Haruka Kudo
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View article: Specific Cardiovascular Mortality in Cancer Survivors: A Nationwide Population‐Based Cohort Study in Japan
Specific Cardiovascular Mortality in Cancer Survivors: A Nationwide Population‐Based Cohort Study in Japan Open
Background Improvements in cancer survivorship have led to concern about cardiovascular disease (CVD) among cancer survivors. This study aimed to investigate CVD mortality in patients with cancer compared with the general population, with …
View article: Non-cancer-related Deaths in Cancer Survivors: A Nationwide Population-based Study in Japan
Non-cancer-related Deaths in Cancer Survivors: A Nationwide Population-based Study in Japan Open
The proportion of non-cancer-related deaths among cancer patients has increased over time, emphasizing the need to manage cancer and its comorbidities carefully.
View article: Prognostic impact of coexisting cardiovascular disease in patients with cancer: A multicenter retrospective cohort study
Prognostic impact of coexisting cardiovascular disease in patients with cancer: A multicenter retrospective cohort study Open
Coexisting CVD and HF severity at cancer diagnosis is associated with survival in patients with cancer.
View article: Prognostic impact of the presence or absence of prior cancer in patients with cancer using cure models: A population‐based study
Prognostic impact of the presence or absence of prior cancer in patients with cancer using cure models: A population‐based study Open
Developing a subsequent cancer is one of the major concerns for cancer survivors; however, whether prior cancer could affect their prognosis is unknown. We therefore aimed to analyze how prognosis varies depending on prior cancer in patien…
View article: Age-Dependent Causes of Death among Patients with Breast Cancer Based on Osaka Cancer Registry and Vital Statistics in Japan
Age-Dependent Causes of Death among Patients with Breast Cancer Based on Osaka Cancer Registry and Vital Statistics in Japan Open
We aimed to clarify the differences in causes of death among patients with breast cancer according to age at diagnosis and years elapsed since diagnosis. Using data from the Osaka Cancer Registry and Vital Statistics databases, 40,690 fema…
View article: Cause of Death among Long-Term Cancer Survivors: The NANDE Study
Cause of Death among Long-Term Cancer Survivors: The NANDE Study Open
Survival information for Japanese patients with cancer is based only on survival status and the cause of death among these patients remains unclear. In this study, Osaka Cancer Registry data (1985–2014) and vital statistics data (1985–2016…
View article: Patterns of staging, treatment, and mortality in gastric, colorectal, and lung cancer among older adults with and without preexisting dementia: a Japanese multicentre cohort study
Patterns of staging, treatment, and mortality in gastric, colorectal, and lung cancer among older adults with and without preexisting dementia: a Japanese multicentre cohort study Open
Background Little is known about dementia’s impact on patterns of diagnosis, treatment, and outcomes in cancer patients. This study aimed to elucidate the differences in cancer staging, treatment, and mortality in older cancer patients wit…
View article: The Effect of High Molecular Weight Hyaluronic Acid and Latanoprost Eyedrops on Tear Functions and Ocular Surface Status in C57/BL6 Mice
The Effect of High Molecular Weight Hyaluronic Acid and Latanoprost Eyedrops on Tear Functions and Ocular Surface Status in C57/BL6 Mice Open
Anti-glaucoma eye drop treatment often induces ocular surface problems, including dry eyes, and may be associated with poor medication compliance. This study aimed to investigate the effects of a novel high molecular weight hyaluronic acid…
View article: Impact of coexisting diabetes on survival and risk of developing second primary cancer in diabetes patients receiving drug therapy: A multicenter retrospective cohort study of patients with cancer in Japan
Impact of coexisting diabetes on survival and risk of developing second primary cancer in diabetes patients receiving drug therapy: A multicenter retrospective cohort study of patients with cancer in Japan Open
