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View article: Susceptibility profile of <i>Aeromonas</i> spp. from clinical strains isolated in French Guiana
Susceptibility profile of <i>Aeromonas</i> spp. from clinical strains isolated in French Guiana Open
Aeromonas spp. are gram-negative bacilli of the Gammaproteobacteria class and Aeromonadaceae family. These bacteria are a public health challenge, particularly in South America. They harbor chromosomal β-lactamases belonging to classes B, …
View article: ADAMTS13 in Bothrops lanceolatus snakebite envenoming: Crude venom-induced reduction of in vitro enzymatic activity and clinical correlation in snakebite patients
ADAMTS13 in Bothrops lanceolatus snakebite envenoming: Crude venom-induced reduction of in vitro enzymatic activity and clinical correlation in snakebite patients Open
Background Envenoming by Bothrops lanceolatus , a viperid endemic to Martinique an island in the Lesser Antilles, induces a unique clinical manifestation, i.e., thrombosis. Pathophysiological signaling leading to thrombotic events remains …
View article: Pro-Angiogenic and Wound-Healing Potential of Bioactive Polysaccharides Extracted from Moroccan Algae Osmundea pinnatifida
Pro-Angiogenic and Wound-Healing Potential of Bioactive Polysaccharides Extracted from Moroccan Algae Osmundea pinnatifida Open
Various therapeutic approaches have been explored to speed up wound healing, with angiogenesis being a crucial factor in this process and skin repair. This study shows that a polysaccharide extracted from the red alga Osmundea pinnatifida …
View article: Early biomarkers of occupational strain in caregivers: The role of inflammatory, hematological, and oxidative stress markers in diagnosis
Early biomarkers of occupational strain in caregivers: The role of inflammatory, hematological, and oxidative stress markers in diagnosis Open
View article: Vascular leakage during circulatory failure: physiopathology, impact and treatments
Vascular leakage during circulatory failure: physiopathology, impact and treatments Open
View article: Cystoseira spinosa Polysaccharide: A Promising Natural Source for Antioxidant, Pro-Angiogenic, and Wound Healing Applications: In Silico Study
Cystoseira spinosa Polysaccharide: A Promising Natural Source for Antioxidant, Pro-Angiogenic, and Wound Healing Applications: In Silico Study Open
Background/Objectives: This study evaluated the potential of a polysaccharide (PCS) extracted from the brown alga Cystoseira spinosa as an antioxidant and anti-inflammatory agent. Collected off the coast of Alkhoms, Libya, PCS was investig…
View article: Potential Pharmacological Ability of a Novel Marine Polysaccharide Extracted from Tunisian Green Algae <i>Chaetomorpha aerea</i> to Accelerate Dermal Wound Healing in Rats
Potential Pharmacological Ability of a Novel Marine Polysaccharide Extracted from Tunisian Green Algae <i>Chaetomorpha aerea</i> to Accelerate Dermal Wound Healing in Rats Open
Background: Bacterial infection and oxidative stress generation are significant obstacles to dermal wound healing. The present study undertakes the isolation of a sulfated polysaccharide from the Tunisian green algal "Chaetomorpha aerea” n…
View article: Effectiveness of late and very late antivenom administration on recovery from snakebite-induced coagulopathy in French Guiana: a population-based study
Effectiveness of late and very late antivenom administration on recovery from snakebite-induced coagulopathy in French Guiana: a population-based study Open
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View article: Case Report: Acute myocarditis and cerebral infarction following Bothrops lanceolatus envenomation in Martinique: a case series
Case Report: Acute myocarditis and cerebral infarction following Bothrops lanceolatus envenomation in Martinique: a case series Open
Bothrops lanceolatus (Bl), a snake endemic to Martinique, is responsible for numerous envenomations annually, leading to severe complications such as thrombosis, necrosis, and hemorrhage. This case series investigates the link between Both…
View article: Evaluation of the Pro-Angiogenic Effect in Chicken Embryo Chorioallantoic Membrane (CAM) Model and the In Vivo Wound Healing Potential of the Moroccan Polysaccharide-Rich Algae <em>Osmundea pinnatifida</em>
Evaluation of the Pro-Angiogenic Effect in Chicken Embryo Chorioallantoic Membrane (CAM) Model and the In Vivo Wound Healing Potential of the Moroccan Polysaccharide-Rich Algae <em>Osmundea pinnatifida</em> Open
Various methods have been studied to speed up the wound healing process. Promoting the rapid development of blood vessels, also known as angiogenesis, is essential as this significantly accelerates skin regeneration. This study identified …
View article: A murine experimental model of the pulmonary thrombotic effect induced by the venom of the snake Bothrops lanceolatus
A murine experimental model of the pulmonary thrombotic effect induced by the venom of the snake Bothrops lanceolatus Open
Background The venom of Bothrops lanceolatus , a viperid species endemic to the Lesser Antillean Island of Martinique, induces thrombosis in a number of patients. Previous clinical observations indicate that thrombotic events are more comm…
View article: Physicochemical, structural, and biological properties of novel water-soluble polysaccharide derived from the Tunisian Hammada scoparia plant and its application on beef meat preservation
