Helen Moinova
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View article: NONENDOSCOPIC DETECTION OF BARRETT’S ESOPHAGUS IN PATIENTS WITHOUT GERD SYMPTOMS
NONENDOSCOPIC DETECTION OF BARRETT’S ESOPHAGUS IN PATIENTS WITHOUT GERD SYMPTOMS Open
Background Screening efforts for Barrett’s Esophagus (BE) predominantly focus on performing upper endoscopy (EGD) on patients with gastroesophageal reflux disease (GERD) symptoms who have additional risk factors for BE. However, cost and i…
View article: Multicenter, Prospective Trial of Nonendoscopic Biomarker-Driven Detection of Barrett's Esophagus and Esophageal Adenocarcinoma
Multicenter, Prospective Trial of Nonendoscopic Biomarker-Driven Detection of Barrett's Esophagus and Esophageal Adenocarcinoma Open
INTRODUCTION: Preliminary data suggest that an encapsulated balloon (EsoCheck), coupled with a 2 methylated DNA biomarker panel (EsoGuard), detects Barrett's esophagus (BE) and esophageal adenocarcinoma (EAC) with high accuracy. The initia…
View article: Patients With Esophageal Adenocarcinoma With Prior Gastroesophageal Reflux Disease Symptoms Are Similar to Those Without Gastroesophageal Reflux Disease: A Cross-Sectional Study
Patients With Esophageal Adenocarcinoma With Prior Gastroesophageal Reflux Disease Symptoms Are Similar to Those Without Gastroesophageal Reflux Disease: A Cross-Sectional Study Open
INTRODUCTION: A substantial proportion of patients with esophageal adenocarcinoma (EAC) do not report gastroesophageal reflux disease (GERD) symptoms. This study aimed to compare the risk factor profiles and cancer stage at presentation of…
View article: NON-ENDOSCOPIC ESOPHAGEAL SAMPLING DEVICE AND BIOMARKER PANEL FOR DETECTION OF BARRETT’S ESOPHAGUS (BE) AND ESOPHAGEAL ADENOCARCINOMA (EAC)
NON-ENDOSCOPIC ESOPHAGEAL SAMPLING DEVICE AND BIOMARKER PANEL FOR DETECTION OF BARRETT’S ESOPHAGUS (BE) AND ESOPHAGEAL ADENOCARCINOMA (EAC) Open
BACKGROUND We previously reported an encapsulated balloon (EsoCheck TM , EC), which selectively samples the distal esophagus, that coupled with a two methylated DNA biomarker panel (EsoGuard TM , EG), detected Barrett’s esophagus (BE) and …
View article: Supplementary Figure 1 from Aberrant Vimentin Methylation Is Characteristic of Upper Gastrointestinal Pathologies
Supplementary Figure 1 from Aberrant Vimentin Methylation Is Characteristic of Upper Gastrointestinal Pathologies Open
PDF file - 41K
View article: Data from Aberrant Vimentin Methylation Is Characteristic of Upper Gastrointestinal Pathologies
Data from Aberrant Vimentin Methylation Is Characteristic of Upper Gastrointestinal Pathologies Open
Background: We have previously established aberrant DNA methylation of vimentin exon-1 (VIM methylation) as a common epigenetic event in colon cancer and as a biomarker for detecting colon neoplasia. We now examine vimentin methylation in …
View article: Data from Novel DNA Methylation Biomarker Panel for Detection of Esophageal Adenocarcinoma and High-Grade Dysplasia
Data from Novel DNA Methylation Biomarker Panel for Detection of Esophageal Adenocarcinoma and High-Grade Dysplasia Open
Purpose:Current endoscopy-based screening and surveillance programs have not been proven effective at decreasing esophageal adenocarcinoma (EAC) mortality, creating an unmet need for effective molecular tests for early detection of this hi…
View article: Supplementary Figure from Novel DNA Methylation Biomarker Panel for Detection of Esophageal Adenocarcinoma and High-Grade Dysplasia
Supplementary Figure from Novel DNA Methylation Biomarker Panel for Detection of Esophageal Adenocarcinoma and High-Grade Dysplasia Open
Supplementary Figure from Novel DNA Methylation Biomarker Panel for Detection of Esophageal Adenocarcinoma and High-Grade Dysplasia
View article: Supplementary Table 1 from Aberrant Vimentin Methylation Is Characteristic of Upper Gastrointestinal Pathologies
Supplementary Table 1 from Aberrant Vimentin Methylation Is Characteristic of Upper Gastrointestinal Pathologies Open
PDF file - 189K
View article: Data from Novel DNA Methylation Biomarker Panel for Detection of Esophageal Adenocarcinoma and High-Grade Dysplasia
Data from Novel DNA Methylation Biomarker Panel for Detection of Esophageal Adenocarcinoma and High-Grade Dysplasia Open
Purpose:Current endoscopy-based screening and surveillance programs have not been proven effective at decreasing esophageal adenocarcinoma (EAC) mortality, creating an unmet need for effective molecular tests for early detection of this hi…
View article: Supplemental Table S2 from Methylated <i>B3GAT2</i> and <i>ZNF793</i> Are Potential Detection Biomarkers for Barrett's Esophagus
Supplemental Table S2 from Methylated <i>B3GAT2</i> and <i>ZNF793</i> Are Potential Detection Biomarkers for Barrett's Esophagus Open
Supplemental Table S2: Methylation levels for B3GAT2 and ZNF793 from Human Methylation450 arrays.