Aims/Introduction We investigated the association between coexisting diabetes at the time of cancer diagnosis, and the overall survival and incidence of second primary cancer in patients with cancer and receiving drug therapy for diabetes.…
View article: Incidence and relative risk of metachronous second primary cancers for 16 cancer sites, Osaka, Japan, 2000–2015: Population‐based analysis
Incidence and relative risk of metachronous second primary cancers for 16 cancer sites, Osaka, Japan, 2000–2015: Population‐based analysis Open
Background An increasing number of cancer survivors have developed multiple primaries. This study aims to describe the incidence and risk patterns of metachronous second primary cancers (SPCs) in Osaka, Japan. Methods Data were obtained fr…
View article: The Effects of High Molecular Weight Hyaluronic Acid Eye Drop Application in Environmental Dry Eye Stress Model Mice
The Effects of High Molecular Weight Hyaluronic Acid Eye Drop Application in Environmental Dry Eye Stress Model Mice Open
Hyaluronic acid (HA) ophthalmic solution is widely used in dry eye treatment worldwide. However, there are no reports comparing the dry eye treatment effects of high molecular weight HA with low molecular weight HA. Sixty eight-week-old C5…
View article: Feasibility of Strip Meniscometry for Tear Volume Evaluation in Lacrimal Passage Obstruction
Feasibility of Strip Meniscometry for Tear Volume Evaluation in Lacrimal Passage Obstruction Open
Strip meniscometry tube (SMTube) is useful for assessing tear volume in dry eye disease. We performed an in vitro and a clinical study to examine whether the SMTube can also be used to evaluate tear quantity in lacrimal passage obstruction…
View article: Identification of <i>Venturia inaequalis</i> Races in Morioka, Japan and Identification of a Quantitative Trait Locus Associated with Resistance to Apple Scab in ‘Akane’ Apples
Identification of <i>Venturia inaequalis</i> Races in Morioka, Japan and Identification of a Quantitative Trait Locus Associated with Resistance to Apple Scab in ‘Akane’ Apples Open
Apple scab, which is caused by Venturia inaequalis (Cooke) G. Wint., is a destructive disease that affects apples (Malus × domestica Borkh.). To develop an approach to breeding apples for scab resistance, race distribution of V. inaequalis…
View article: Effect of leucine and valine supplementation on liver lipid accumulation and proinflammation in diet-induced obese mice
Effect of leucine and valine supplementation on liver lipid accumulation and proinflammation in diet-induced obese mice Open
近年，肥満の増加に伴い，併発する頻度の高い非アルコール性脂肪肝(NAFLD)が着目されている．日本でのNAFLD有病率は約30%と報告されており，今後さらに増加していくと予測されている．分岐鎖アミノ酸(BCAA)は以前より骨格筋合成促進作用があるとされサプリメント等で使用されてきたが，近年脂肪蓄積抑制作用があると報告されている．そこで，食餌性肥満モデルマウスにおけるBCAAの肝臓脂質蓄積への影響について検討を行った．飼料はAIN-93G組成を基本とし，20%カゼインをコント…
View article: Effects of liquid konjac on parameters related to obesity in diet-induced obese mice
Effects of liquid konjac on parameters related to obesity in diet-induced obese mice Open
Konjac-mannan has been suggested to exert a protective effect against visceral obesity. However, there is little knowledge about the effects of liquid konjac (LK) that is partially alkali gelled. The purpose of the present work was to eval…
View article: Effects of Softened <i>Kombu</i> Supplementation on Parameters Related to Metabolic Syndrome in Mice with Diet-induced Obesity
Effects of Softened <i>Kombu</i> Supplementation on Parameters Related to Metabolic Syndrome in Mice with Diet-induced Obesity Open
軟化処理昆布の摂取が食餌性肥満モデルマウスのメタボリックシンドローム関連指標に及ぼす影響について検討した。C57BL/6Jの雄性マウスを3群に分け, 高脂肪食に総食物繊維量が5%になるようにセルロース (CO群) , 乾燥昆布 (IN群) , 軟化処理昆布 (SO群) を添加した飼料を用いて12週間飼育した。その結果, 肝臓脂質量, 血清インスリンやレプチン濃度は, CO群に比べて試験群は有意に低下した。一方, 腹腔内脂肪重量, 脂肪細胞サイズ, 血清コレステロール濃度はS…
View article: Study of inhibitory effect of food components on the chronic inflammation in obesity model mice
Study of inhibitory effect of food components on the chronic inflammation in obesity model mice Open
β-グルカンに富む大麦，乳酸桿菌（Lactobacillus plantarum），および乳清たんぱく質を高脂肪食に配合してC57BL/6Jマウスに給餌して，組織中の炎症マーカーの遺伝子発現を調べた．