Harshal A. Shah
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View article: NCOG-58. Connectomics-based Quantitative Tractometry in Brain Tumor Surgery: AI-Guided Network Analysis for Optimizing Onco-Functional Balance
NCOG-58. Connectomics-based Quantitative Tractometry in Brain Tumor Surgery: AI-Guided Network Analysis for Optimizing Onco-Functional Balance Open
Contemporary brain tumor surgery increasingly prioritizes a network-based view of cerebral function, shifting from localizationist models toward a meta-network framework that recognizes the brain as an interconnected system. We hypothesize…
View article: IMG-101. Connectomic-Guided Minimally Invasive Tumor Resection Using Tubular Retractors: A Quantitative Tractometry Analysis with AI-Based Software
IMG-101. Connectomic-Guided Minimally Invasive Tumor Resection Using Tubular Retractors: A Quantitative Tractometry Analysis with AI-Based Software Open
Deep-seated tumors present a significant surgical challenge due to the risk of damaging critical brain networks. Minimally invasive approaches using tubular retractors aim to reduce collateral damage by displacing rather than transecting t…
View article: IMG-73. Functional connectivity alterations in disorders of consciousness: a systematic review and exploratory coordinate-based meta-analysis
IMG-73. Functional connectivity alterations in disorders of consciousness: a systematic review and exploratory coordinate-based meta-analysis Open
PURPOSE Disorders of consciousness (DoC), including coma, unresponsive wakefulness syndrome (UWS), and minimally conscious state (MCS), present significant diagnostic and prognostic challenges due to limited behavioral responsiveness and c…
View article: RADT-08. INCIDENCE AND RISK OF SYMPTOMATIC RADIATION NECROSIS FOLLOWING INTRACRANIAL BRACHYTHERAPY: A SYSTEMATIC REVIEW AND META-ANALYSIS
RADT-08. INCIDENCE AND RISK OF SYMPTOMATIC RADIATION NECROSIS FOLLOWING INTRACRANIAL BRACHYTHERAPY: A SYSTEMATIC REVIEW AND META-ANALYSIS Open
PURPOSE Brachytherapy, offering highly localized radiation delivery while minimizing exposure to surrounding tissues, has reemerged as a promising treatment modality for primary and secondary brain tumors. Despite its usefulness, a signifi…
View article: Mechanistic insights and basis for real-time monitoring and closed-loop feedback control in sonodynamic therapy for glioblastoma
Mechanistic insights and basis for real-time monitoring and closed-loop feedback control in sonodynamic therapy for glioblastoma Open
Sonodynamic therapy (SDT) involves the administration of otherwise inactive agents that can be activated by acoustic energy ('sonosensitizers') to impart therapeutic effects. SDT is a treatment of significant clinical interest in glioblast…
View article: Microsurgical clipping of a recurrent anterior communicating artery aneurysm following WEB intrasaccular embolization: illustrative case
Microsurgical clipping of a recurrent anterior communicating artery aneurysm following WEB intrasaccular embolization: illustrative case Open
BACKGROUND The Woven EndoBridge (WEB) embolization system is an endovascularly deployed intrasaccular device that promotes occlusion in cerebrovascular aneurysms through intra-aneurysmal thrombosis. While the safety and efficacy of the WEB…
View article: Precision Oncology in Non-small Cell Lung Cancer: A Comparative Study of Contextualized ChatGPT Models
Precision Oncology in Non-small Cell Lung Cancer: A Comparative Study of Contextualized ChatGPT Models Open
The performance gains observed following contextualization suggest that broader applications of LLMs in oncology may exist than current literature indicates. This study provides proof of concept for the use of contextualized GPT models in …
View article: Intramedullary primary spinal cord melanoma: illustrative case