View article: Data from Methylated <i>B3GAT2</i> and <i>ZNF793</i> Are Potential Detection Biomarkers for Barrett's Esophagus
Data from Methylated <i>B3GAT2</i> and <i>ZNF793</i> Are Potential Detection Biomarkers for Barrett's Esophagus Open
Background: Barrett's esophagus (BE) is a preneoplastic condition in which normal esophageal squamous epithelium (SQ) is replaced by specialized intestinal metaplasia. It is the presumed precursor for esophageal adenocarcinoma (EAC) as wel…
View article: Supplementary Table 2 from Aberrant Vimentin Methylation Is Characteristic of Upper Gastrointestinal Pathologies
Supplementary Table 2 from Aberrant Vimentin Methylation Is Characteristic of Upper Gastrointestinal Pathologies Open
PDF file - 147K
View article: Supplemental Table S2 from Methylated <i>B3GAT2</i> and <i>ZNF793</i> Are Potential Detection Biomarkers for Barrett's Esophagus
Supplemental Table S2 from Methylated <i>B3GAT2</i> and <i>ZNF793</i> Are Potential Detection Biomarkers for Barrett's Esophagus Open
Supplemental Table S2: Methylation levels for B3GAT2 and ZNF793 from Human Methylation450 arrays.
View article: Supplementary Table 2 from Aberrant Vimentin Methylation Is Characteristic of Upper Gastrointestinal Pathologies
Supplementary Table 2 from Aberrant Vimentin Methylation Is Characteristic of Upper Gastrointestinal Pathologies Open
PDF file - 147K
View article: Supplemental Table S1 from Methylated <i>B3GAT2</i> and <i>ZNF793</i> Are Potential Detection Biomarkers for Barrett's Esophagus
Supplemental Table S1 from Methylated <i>B3GAT2</i> and <i>ZNF793</i> Are Potential Detection Biomarkers for Barrett's Esophagus Open
Supplemental Table S1. Clinical Characteristics of Samples
View article: Supplementary Data from Novel DNA Methylation Biomarker Panel for Detection of Esophageal Adenocarcinoma and High-Grade Dysplasia
Supplementary Data from Novel DNA Methylation Biomarker Panel for Detection of Esophageal Adenocarcinoma and High-Grade Dysplasia Open
Supplementary Data from Novel DNA Methylation Biomarker Panel for Detection of Esophageal Adenocarcinoma and High-Grade Dysplasia
View article: Supplementary Data from Novel DNA Methylation Biomarker Panel for Detection of Esophageal Adenocarcinoma and High-Grade Dysplasia
Supplementary Data from Novel DNA Methylation Biomarker Panel for Detection of Esophageal Adenocarcinoma and High-Grade Dysplasia Open
Supplementary Data from Novel DNA Methylation Biomarker Panel for Detection of Esophageal Adenocarcinoma and High-Grade Dysplasia
View article: Supplemental Figures from Methylated <i>B3GAT2</i> and <i>ZNF793</i> Are Potential Detection Biomarkers for Barrett's Esophagus
Supplemental Figures from Methylated <i>B3GAT2</i> and <i>ZNF793</i> Are Potential Detection Biomarkers for Barrett's Esophagus Open
Supplemental Figure S1: Assessment of precision of pyrosequencing assay for methylated B3GAT2 and ZNF793. Supplemental Figure S2: Correlation of pyrosequencing results with HM450 array beta values.Supplemental Figure S3: Methylation status…
View article: Supplemental Figures from Methylated <i>B3GAT2</i> and <i>ZNF793</i> Are Potential Detection Biomarkers for Barrett's Esophagus
Supplemental Figures from Methylated <i>B3GAT2</i> and <i>ZNF793</i> Are Potential Detection Biomarkers for Barrett's Esophagus Open
