Helen Trottier
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View article: IgG and IgM Seroreactivity Against Natural HPV16 Infection and <i>HLA‐DRB1</i> and <i>‐DQB1</i> Polymorphism
IgG and IgM Seroreactivity Against Natural HPV16 Infection and <i>HLA‐DRB1</i> and <i>‐DQB1</i> Polymorphism Open
Little is known about the factors associated with the natural humoral immune response against human papillomavirus (HPV) infection. The association between HLA‐DRB1 and ‐DQB1 polymorphism and (1) HPV16 DNA detection, (2) naturally develope…
View article: The use of physiologic markers of anemia intolerance to guide transfusion practice in pediatric intensive care units: an international survey
The use of physiologic markers of anemia intolerance to guide transfusion practice in pediatric intensive care units: an international survey Open
Objectives To explore how red blood cell (RBC) transfusion practice of pediatric intensivists is modulated by physiologic markers of anemia intolerance, in addition to the hemoglobin (Hb) concentration. Background Most research to date has…
View article: Human Papillomavirus Persistence, Recurrence, and Incidence in Early Childhood
Human Papillomavirus Persistence, Recurrence, and Incidence in Early Childhood Open
Background Little is known on the vertical transmission of human papillomavirus (HPV) and on the dynamics of HPV among children. Our objective was to determine the risk of HPV recurrence, persistence, and incidence over 2 years of age amon…
View article: Viral Load of Human Papillomavirus (HPV) During Pregnancy and Its Association With HPV Vertical Transmission
Viral Load of Human Papillomavirus (HPV) During Pregnancy and Its Association With HPV Vertical Transmission Open
Little is known on the dynamics of human papillomavirus (HPV) viral load during pregnancy and on the impact of viral load on HPV vertical transmission. We described viral loads for several genotypes during pregnancy and analyse its associa…
View article: Risk evaluation and recipient selection in adult liver transplantation: A mixed-methods survey
Risk evaluation and recipient selection in adult liver transplantation: A mixed-methods survey Open
Background: Liver transplant (LT) is the definitive treatment for end-stage liver disease. Limited resources and important post-operative implications for recipients compel judicious risk stratification and patient selection. However, litt…
View article: Naturally developed HPV16 antibodies and risk of newly detected cervical HPV infection outcomes
Naturally developed HPV16 antibodies and risk of newly detected cervical HPV infection outcomes Open
Little is known about the protection conferred by antibodies from natural human papillomavirus (HPV) infection. Our objective was to evaluate the association between HPV16 seroreactivity and HPV16 redetection, newly detected HPV infections…
View article: The effects of vitamin D supplementation on inflammatory biomarkers in patients with asthma: a systematic review and meta-analysis of randomized controlled trials
The effects of vitamin D supplementation on inflammatory biomarkers in patients with asthma: a systematic review and meta-analysis of randomized controlled trials Open
Background While the association between vitamin D and several inflammatory biomarkers in asthma patients has been extensively reported, it remains unclear whether supplementation modifies these biomarkers. This review aims to evaluate the…
View article: Association between the Mode of Delivery and Vertical Transmission of Human Papillomavirus
Association between the Mode of Delivery and Vertical Transmission of Human Papillomavirus Open
Human papillomavirus (HPV) can be vertically transmitted. Our objective was to measure the association between the mode of delivery and the detection of HPV in infants. We used data collected from pregnant women during the HERITAGE study. …
View article: Association between Human Papillomavirus 16 Viral Load in Pregnancy and Preterm Birth
Association between Human Papillomavirus 16 Viral Load in Pregnancy and Preterm Birth Open
Recent evidence shows increased preterm birth risk with human papillomavirus-16 (HPV16) infection during pregnancy. This study aimed to measure the association between HPV16 viral load during pregnancy and preterm birth. We used data from …
View article: Predictors of High-grade Squamous Intraepithelial Lesion treatment failure
Predictors of High-grade Squamous Intraepithelial Lesion treatment failure Open
Objective To estimate the association between several risk factors and high-grade squamous intraepithelial lesions (HSIL) treatment failure in order to identify predictors. Methods The study population included 1,548 Canadian women treated…
View article: Human Papillomavirus Transmission and Persistence in Pregnant Women and Neonates
Human Papillomavirus Transmission and Persistence in Pregnant Women and Neonates Open
Importance The prevalence of human papillomavirus (HPV) infection during pregnancy and its risk of transmission to newborns are not well documented. Objective To ascertain the prevalence of HPV in pregnant women, the risk of HPV detection …
View article: Individual, Independent, and Joint Associations of Toxic Metals and Manganese on Hypertensive Disorders of Pregnancy: Results from the MIREC Canadian Pregnancy Cohort
Individual, Independent, and Joint Associations of Toxic Metals and Manganese on Hypertensive Disorders of Pregnancy: Results from the MIREC Canadian Pregnancy Cohort Open
Our results confirm that even low blood Pb concentrations are a risk factor for preeclampsia. Women with higher blood As concentrations combined with lower Mn in early pregnancy were more likely to develop gestational hypertension. These p…
View article: Human Papillomavirus Intermittence and Risk Factors Associated With First Detections and Redetections in the Ludwig-McGill Cohort Study of Adult Women
