Hiroyuki Kubo
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View article: Efficacy and safety of salvage chemotherapy with gemcitabine, oxaliplatin, and paclitaxel (GOP) for germ cell cancer in Japanese patients
Efficacy and safety of salvage chemotherapy with gemcitabine, oxaliplatin, and paclitaxel (GOP) for germ cell cancer in Japanese patients Open
View article: Short-term outcomes of triplet therapy in metastatic hormone-sensitive prostate cancer in older adults: a retrospective, single-center real-world cohort study
Short-term outcomes of triplet therapy in metastatic hormone-sensitive prostate cancer in older adults: a retrospective, single-center real-world cohort study Open
View article: P221 Complete resection of post-chemotherapy residual tumor could improve the prognosis in Non-Seminomatous Germ Cell Tumors (NSGCT)
P221 Complete resection of post-chemotherapy residual tumor could improve the prognosis in Non-Seminomatous Germ Cell Tumors (NSGCT) Open
View article: Mini-review: How can we protect the microbiota in our gut from antimicrobial agents during hematopoietic stem cell transplantation?
Mini-review: How can we protect the microbiota in our gut from antimicrobial agents during hematopoietic stem cell transplantation? Open
造血幹細胞移植では，血球減少期の感染対策として抗菌薬の予防内服を行う。これは移植中の重症感染症を予防し，予後を改善することが知られている一方で，抗菌薬投与による腸内細菌叢の攪乱が，移植後GVHDの発症や悪化を誘発するとの知見が最近得られている。2018年になってScienceに連続して掲載された3研究（trilogy）では，担がんマウスにおいて抗PD-1抗体の効果が腸内細菌叢の異同で異なることが示された。有意と考えられた腸内細菌種を接種するという介入の結果，抗PD-1抗体に…
View article: Compound heterozygous splice site variants in the SCLT1 gene highlight an additional candidate locus for Senior-Løken syndrome
Compound heterozygous splice site variants in the SCLT1 gene highlight an additional candidate locus for Senior-Løken syndrome Open
Senior Løken syndrome (SLS) is a heterogeneous disorder characterized by severe retinal degenerations and juvenile-onset nephronophthisis. Genetic variants in ten different genes have been reported as the causes of SLS. Clinical evaluation…
View article: Surgery for gastroesophageal reflux disease with Gaucher disease type 2
Surgery for gastroesophageal reflux disease with Gaucher disease type 2 Open
Gaucher disease, the most common lysosomal storage disease, is sometimes complicated with gastroesophageal reflux disease (GERD). The present patient was a 136‐day‐old Japanese boy with Gaucher disease type 2. Enzyme replacement therapy an…
View article: Generation of electromagnetic waves from 0.3 to 1.6 terahertz with a high-Tc superconducting Bi2Sr2CaCu2O8+<i>δ</i> intrinsic Josephson junction emitter
Generation of electromagnetic waves from 0.3 to 1.6 terahertz with a high-Tc superconducting Bi2Sr2CaCu2O8+<i>δ</i> intrinsic Josephson junction emitter Open
To obtain higher power P and frequency f emissions from the intrinsic Josephson junctions in a high-Tc superconducting Bi2Sr2CaCu2O8+δ single crystal, we embedded a rectangular stand-alone mesa of that material in a sandwich structure to a…
View article: <scp>HDlive</scp> imaging of meconium peritonitis
<span>HDlive</span> imaging of meconium peritonitis Open
Prenatal two-dimensional (2D) sonographic diagnostic criteria for meconium peritonitis include polyhydramnios, bowel dilatation, abdominal calcification or echogenic mass and fetal ascites1. However, its diagnosis is still challenging, not…