Intramedullary primary spinal cord melanoma: illustrative case Open
BACKGROUND Intramedullary primary spinal melanoma (IPSM) is a rare tumor, with limited reports on its clinical presentation, radiographic features, histopathological and genetic factors, diagnosis, and management. OBSERVATIONS A 49-year-ol…
View article: Implementation of a Digital Health Technology Platform Improves Neurosurgical Resident Communication Skills
Implementation of a Digital Health Technology Platform Improves Neurosurgical Resident Communication Skills Open
The implementation of a platform that generates customized audiovisual content during routine patient-provider interactions may be a valuable tool for resident education, particularly regarding interpersonal skills and understanding of pat…
View article: Why are clinical trials of deep brain stimulation terminated? An analysis of clinicaltrials.gov
Why are clinical trials of deep brain stimulation terminated? An analysis of clinicaltrials.gov Open
One in five clinical trials for DBS were found to be unsuccessful, most commonly due to patient recruitment difficulties. The source of funding was the only factor associated with trial success. As DBS research continues to grow, understan…
View article: RADT-49. A SYSTEMATIC REVIEW AND META-ANALYSIS OF HIPPOCAMPAL AVOIDANCE IN WHOLE BRAIN RADIOTHERAPY AND PROPHYLACTIC CRANIAL IRRADIATION
RADT-49. A SYSTEMATIC REVIEW AND META-ANALYSIS OF HIPPOCAMPAL AVOIDANCE IN WHOLE BRAIN RADIOTHERAPY AND PROPHYLACTIC CRANIAL IRRADIATION Open
PURPOSE: Hippocampal-avoidance radiotherapy has been under investigation as a technique to improve neurocognitive function in patients undergoing whole brain radiotherapy (WBRT) for intracerebral tumor treatment and control. To understand …
View article: RADT-03. A CASE OF PARTIAL HIPPOCAMPAL-AVOIDANCE WHOLE BRAIN RADIOTHERAPY IN A PATIENT WITH METASTATIC INFILTRATION OF THE LEFT HIPPOCAMPUS
RADT-03. A CASE OF PARTIAL HIPPOCAMPAL-AVOIDANCE WHOLE BRAIN RADIOTHERAPY IN A PATIENT WITH METASTATIC INFILTRATION OF THE LEFT HIPPOCAMPUS Open
In addition to surgical resection and systemic therapy, whole brain radiotherapy (WBRT) is a crucial modality in the treatment of cancers that have metastasized to the brain. It has been shown to improve intracranial disease control and ov…
View article: QLTI-06. CHARACTERISTICS OF TERMINATED GLIOBLASTOMA-RELATED CLINICAL TRIALS: A REVIEW OF THE CLINICALTRIALS.GOV DATABASE
QLTI-06. CHARACTERISTICS OF TERMINATED GLIOBLASTOMA-RELATED CLINICAL TRIALS: A REVIEW OF THE CLINICALTRIALS.GOV DATABASE Open
Glioblastoma multiforme (GBM) is a devastating primary central nervous system tumor. Although past clinical trials have incrementally improved prognosis overall survival remains poor, emphasizing a need for further successful clinical tria…
View article: Local Field Potentials in Deep Brain Stimulation: Investigation of the Most Cited Articles
Local Field Potentials in Deep Brain Stimulation: Investigation of the Most Cited Articles Open
The implementation of DBS LFPs is a novel field that is rapidly growing. However, a need exists for more studies with larger patient cohorts and more randomized controlled trials to further elucidate the benefits of this technology. These …
View article: #Neurosurgery: A Cross-Sectional Analysis of Neurosurgical Content on TikTok
#Neurosurgery: A Cross-Sectional Analysis of Neurosurgical Content on TikTok Open
Neurosurgical content on TikTok contains a high degree of bias across all creator and video types. Entertaining videos are associated with the highest numbers of likes but also the greatest bias. These data may be used to guide institution…
View article: Analysis of factors leading to early termination in glioblastoma-related clinical trials
Analysis of factors leading to early termination in glioblastoma-related clinical trials Open