Zhili He
YOU?
Author Swipe
View article: Microbially-mediated halogenation and dehalogenation cycling of organohalides in the ocean
Microbially-mediated halogenation and dehalogenation cycling of organohalides in the ocean Open
Microbially mediated organohalide cycling in the ocean has profound implications for global biogeochemical cycles and climate, but the geographic distribution and diversity of the halogenation-dehalogenation cycling microorganisms remain u…
View article: B7 Family Molecule VSIG4 Regulates Pulmonary Anti-Influenza Immune Responses via C-Type Lectin Signal Pathway
B7 Family Molecule VSIG4 Regulates Pulmonary Anti-Influenza Immune Responses via C-Type Lectin Signal Pathway Open
Background: As the member of the B7 family, V-set and immunoglobulin domain-containing 4 (VSIG4) plays an essential role in regulating immune responses against bacterial infection, autoimmune disease, and chronic viral infection. However, …
View article: Amoebae contribute to the diversity and fate of antibiotic resistance genes in drinking water system
Amoebae contribute to the diversity and fate of antibiotic resistance genes in drinking water system Open
Free-living amoebae represent a significant eukaryotic group that thrives in drinking water systems, posing considerable risks to water quality due to their inherent pathogenicity and associations with various microorganisms. However, the …
View article: Transcriptomic and metabolomic insights into light-mediated unicellular-to-multicellular transition in <i>Dictyostelium discoideum</i>
Transcriptomic and metabolomic insights into light-mediated unicellular-to-multicellular transition in <i>Dictyostelium discoideum</i> Open
Dictyostelium discoideum is a social amoeba that transitions from unicellular to multicellular forms in response to environmental signals, making it an intriguing model for studying cell aggregation and differentiation. Although previous s…
View article: Ace2 mutation disrupts amino acid absorption, impairs growth, and alters microbiota dynamics in zebrafish
Ace2 mutation disrupts amino acid absorption, impairs growth, and alters microbiota dynamics in zebrafish Open
Angiotensin-converting enzyme 2 (Ace2) is a well-studied enzyme with important physiological functions in mammals. However, its roles in non-mammalian animals remain largely unexplored. This study investigates the function of Ace2 in zebra…
View article: Comparative transcriptomic and genomic analysis of tumor cells in the marginal and center regions of tumor nests in human hepatocellular carcinoma
Comparative transcriptomic and genomic analysis of tumor cells in the marginal and center regions of tumor nests in human hepatocellular carcinoma Open
Background The tumor nests in solid tumors, including hepatocellular carcinoma (HCC), possess tumor-initiating potential, with the capacity to metastasize and form new metastatic lesions. However, the biological characteristics and heterog…
View article: The efficacy of Akkermansia muciniphila YGMCC2602-derived postbiotics in skin repair
The efficacy of Akkermansia muciniphila YGMCC2602-derived postbiotics in skin repair Open
Skin aging, wrinkles, dryness, and inflammation have been of great concern and the development of non-toxic natural skin care products is of great importance. In this study, we investigated for the role of three postbiotics (cell-free supe…
View article: Interaction Between Microbiota and Immunity: Molecular Mechanisms, Biological Functions, Diseases, and New Therapeutic Opportunities
Interaction Between Microbiota and Immunity: Molecular Mechanisms, Biological Functions, Diseases, and New Therapeutic Opportunities Open
The microbiota is pivotal for our health. It includes different phyla like Bacteroidetes, Firmicutes, Actinobacteria, Proteobacteria, Fusobacteria, and Verrucomicrobia. The interaction between microbiota and immunity shares a bidirectional…
View article: Microbial responses to ocean deoxygenation: Revisiting the impacts on organic carbon cycling
Microbial responses to ocean deoxygenation: Revisiting the impacts on organic carbon cycling Open
Ocean deoxygenation is impacting and will also in the future impact fundamental biogeochemical cycles. This review explores the ecological functions of microbes under hypoxic and anoxic conditions, emphasizing their critical roles in carbo…
View article: Global diversity and distribution of antibiotic resistance genes in human wastewater treatment systems
Global diversity and distribution of antibiotic resistance genes in human wastewater treatment systems Open
Antibiotic resistance poses a significant threat to human health, and wastewater treatment plants (WWTPs) are important reservoirs of antibiotic resistance genes (ARGs). Here, we analyze the antibiotic resistomes of 226 activated sludge sa…
View article: Modest functional diversity decline and pronounced composition shifts of microbial communities in a mixed waste-contaminated aquifer
Modest functional diversity decline and pronounced composition shifts of microbial communities in a mixed waste-contaminated aquifer Open
View article: Advancements and Challenges of Multimodal Models in Medical Applications
Advancements and Challenges of Multimodal Models in Medical Applications Open
Multimodal models have demonstrated significant potential in the medical field integrating information from various modalities such as images and text to improve understanding and reasoning. This paper provides a comprehensive review of th…
View article: Seasonal Variations in Macrobenthos Communities and Their Relationship with Environmental Factors in the Alpine Yuqu River
Seasonal Variations in Macrobenthos Communities and Their Relationship with Environmental Factors in the Alpine Yuqu River Open
This study investigated the spatial and temporal variations of macrobenthos community structure in the Yuqu River Basin during the dry and wet seasons due to environmental factors. This study quantified the independent and interactive cont…
View article: Microbial biotechnology: from synthetic biology to synthetic ecology
Microbial biotechnology: from synthetic biology to synthetic ecology Open
View article: Noise-resistant optomechanical entanglement via cross-Kerr effect
Noise-resistant optomechanical entanglement via cross-Kerr effect Open
View article: The Vertical Distribution and Metabolic Versatility of Complete Ammonia Oxidizing Communities of Mangrove Sediments
The Vertical Distribution and Metabolic Versatility of Complete Ammonia Oxidizing Communities of Mangrove Sediments Open
View article: Application value of metagenomic next-generation sequencing of bronchoalveolar lavage fluid in pathogen detection and diagnostic efficiency of acute exacerbation of bronchiectasis
Application value of metagenomic next-generation sequencing of bronchoalveolar lavage fluid in pathogen detection and diagnostic efficiency of acute exacerbation of bronchiectasis Open
BALF mNGS demonstrates clear advantages over conventional methods in pathogen detection for AE-bronchiectasis, offering significantly better detection rates and diagnostic efficiency.
