <scp>US</scp> registries
<span>Leflunomide‐induced</span> liver injury: Differences in characteristics and outcomes in Indian and <span>US</span> registries Open
Background Leflunomide, a disease‐modifying anti‐rheumatic drug, has been associated with elevations of serum aminotransferases. Herein, we describe the clinical, laboratory features and outcomes of 17 patients with leflunomide/teriflunomi…
View article: Erratum to ‘Indian National Association for the Study of Liver Consensus Statement on Acute Liver Failure (Part-2): Management of Acute Liver Failure’ [J Clin Exp Hepatol 10 (2020) 477-517]
Erratum to ‘Indian National Association for the Study of Liver Consensus Statement on Acute Liver Failure (Part-2): Management of Acute Liver Failure’ [J Clin Exp Hepatol 10 (2020) 477-517] Open
View article: Impact of Covid -19 epidemic on hospital admissions for alcohol related liver diseases and pancreatitis: A single centre experience
Impact of Covid -19 epidemic on hospital admissions for alcohol related liver diseases and pancreatitis: A single centre experience Open
View article: Alcohol Liver Cirrhosis May Have a Higher Genetic Risk Score
Alcohol Liver Cirrhosis May Have a Higher Genetic Risk Score Open
SNP-based genetic risk score prediction can be used to predict the risk of developing cirrhosis in alcohol use disorder individuals. We used SNP-GRS for risk assessment at the individual level. The study included men with AUD-Cve N131 and …
View article: Impact of compensated cirrhosis on survival in patients with acute-on-chronic liver failure
Impact of compensated cirrhosis on survival in patients with acute-on-chronic liver failure Open
View article: Primary Intestinal Lymphoma: Clinicopathological Characteristics of 55 Patients
Primary Intestinal Lymphoma: Clinicopathological Characteristics of 55 Patients Open
Malipatel R, Patil M, Rout P, et al. Primary Intestinal Lymphoma: Clinicopathological Characteristics of 55 Patients. Euroasian J Hepato-Gastroenterol 2021;11(2):71-75.
View article: Drug‐Induced Liver Injury Unique to India
Drug‐Induced Liver Injury Unique to India Open
Content available: Audio Recording The drugs causing drug-induced liver injury (DILI) tend to vary geographically based on specific disease states. In India, it is compounded by the ubiquitous use of traditional and complementary medicines…
View article: Association of human leukocyte antigen‐B*13:01 with dapsone‐induced liver injury
Association of human leukocyte antigen‐B*13:01 with dapsone‐induced liver injury Open
Human leukocyte antigens (HLA) have been linked to adverse drug reactions. Generally, HLA association is phenotype specific and is related to either liver or skin injury. HLA‐A*13:01 has been linked to dapsone‐induced severe cutaneous drug…
View article: Lessons of the month 1: Cardiac tamponade: don't forget the pancreas
Lessons of the month 1: Cardiac tamponade: don't forget the pancreas Open
View article: Genetics and Epigenetics of Aldehyde Dehydrogenase (ALDH2) in Alcohol Related Liver Disease
Genetics and Epigenetics of Aldehyde Dehydrogenase (ALDH2) in Alcohol Related Liver Disease Open
Alcohol dependence and cirrhosis are key outcomes of excessive alcohol use. We studied the interaction between genetics and epigenetics at the aldehyde dehydrogenase ( ALDH2 ) locus to understand differences in vulnerability to cirrhosis. …
View article: Pancreatic Arteriovenous Malformation: A Case Report and Review of Literature
Pancreatic Arteriovenous Malformation: A Case Report and Review of Literature Open