Supplemental Figure S1: Assessment of precision of pyrosequencing assay for methylated B3GAT2 and ZNF793. Supplemental Figure S2: Correlation of pyrosequencing results with HM450 array beta values.Supplemental Figure S3: Methylation status…
View article: Supplementary Figure 2 from Aberrant Vimentin Methylation Is Characteristic of Upper Gastrointestinal Pathologies
Supplementary Figure 2 from Aberrant Vimentin Methylation Is Characteristic of Upper Gastrointestinal Pathologies Open
PDF file - 43K
View article: Supplementary Figure 2 from Aberrant Vimentin Methylation Is Characteristic of Upper Gastrointestinal Pathologies
Supplementary Figure 2 from Aberrant Vimentin Methylation Is Characteristic of Upper Gastrointestinal Pathologies Open
PDF file - 43K
View article: Data from Methylated <i>B3GAT2</i> and <i>ZNF793</i> Are Potential Detection Biomarkers for Barrett's Esophagus
Data from Methylated <i>B3GAT2</i> and <i>ZNF793</i> Are Potential Detection Biomarkers for Barrett's Esophagus Open
Background: Barrett's esophagus (BE) is a preneoplastic condition in which normal esophageal squamous epithelium (SQ) is replaced by specialized intestinal metaplasia. It is the presumed precursor for esophageal adenocarcinoma (EAC) as wel…
View article: Supplementary Figure from Novel DNA Methylation Biomarker Panel for Detection of Esophageal Adenocarcinoma and High-Grade Dysplasia
Supplementary Figure from Novel DNA Methylation Biomarker Panel for Detection of Esophageal Adenocarcinoma and High-Grade Dysplasia Open
Supplementary Figure from Novel DNA Methylation Biomarker Panel for Detection of Esophageal Adenocarcinoma and High-Grade Dysplasia
View article: Supplementary Figure 1 from Aberrant Vimentin Methylation Is Characteristic of Upper Gastrointestinal Pathologies
Supplementary Figure 1 from Aberrant Vimentin Methylation Is Characteristic of Upper Gastrointestinal Pathologies Open
PDF file - 41K
View article: Supplementary Table 1 from Aberrant Vimentin Methylation Is Characteristic of Upper Gastrointestinal Pathologies
Supplementary Table 1 from Aberrant Vimentin Methylation Is Characteristic of Upper Gastrointestinal Pathologies Open
PDF file - 189K
View article: Data from Aberrant Vimentin Methylation Is Characteristic of Upper Gastrointestinal Pathologies
Data from Aberrant Vimentin Methylation Is Characteristic of Upper Gastrointestinal Pathologies Open
Background: We have previously established aberrant DNA methylation of vimentin exon-1 (VIM methylation) as a common epigenetic event in colon cancer and as a biomarker for detecting colon neoplasia. We now examine vimentin methylation in …
View article: Supplemental Table S1 from Methylated <i>B3GAT2</i> and <i>ZNF793</i> Are Potential Detection Biomarkers for Barrett's Esophagus
Supplemental Table S1 from Methylated <i>B3GAT2</i> and <i>ZNF793</i> Are Potential Detection Biomarkers for Barrett's Esophagus Open
Supplemental Table S1. Clinical Characteristics of Samples
View article: Novel DNA Methylation Biomarker Panel for Detection of Esophageal Adenocarcinoma and High-Grade Dysplasia
Novel DNA Methylation Biomarker Panel for Detection of Esophageal Adenocarcinoma and High-Grade Dysplasia Open
Purpose: Current endoscopy-based screening and surveillance programs have not been proven effective at decreasing esophageal adenocarcinoma (EAC) mortality, creating an unmet need for effective molecular tests for early detection of this h…