Hayley Barnes
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View article: 8279516 Autoimmune disease and prevalence of autoantibodies amongst workers exposed to high-dose respirable crystalline silica
8279516 Autoimmune disease and prevalence of autoantibodies amongst workers exposed to high-dose respirable crystalline silica Open
View article: Silicosis research priorities for health care, research, and health and safety professionals, and for people exposed to silica in Australia: a research priority setting exercise
Silicosis research priorities for health care, research, and health and safety professionals, and for people exposed to silica in Australia: a research priority setting exercise Open
Objectives To identify the silicosis research priorities of people living with silicosis, workers at risk of silicosis, their partners and caregivers, and of health professionals and researchers. Study design Research priority setting exer…
View article: Patient-reported outcome measures for cough used in interstitial lung disease: a systematic review
Patient-reported outcome measures for cough used in interstitial lung disease: a systematic review Open
Introduction Validated and reliable patient-reported outcome measures (PROMs) are recommended to assess the severity and impact of cough in interstitial lung disease (ILD). We systematically reviewed the literature to identify PROMs for co…
View article: Patient and healthcare professional perspectives on telehealth in the care of interstitial lung disease
Patient and healthcare professional perspectives on telehealth in the care of interstitial lung disease Open
Background While telehealth has been used for specialist care during the COVID-19 pandemic, its benefits and barriers to use for delivering care in interstitial lung disease (ILD) remain unclear. We aimed to explore perspectives of patient…
View article: Inhalational exposures associated with risk of interstitial lung disease: a systematic review and meta-analysis
Inhalational exposures associated with risk of interstitial lung disease: a systematic review and meta-analysis Open
Rationale Inhalational exposures are associated with risk of developing interstitial lung disease (ILD), yet the relationship between specific exposures and ILD is poorly characterised. Objective Identify inhalational exposures associated …
View article: Approach to Lung Transplantation in Pulmonary Arterial Hypertension: A Delphi Consensus on Behalf of the Transplant Task Force of the Pulmonary Vascular Research Institute
Approach to Lung Transplantation in Pulmonary Arterial Hypertension: A Delphi Consensus on Behalf of the Transplant Task Force of the Pulmonary Vascular Research Institute Open
Lung transplantation is indicated for selected patients with advanced pulmonary arterial hypertension (PAH). We used a modified Delphi process to develop recommendations on care of patients with PAH undergoing lung transplantation. This De…
View article: The Rapid Rise of Silicosis in Victoria, Australia Associated With Artificial Stone Countertop Industry Work
The Rapid Rise of Silicosis in Victoria, Australia Associated With Artificial Stone Countertop Industry Work Open
Background The fabrication and installation of artificial (engineered) stone countertops is a relatively new cause of silicosis. Our aim was to investigate silicosis rates in Victoria, Australia, and the association with stone countertop i…
View article: Silicosis—Where to from here?
Silicosis—Where to from here? Open
View article: Efficacy and safety of a whole lung lavage program for artificial stone silicosis
Efficacy and safety of a whole lung lavage program for artificial stone silicosis Open
WLL for artificial stone silicosis is safe in an expert centre who has experience in performing WLL in this population, and there may be limited benefit in selected patients. Further research is required to select those who will derive the…
View article: Current surgical management of chronic thromboembolic pulmonary disease
Current surgical management of chronic thromboembolic pulmonary disease Open
Chronic thromboembolic pulmonary disease (CTEPD) with or without pulmonary hypertension (PH) is an important potential consequence of venous thromboembolic disease. Untreated CTEPD with pulmonary hypertension (CTEPH) is associated with hig…
View article: Steroid therapy in acute exacerbation of fibrotic interstitial lung disease