Physicochemical, structural, and biological properties of novel water-soluble polysaccharide derived from the Tunisian Hammada scoparia plant and its application on beef meat preservation Open
This work aims to characterize a novel water-soluble polysaccharide from Hammada scoparia leaves named PSP. The Infrared (FT-IR) and nuclear magnetic resonance (NMR) spectra confirmed the presence of different polysaccharide functio…
View article: Innate immune response in acute critical illness: a narrative review
Innate immune response in acute critical illness: a narrative review Open
Background Activation of innate immunity is a first line of host defense during acute critical illness (ACI) that aims to contain injury and avoid tissue damages. Aberrant activation of innate immunity may also participate in the occurrenc…
View article: Sex-related differences in toxic manifestations induced by Bothrops atrox venom in mice
Sex-related differences in toxic manifestations induced by Bothrops atrox venom in mice Open
Lancehead snakes of the genus Bothrops are responsible for 90% of the snakebites in Latin America. The objective of this study was to assess the LD50, physical, and hematological manifestations induced by B. atrox venom in male …
View article: Contribution of international cooperation in the management of the first documented case of Lonomia caterpillar envenoming (Lonomism) in Guyana
Contribution of international cooperation in the management of the first documented case of Lonomia caterpillar envenoming (Lonomism) in Guyana Open
Severe Lonomia caterpillar envenoming is an increasing hazard in South America. It can trigger severe coagulation disorders that can progress to systemic complications and death. We report the first documented case of severe Lonomia caterp…
View article: Histoplasmosis in Non-HIV Infected Patients: Another Neglected Infection in French Guiana
Histoplasmosis in Non-HIV Infected Patients: Another Neglected Infection in French Guiana Open
(1) Background: Only a few studies on histoplasmosis in immunocompetent patients have been reported in French Guiana. Therefore, we conducted a detailed clinical description of hospitalized patients suffering with histoplasmosis among non-…
View article: Anti-Vasculogenic, Antioxidant, and Anti-Inflammatory Activities of Sulfated Polysaccharide Derived from Codium tomentosum: Pharmacokinetic Assay
Anti-Vasculogenic, Antioxidant, and Anti-Inflammatory Activities of Sulfated Polysaccharide Derived from Codium tomentosum: Pharmacokinetic Assay Open
The purpose of this paper was to investigate the anti-inflammatory and anti-angiogenic activities of sulfated polysaccharide from C. tomentosum (PCT) using carrageenan (CARR)-induced paw edema in a rat model and anti-vasculogenic activity …
View article: Antibiotic Therapy and Prophylaxis for Snake-Bitten Patients
Antibiotic Therapy and Prophylaxis for Snake-Bitten Patients Open
View article: Bothrops lanceolatus Envenoming in Martinique: A Historical Perspective of the Clinical Effectiveness of Bothrofav Antivenom Treatment
Bothrops lanceolatus Envenoming in Martinique: A Historical Perspective of the Clinical Effectiveness of Bothrofav Antivenom Treatment Open
Bothrofav, a monospecific antivenom, was introduced in June 1991 and has shown excellent effectiveness against life-threatening and thrombotic complications of Bothrops lanceolatus envenoming. Because of the reoccurrence of cerebral stroke…
View article: Clinical and Epidemiological Characteristics of Severe Acute Adult Poisonings in French Amazonia: Urgent Need for a Toxicovigilance Monitoring Framework
Clinical and Epidemiological Characteristics of Severe Acute Adult Poisonings in French Amazonia: Urgent Need for a Toxicovigilance Monitoring Framework Open
Background: Acute poisonings (AP) are a significant public health problem, accounting for a high number of emergency department visits and thousands of deaths worldwide. This study aimed to assess the epidemiology of AP in an adult populat…
View article: Anti-Inflammatory and Immunomodulatory Properties of a Crude Polysaccharide Derived from Green Seaweed Halimeda tuna: Computational and Experimental Evidences
Anti-Inflammatory and Immunomodulatory Properties of a Crude Polysaccharide Derived from Green Seaweed Halimeda tuna: Computational and Experimental Evidences Open
In this study, we investigated for the first time the anti-inflammatory and immunomodulatory properties of crude polysaccharide (PSHT) extracted from green marine algae Halimeda tuna. PSHT exhibited anti-oxidant activity in vitro through s…
View article: Addressing snakebite envenoming as a One Health issue in the Caribbean
Addressing snakebite envenoming as a One Health issue in the Caribbean Open
View article: Mortality Trend of Severe COVID-19 in Under-Vaccinated Population Admitted to ICU in French Amazonia
Mortality Trend of Severe COVID-19 in Under-Vaccinated Population Admitted to ICU in French Amazonia Open
(1) Background: Until December 2021, French Guiana (FG), located in South America, faced four consecutive COVID-19 epidemic waves. This study sought to analyze the mortality trend of severe COVID-19 patients admitted to the referral ICU of…
View article: P474 IBD-Disk : Towards validating the classical Arabic version of the questionnaire ?