Human Papillomavirus Intermittence and Risk Factors Associated With First Detections and Redetections in the Ludwig-McGill Cohort Study of Adult Women Open
Background We assessed the incidence and risk factors for first detection and redetection with the same human papillomavirus (HPV) genotype, and prevalence of cytological lesions during HPV redetections. Methods The Ludwig-McGill cohort st…
View article: Endoscopic Ultrasound Guided Fine Needle Aspiration versus Endoscopic Ultrasound Guided Fine Needle Biopsy for Pancreatic Cancer Diagnosis: A Systematic Review and Meta-Analysis
Endoscopic Ultrasound Guided Fine Needle Aspiration versus Endoscopic Ultrasound Guided Fine Needle Biopsy for Pancreatic Cancer Diagnosis: A Systematic Review and Meta-Analysis Open
Introduction: One of the most effective diagnostic tools for pancreatic cancer is endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) or biopsy (EUS-FNB). Several randomized clinical trials have compared different EUS tissue samp…
View article: Human papillomavirus intermittence, redetections, and associated risk of cytological abnormalities in the Ludwig-McGill cohort study of adult women
Human papillomavirus intermittence, redetections, and associated risk of cytological abnormalities in the Ludwig-McGill cohort study of adult women Open
Introduction We assessed the incidence of redetection with the same human papillomavirus (HPV) genotype, predictors of first HPV detections and redetections, and prevalence of cytological lesions during HPV redetections. Methods The Ludwig…
View article: Integrating Gestational Diabetes Screening and Care and Type 2 Diabetes Mellitus Prevention After GDM Into Community Based Primary Health Care in South Africa-Mixed Method Study
Integrating Gestational Diabetes Screening and Care and Type 2 Diabetes Mellitus Prevention After GDM Into Community Based Primary Health Care in South Africa-Mixed Method Study Open
GDM screening and post-GDM prevention of T2DM are poorly integrated into PHC services in South Africa. Integration is desired by stakeholders (patients and providers) and may be feasible if PHC resource, training constraints and women's so…
View article: Integrated Management of Type 2 Diabetes and Gestational Diabetes in the Context of Multi-Morbidity in Africa: A Systematic Review
Integrated Management of Type 2 Diabetes and Gestational Diabetes in the Context of Multi-Morbidity in Africa: A Systematic Review Open
Though few, integrated interventions for screening and/or care of DM in the context of multimorbidity within available resources in health systems throughout Africa exist and suggest that this approach is possible and could improve health …
View article: Intravenous Immunoglobulin Use In Critically Ill Children
Intravenous Immunoglobulin Use In Critically Ill Children Open
Purpose The use of intravenous immunoglobulins (IVIG) has increased significantly in the last decade causing challenges for blood suppliers to respond to the demand. Indications for which IVIG infusion should be given to critically ill chi…
View article: Association Between Human Papillomavirus Infection Among Pregnant Women and Preterm Birth
Association Between Human Papillomavirus Infection Among Pregnant Women and Preterm Birth Open
The study's results suggest that persistent HPV-16/18 infection is associated with an increased risk of preterm birth, independent of cervical treatment. Future studies should investigate the association of HPV vaccination and vaccination …
View article: Association between Antiviral Prophylaxis and Cytomegalovirus and Epstein–Barr Virus DNAemia in Pediatric Recipients of Allogeneic Hematopoietic Stem Cell Transplant
Association between Antiviral Prophylaxis and Cytomegalovirus and Epstein–Barr Virus DNAemia in Pediatric Recipients of Allogeneic Hematopoietic Stem Cell Transplant Open
Background: Epstein–Barr virus (EBV) and cytomegalovirus (CMV) infections can have serious consequences during the period of aplasia and lymphopenia following hematopoietic stem cell transplantation (HSCT). Large pediatric cohort studies e…
View article: Factors Associated with Post-Transplant Active Epstein-Barr Virus Infection and Lymphoproliferative Disease in Hematopoietic Stem Cell Transplant Recipients: A Systematic Review and Meta-Analysis
Factors Associated with Post-Transplant Active Epstein-Barr Virus Infection and Lymphoproliferative Disease in Hematopoietic Stem Cell Transplant Recipients: A Systematic Review and Meta-Analysis Open
This systematic review was undertaken to identify risk factors associated with post-transplant Epstein–Barr virus (EBV) active infection and post-transplant lymphoproliferative disease (PTLD) in pediatric and adult recipients of hematopoie…
View article: Integrating gestational diabetes and type 2 diabetes care into primary health care: Lessons from prevention of mother-to-child transmission of HIV in South Africa - A mixed methods study
Integrating gestational diabetes and type 2 diabetes care into primary health care: Lessons from prevention of mother-to-child transmission of HIV in South Africa - A mixed methods study Open
Background Implementation of the programmes for the Prevention of Mother to Child Transmission (PMTCT) of Human Immunodeficiency Virus (HIV) into antenatal care over the last three decades could inform implementation of interventions for o…
View article: A randomized noninferiority trial comparing the diagnostic yield of the 25G ProCore needle to the standard 25G needle in suspicious pancreatic lesions
A randomized noninferiority trial comparing the diagnostic yield of the 25G ProCore needle to the standard 25G needle in suspicious pancreatic lesions Open
The 25S needle is noninferior to the 25P needle for diagnosing cancer in suspicious pancreatic lesions.