Steroid therapy in acute exacerbation of fibrotic interstitial lung disease Open
Background and Objective Evidence for the benefit of steroid therapy in acute exacerbations (AEs) of idiopathic pulmonary fibrosis (IPF) is limited; however, they remain a cornerstone of management in other fibrotic interstitial lung disea…
View article: Chest x‐ray has low sensitivity to detect silicosis in artificial stone benchtop industry workers
Chest x‐ray has low sensitivity to detect silicosis in artificial stone benchtop industry workers Open
Background and Objective Chest x‐ray (CXR) remains a core component of health monitoring guidelines for workers at risk of exposure to crystalline silica. There has however been a lack of evidence regarding the sensitivity of CXR to detect…
View article: Scoping review of exposure questionnaires and surveys in interstitial lung disease
Scoping review of exposure questionnaires and surveys in interstitial lung disease Open
Background Many interstitial lung diseases (ILDs) have clear causal relationships with environmental and occupational exposures. Exposure identification can assist with diagnosis, understanding disease pathogenesis, prognostication and pre…
View article: Multidisciplinary meeting review in nonsmall cell lung cancer: a systematic review and meta-analysis
Multidisciplinary meeting review in nonsmall cell lung cancer: a systematic review and meta-analysis Open
Background: Lung cancer diagnosis, staging and treatment may be enhanced by multidisciplinary participation and presentation in multidisciplinary meetings (MDM). We performed a systematic review and meta-analysis to explore literature evid…
View article: Changing trends in mesothelioma: Important lessons for an occupational disease registry
Changing trends in mesothelioma: Important lessons for an occupational disease registry Open
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View article: Tocilizumab in Patients with Systemic Sclerosis–associated Interstitial Lung Disease: A Systematic Review and Meta-Analysis
Tocilizumab in Patients with Systemic Sclerosis–associated Interstitial Lung Disease: A Systematic Review and Meta-Analysis Open
Background: The American Thoracic Society (ATS) convened an international, multidisciplinary panel to develop clinical practice guidelines for the treatment of systemic sclerosis-associated interstitial lung disease (SSc-ILD). Ob…
View article: Rituximab in Patients with Systemic Sclerosis–associated Interstitial Lung Disease: A Systematic Review and Meta-Analysis
Rituximab in Patients with Systemic Sclerosis–associated Interstitial Lung Disease: A Systematic Review and Meta-Analysis Open
Background: The American Thoracic Society convened an international, multidisciplinary panel to develop clinical practice guidelines for the treatment of systemic sclerosis-associated interstitial lung disease (SSc-ILD). Objectiv…
View article: Nintedanib Therapy Alone and Combined with Mycophenolate in Patients with Systemic Sclerosis–associated Interstitial Lung Disease: Systematic Reviews and Meta-analysis
Nintedanib Therapy Alone and Combined with Mycophenolate in Patients with Systemic Sclerosis–associated Interstitial Lung Disease: Systematic Reviews and Meta-analysis Open
Background: The American Thoracic Society convened an international multidisciplinary panel to develop clinical practice guidelines for the treatment of systemic sclerosis-associated interstitial lung disease (SSc-ILD). Objective…
View article: Treatment of Systemic Sclerosis–associated Interstitial Lung Disease: Evidence-based Recommendations. An Official American Thoracic Society Clinical Practice Guideline
Treatment of Systemic Sclerosis–associated Interstitial Lung Disease: Evidence-based Recommendations. An Official American Thoracic Society Clinical Practice Guideline Open
Background: Interstitial lung disease (ILD) is a significant cause of morbidity and mortality in patients with systemic sclerosis (SSc). To date, clinical practice guidelines regarding treatment for patients with SSc-ILD are primari…
View article: P17.03.A MAGIC-G1: A PHASE 1 DOSE-ESCALATION TRIAL OF WEEKLY INTRATUMORAL ADMINISTRATION OF THE SOLUBILISED FORMULATION OF PANOBINOSTAT (MTX110) IN PATIENTS WITH RECURRENT GLIOBLASTOMA (RGBM)
P17.03.A MAGIC-G1: A PHASE 1 DOSE-ESCALATION TRIAL OF WEEKLY INTRATUMORAL ADMINISTRATION OF THE SOLUBILISED FORMULATION OF PANOBINOSTAT (MTX110) IN PATIENTS WITH RECURRENT GLIOBLASTOMA (RGBM) Open