P474 IBD-Disk : Towards validating the classical Arabic version of the questionnaire ? Open
Background The IBD-Disk is a validated 10-question, self-administered visual questionnaire used to assess the inflammatory bowel disease (IBD) related disability. It has been translated into several languages and validated in different pop…
View article: P303 Determining the threshold for moderate-to-severe disability in inflammatory bowel disease using IBD-Disk
P303 Determining the threshold for moderate-to-severe disability in inflammatory bowel disease using IBD-Disk Open
Background The IBD-Disk is a validated 10-question visual scale, which has been shown to measure functional disability associated with inflammatory bowel diseases (IBD). The aim of this study is to assess the correlation between the IBD-Di…
View article: Mortality Trend of Severe COVID-19 in Under-Vaccinated Population Admitted to ICU in French Amazonia
Mortality Trend of Severe COVID-19 in Under-Vaccinated Population Admitted to ICU in French Amazonia Open
(1) Background: Until December 2021, French Guiana (FG), located in South America, faced four consecutive COVID-19 epidemic waves. This study sought to analyze the mortality trend of severe COVID-19 patients admitted to the referral ICU of…
View article: The effects of prolonged stress exposure on the brain of rats and insights to understand the impact of work-related stress on caregivers
The effects of prolonged stress exposure on the brain of rats and insights to understand the impact of work-related stress on caregivers Open
Introduction Stress exposure is a significant concern in the healthcare sector. This animal model study aims to reproduce caregivers’ working conditions and determine their impact on the brain. Method Twenty-four healthy male rats of the W…
View article: Mitigation of Hepatic Impairment with Polysaccharides from Red Alga Albidum corallinum Supplementation through Promoting the Lipid Profile and Liver Homeostasis in Tebuconazole-Exposed Rats
Mitigation of Hepatic Impairment with Polysaccharides from Red Alga Albidum corallinum Supplementation through Promoting the Lipid Profile and Liver Homeostasis in Tebuconazole-Exposed Rats Open
Sulfated polysaccharides from seaweed are highly active natural substances with valuable applications. In the present paper, attempts have been made to discuss the physicochemical and structural features of polysaccharides isolated from re…
View article: Mitigation of Hepatic Impairment with Polysaccharides from Red Alga <em>Alsidium corallinum</em> Supplementation through Promoting the Lipid Profile and Liver Homeostasis in Tebuconazole-Exposed Rats
Mitigation of Hepatic Impairment with Polysaccharides from Red Alga <em>Alsidium corallinum</em> Supplementation through Promoting the Lipid Profile and Liver Homeostasis in Tebuconazole-Exposed Rats Open
Sulfated polysaccharides from seaweed are highly active natural substances having valuable applications. In the present paper, attempts have been made to discuss the physicochemical and structural features of polysaccharides isolated from …
View article: Diagnostic and Management of Emphysematous Hepatitis with Emphasis on Biopathology
Diagnostic and Management of Emphysematous Hepatitis with Emphasis on Biopathology Open
Emphysematous hepatitis is a rare infectious disease, which corresponds to the presence of gas in the liver, without collection and after exclusion of vascular origin. This entity belongs to the group of emphysematous infections, whose phy…