Anwarul Hassan Gilani
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View article: Antispasmodic Activity of Dried Ginger 70% MethanolicCrude Extract in Isolated Smooth Muscle Preparations
Antispasmodic Activity of Dried Ginger 70% MethanolicCrude Extract in Isolated Smooth Muscle Preparations Open
View article: An insight investigation to the antiurolithic activity of Trachyspermum ammi using the in vitro and in vivo experiments
An insight investigation to the antiurolithic activity of Trachyspermum ammi using the in vitro and in vivo experiments Open
The crude extract of Trachyspermum ammi seeds (Ta.Cr) was studied for its antiurolithic activity using the in vivo and in vitro experiments. In the in vivo experiments, Ta.Cr treatment showed a diuretic activity at the dose of 30 and 100 m…
View article: Sarcorucinine-D Inhibits Cholinesterases and Calcium Channels: Molecular Dynamics Simulation and In Vitro Mechanistic Investigations
Sarcorucinine-D Inhibits Cholinesterases and Calcium Channels: Molecular Dynamics Simulation and In Vitro Mechanistic Investigations Open
Acetylcholinesterase (AChE) inhibitors and calcium channel blockers are considered effective therapies for Alzheimer’s disease. AChE plays an essential role in the nervous system by catalyzing the hydrolysis of the neurotransmitter acetylc…
View article: Trigonella foenum‐graecum Methanolic Extract on Isolated Smooth Muscles and Acetylcholinesterase Enzyme: An In Vitro and Mechanistic In Silico Investigation
Trigonella foenum‐graecum Methanolic Extract on Isolated Smooth Muscles and Acetylcholinesterase Enzyme: An In Vitro and Mechanistic In Silico Investigation Open
Background and Objective . Trigonella foenum‐graecum Linn., also called fenugreek, is a popular medicinal plant cultivated all over the globe. Fenugreek seeds are known for their many medicinal properties. We present our findings on the ef…
View article: Species-Specific Spasmolytic Effect Of Aspalathus Linearis Aqueous Crude Extract
Species-Specific Spasmolytic Effect Of Aspalathus Linearis Aqueous Crude Extract Open
View article: Systematic Review of Polyherbal Combinations Used in Metabolic Syndrome
Systematic Review of Polyherbal Combinations Used in Metabolic Syndrome Open
Background: Metabolic syndrome (MetS) is a multifactorial disease, whose main stay of prevention and management is life-style modification which is difficult to attain. Combination of herbs have proven more efficacious in multi-targeted di…
View article: Cardiac Depressant and Vasodialatory Effect of Flaxseed - Basis for the Medicinal use in Hypertension
Cardiac Depressant and Vasodialatory Effect of Flaxseed - Basis for the Medicinal use in Hypertension Open
Linum usitatissimum (Flaxseed) is known to be traditionally used for managing hypertension. In this study, we aim to provide a mechanistic basis for the medicinal use of Flaxseed in hypertension. The high-performance liquid chromatography …
View article: Spasmolytic Effect of Grewia asiatica Fruit Extract on Isolated Smooth Muscles is Mediated via Multiple Pathways
Spasmolytic Effect of Grewia asiatica Fruit Extract on Isolated Smooth Muscles is Mediated via Multiple Pathways Open
Background. Grewia asiatica Linn, or phalsa, is a commonly consumed fruit in Pakistan. The fruit is employed in the traditional medicine practice of Pakistan as a smooth muscle relaxant in different gastrointestinal (GI) and cardiovascular…
View article: Gastrouterine Smooth Muscle Tone Modulatory Action Of Neem Fruit Extract Is Mediated Via Muscarinic Receptors And Ca2+ Channels
Gastrouterine Smooth Muscle Tone Modulatory Action Of Neem Fruit Extract Is Mediated Via Muscarinic Receptors And Ca2+ Channels Open
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Aims and Scope: Phytotherapy Research is a monthly, international journal for the publication of original research papers, short communications, reviews and letters on medicinal plant research.Key areas of interest are pharmacology, toxico…
View article: Almond protects the liver in coronary artery disease – a randomized controlled clinical trial
Almond protects the liver in coronary artery disease – a randomized controlled clinical trial Open
Objective: To compare the effect of Pakistani and American almonds on serum concentration of liver enzymes in coronary artery disease patients.
