Hayriye Ecem Yelkenci
YOU?
Author Swipe
View article: Exploring the Proteomic Signature of Diabetic Nephropathy: Implications for Early Diagnosis and Treatment
Exploring the Proteomic Signature of Diabetic Nephropathy: Implications for Early Diagnosis and Treatment Open
Diabetic nephropathy (DN) is a leading cause of end-stage renal disease, characterized by progressive kidney dysfunction. Early detection and targeted therapies remain key challenges in managing DN. This study aims to identify proteomic al…
View article: Intergenerational Conditioning via Intermittent Parental Hypoxia Confers Stroke Resilience in Offspring
Intergenerational Conditioning via Intermittent Parental Hypoxia Confers Stroke Resilience in Offspring Open
Background and Aims Intergenerational disease transmission, where parental exposures or experiences influence disease susceptibility in offspring, may represent a crucial layer of stroke risk that extends beyond genetics alone. Environment…
View article: Proteomic Data and Drug Implications for Cerebral Microvascular Endothelial Cells Under Varying Oxygen Levels
Proteomic Data and Drug Implications for Cerebral Microvascular Endothelial Cells Under Varying Oxygen Levels Open
Hyperoxia in standard cell cultures (18 kPa O2) imposes cellular oxidative stress, potentially skewing research and drug screening outcomes. Cerebral microvascular endothelial cells (hCMEC/D3) experience no more than 7 kPa O2 in vivo. In t…
View article: Identification of PDE10A related proteins via proteomic analysis
Identification of PDE10A related proteins via proteomic analysis Open
Objective: Phosphodiesterase 10A (PDE10A) regulates the expression of secondary messengers of cyclic adenosine monophosphate and cyclic guanosine monophosphate, which control several intracellular signaling pathways. Recently, deactivation…