BACKGROUND One of the biggest challenges in treating rGBM is achieving high local drug concentration. Convection enhanced delivery (CED) is a ‘direct-to-brain’ drug delivery method that previously demonstrated its usefulness in overcoming …
View article: Machine learning in radiology: the new frontier in interstitial lung diseases
Machine learning in radiology: the new frontier in interstitial lung diseases Open
Challenges for the effective management of interstitial lung diseases (ILDs) include difficulties with the early detection of disease, accurate prognostication with baseline data, and accurate and precise response to therapy. The purpose o…
View article: Clinical utility of a standardized chronic hypersensitivity pneumonitis exposure questionnaire
Clinical utility of a standardized chronic hypersensitivity pneumonitis exposure questionnaire Open
Background and Objective Identification of an exposure is integral to the diagnosis, management, and prognostication of chronic hypersensitivity pneumonitis (CHP). Standardized questionnaires may aid in the identification of exposures, how…
View article: Development of a Knowledge-sharing Website for Hypersensitivity Pneumonitis Exposures
Development of a Knowledge-sharing Website for Hypersensitivity Pneumonitis Exposures Open
HPLung.com is a novel knowledge-sharing tool that addresses barriers of accessibility, contemporaneity, efficient evidence synthesis, and making the best use of technological platforms to improve the exposure assessment of those suspected …
View article: 84 Effectiveness of BOSA (Brief Observation of Symptoms of Autism) as an Alternative Diagnostic Tool for ASD (Autistic Spectrum Disorder) During the Coronavirus Pandemic – A Retrospective Audit
84 Effectiveness of BOSA (Brief Observation of Symptoms of Autism) as an Alternative Diagnostic Tool for ASD (Autistic Spectrum Disorder) During the Coronavirus Pandemic – A Retrospective Audit Open
Aims By necessity, our trust was unable to complete gold standard ADOS (Autism Diagnostic Observation Schedule) assessments as part of the ASD diagnostic pathway during the Coronavirus pandemic. We, therefore, implemented the BOSA as a sto…
View article: Composite Lung Transplant Suitability Score (CLaSS): A Novel Predictor of Survival Following Lung Transplantation
Composite Lung Transplant Suitability Score (CLaSS): A Novel Predictor of Survival Following Lung Transplantation Open
View article: Antifibrotic therapies for idiopathic pulmonary fibrosis
Antifibrotic therapies for idiopathic pulmonary fibrosis Open
This is a protocol for a Cochrane Review (intervention). The objectives are as follows: To investigate the efficacy and safety of antifibrotic drugs in individuals with idiopathic pulmonary fibrosis.
View article: The hidden history of hypersensitivity pneumonitis
The hidden history of hypersensitivity pneumonitis Open
Hypersensitivity pneumonitis (HP) is a relatively new construct, first reported in the early 20th century, despite major aetiological factors (farming, bird husbandry) having been part of human activities for millennia. Initial confirmed H…
View article: Benefits of a virtual interstitial lung disease <scp>multidisciplinary</scp> meeting in the face of <scp>COVID</scp>‐19
Benefits of a virtual interstitial lung disease <span>multidisciplinary</span> meeting in the face of <span>COVID</span>‐19 Open
The novel coronavirus pandemic continues to have a dramatic impact upon all aspects of health care. Interstitial lung disease (ILD) clinicians and patients alike are faced with new challenges as a result of the threat imposed by coronaviru…
View article: Pharmacological Interventions for Breathlessness—Absence of Effect or Absence of Evidence?
Pharmacological Interventions for Breathlessness—Absence of Effect or Absence of Evidence? Open
Josephine L. Feliciano, MD; Julie M. Waldfogel, PharmD, BCGP, CPE; Ritu Sharma, BSc; Allen Zhang, BS; Arjun Gupta, MD; Ramy Sedhom, MD; Jeff Day, MD, MA; Eric B. Bass, MD, MPH; Sydney M. Dy, MD, MS
View article: Exposure Assessment Tools for Hypersensitivity Pneumonitis. An Official American Thoracic Society Workshop Report
Exposure Assessment Tools for Hypersensitivity Pneumonitis. An Official American Thoracic Society Workshop Report Open
This report is based on proceedings from the Exposure Assessment Tools for Hypersensitivity Pneumonitis (HP) Workshop, sponsored by the American Thoracic Society, that took place on May 18, 2019, in Dallas, Texas. The workshop was initiate…