Methods: The randomised controlled trial was conducted at the Cardiology Clinics of Aga Khan U…
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Aims and Scope: Phytotherapy Research is a monthly, international journal for the publication of original research papers, short communications, reviews and letters on medicinal plant research.Key areas of interest are pharmacology, toxico…
View article: Pharmacodynamic evaluation of Terminalia bellerica for its antihypertensive effect
Pharmacodynamic evaluation of Terminalia bellerica for its antihypertensive effect Open
Terminalia bellerica has been used as a folk medicine in a variety of ailments including hypertension. Our aim was to investigate the possible mechanism of its blood pressure (BP)-lowering effect. The crude extract of Terminalia bellerica …
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Aims and Scope: Phytotherapy Research is a monthly, international journal for the publication of original research papers, short communications, reviews and letters on medicinal plant research.Key areas of interest are pharmacology, toxico…
View article: Issue Information
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Aims and Scope: Phytotherapy Research is a monthly, international journal for the publication of original research papers, short communications, reviews and letters on medicinal plant research.Key areas of interest are pharmacology, toxico…
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No abstract is available for this article.
View article: The use of Euphorbia hirta L. (Euphorbiaceae) in diarrhea and constipation involves calcium antagonism and cholinergic mechanisms
The use of Euphorbia hirta L. (Euphorbiaceae) in diarrhea and constipation involves calcium antagonism and cholinergic mechanisms Open
View article: Multiple Mechanisms of Flaxseed: Effectiveness in Inflammatory Bowel Disease
Multiple Mechanisms of Flaxseed: Effectiveness in Inflammatory Bowel Disease Open
Ethnopharmacological Relevance . Natural products, like Flaxseed ( Linum usitatissimum ), have traditionally been used in inflammatory bowel disease (IBD). It is known to contain multiple constituents which may account for its effectivenes…
View article: Pharmacological studies on the laxative effects of Fagonia indica on rodents
Pharmacological studies on the laxative effects of Fagonia indica on rodents Open
This study explores the pharmacological basis for the folk use of Fagonia indica in constipation using in vivo and in vitro assays. The crude extract of F. indica contained tannins, saponins, anthraquinones, alkaloids, flavonoids, glycosid…
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View article: Cardioprotective Effects of Sphingosine-1-Phosphate Receptor Immunomodulator FTY720 in a Clinically Relevant Model of Cardioplegic Arrest and Cardiopulmonary Bypass
Cardioprotective Effects of Sphingosine-1-Phosphate Receptor Immunomodulator FTY720 in a Clinically Relevant Model of Cardioplegic Arrest and Cardiopulmonary Bypass Open
Objective: FTY720, an immunomodulator derived from sphingosine-1-phosphate, has recently demonstrated its immunomodulatory, anti-inflammatory, anti-oxidant, anti-apoptotic and anti-inflammatory properties. Furthermore, FTY720 might …
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View article: The Airway Relaxant Effect of Horse Purslane, Trianthema portulacastrum, Linn. (Aizoaceae), is Mediated through Dual Blockade of Muscarinic Receptors and Ca2+ Influx
The Airway Relaxant Effect of Horse Purslane, Trianthema portulacastrum, Linn. (Aizoaceae), is Mediated through Dual Blockade of Muscarinic Receptors and Ca2+ Influx Open
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View article: Vasodilator effect of 1-trifluoromethoxyphenyl-3-(1- propionylpiperidin-4-yl) urea is predominantly mediated through activation of voltage-dependent K+ channels
Vasodilator effect of 1-trifluoromethoxyphenyl-3-(1- propionylpiperidin-4-yl) urea is predominantly mediated through activation of voltage-dependent K+ channels Open
Purpose: To determine the mechanism of vasorelaxant effect of 1-trifluoromethoxyphenyl – 3 -(1-propionylpiperidin–4-yl) urea (TPPU) in cardiovascular diseases, including hypertension.Methods: Isolated rat thoracic aortic tissue preparation…
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No abstract is available for this article.
View article: Pharmacological basis for the medicinal use of polyherbal formulation and its ingredients in cardiovascular disorders using rodents
Pharmacological basis for the medicinal use of polyherbal formulation and its ingredients in cardiovascular disorders using rodents Open
These data show that POL4 and its constituents possess blood pressure lowering activity mediated through inhibition of Ca++ influx via membranous Ca++ channels and receptor (α-adrenergic) operated pathways.…