View article: DDIM sampling for Generative AIBIM, a faster intelligent structural design framework
DDIM sampling for Generative AIBIM, a faster intelligent structural design framework Open
Generative AIBIM, a successful structural design pipeline, has proven its ability to intelligently generate high-quality, diverse, and creative shear wall designs that are tailored to specific physical conditions. However, the current modu…
View article: A salt-tolerant growth-promoting phyllosphere microbial combination from mangrove plants and its mechanism for promoting salt tolerance in rice
A salt-tolerant growth-promoting phyllosphere microbial combination from mangrove plants and its mechanism for promoting salt tolerance in rice Open
This study advances our understanding of the mutualistic and symbiotic relationships between mangrove species and their phyllosphere microbial communities. It offers a paradigm for exploring agricultural beneficial microbial resources from…
View article: Pneumonia image classification using convolutional neural network
Pneumonia image classification using convolutional neural network Open
Throughout history, humanity has continually faced numerous unforeseen health crises, thereby emphasizing the utmost significance of harnessing cutting-edge technology and scientific approaches to proactively anticipate and tackle potentia…
View article: Publisher Correction: Mechanisms underlying the interactions and adaptability of nitrogen removal microorganisms in freshwater sediments
Publisher Correction: Mechanisms underlying the interactions and adaptability of nitrogen removal microorganisms in freshwater sediments Open
View article: Mechanisms underlying the interactions and adaptability of nitrogen removal microorganisms in freshwater sediments
Mechanisms underlying the interactions and adaptability of nitrogen removal microorganisms in freshwater sediments Open
View article: Unraveling the important role of comammox Nitrospira to nitrification in the coastal aquaculture system
Unraveling the important role of comammox Nitrospira to nitrification in the coastal aquaculture system Open
Increasing nitrogen (N) input to coastal ecosystems poses a serious environmental threat. It is important to understand the responses and feedback of N removal microbial communities, particularly nitrifiers including the newly recognized c…
View article: Anti-obesity effects of Bifidobacterium lactis YGMCC2013 by promoting adipocyte thermogenesis and beige remodelling in association with gut microbiota
Anti-obesity effects of Bifidobacterium lactis YGMCC2013 by promoting adipocyte thermogenesis and beige remodelling in association with gut microbiota Open
Obesity, a global public health challenge, is closely associated with gut microbiota alterations. Probiotics have the potential to prevent obesity, but their effectiveness can vary depending on the specific strain. This study focused on ev…
View article: Quantification of microbially induced soil N2O emissions by an inhibitory cocktail in mountain forest ecosystems
Quantification of microbially induced soil N2O emissions by an inhibitory cocktail in mountain forest ecosystems Open
Simultaneously quantifying soil N2O emissions contributed by different microbial groups and revealing the underlying mechanisms have long been challenging but fundamental to understanding terrestrial nitrogen cycling. Here, a novel inhibit…
View article: An optimized culturomics strategy for isolation of human milk microbiota
An optimized culturomics strategy for isolation of human milk microbiota Open
Viable microorganisms and a diverse microbial ecosystem found in human milk play a crucial role in promoting healthy immune system and shaping the microbial community in the infant’s gut. Culturomics is a method to obtain a comprehensive r…
View article: Impacts of Vaccination and Severe Acute Respiratory Syndrome Coronavirus 2 Variants Alpha and Delta on Coronavirus Disease 2019 Transmission Dynamics in Four Metropolitan Areas of the United States
Impacts of Vaccination and Severe Acute Respiratory Syndrome Coronavirus 2 Variants Alpha and Delta on Coronavirus Disease 2019 Transmission Dynamics in Four Metropolitan Areas of the United States Open
View article: Topological and metagenomic evidence for intensified bacterial-fungal associations in mangrove root interior
Topological and metagenomic evidence for intensified bacterial-fungal associations in mangrove root interior Open
Plant roots host a repertoire of bacteria and fungi, whose ecological interactions could improve their functions and plant performance. However, potential interactions and underlying mechanisms remain largely unknown in root-associated mic…
View article: Environmental stress mediates groundwater microbial community assembly
Environmental stress mediates groundwater microbial community assembly Open
View article: Soil-Dependent Responses of Bacterial Communities, Phosphorus and Carbon Turnover to Uranium Stress in Different Soil Ecosystems
Soil-Dependent Responses of Bacterial Communities, Phosphorus and Carbon Turnover to Uranium Stress in Different Soil Ecosystems Open