Hélène Sanfaçon
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View article: Summary of taxonomy changes ratified by the International Committee on Taxonomy of Viruses from the Plant Viruses Subcommittee, 2025
Summary of taxonomy changes ratified by the International Committee on Taxonomy of Viruses from the Plant Viruses Subcommittee, 2025 Open
In March 2025, following the annual International Committee on Taxonomy of Viruses (ICTV) ratification vote, newly proposed taxa were added to those under the mandate of the Plant Viruses Subcommittee. In brief, 1 new order, 3 new families…
View article: AlphaFold modeling of nepovirus 3C-like proteinases provides new insights into their diverse substrate specificities
AlphaFold modeling of nepovirus 3C-like proteinases provides new insights into their diverse substrate specificities Open
The majority of picornaviral 3C proteinases (3Cpro) cleavage sites possess glutamine at the P1 position. Plant nepovirus 3C-like proteinases (3CLpro) show however much broader specificity, cleaving not only after glut…
View article: Alphafold Modeling of Nepovirus 3c-Like Proteinases Provides New Insights into Their Diverse Specificities
Alphafold Modeling of Nepovirus 3c-Like Proteinases Provides New Insights into Their Diverse Specificities Open
View article: ICTV Virus Taxonomy Profile: Secoviridae 2022
ICTV Virus Taxonomy Profile: Secoviridae 2022 Open
Members of the family Secoviridae are non-enveloped plant viruses with mono- or bipartite linear positive-sense ssRNA genomes with a combined genome of 9 to 13.7 kb and icosahedral particles 25–30 nm in diameter. They are related to picorn…
View article: Characterizing the Virome of Apple Orchards Affected by Rapid Decline in the Okanagan and Similkameen Valleys of British Columbia (Canada)
Characterizing the Virome of Apple Orchards Affected by Rapid Decline in the Okanagan and Similkameen Valleys of British Columbia (Canada) Open
Rapid apple decline disease (RAD) has been affecting orchards in the USA and Canada. Although the primary cause for RAD remains unknown, viruses may contribute to the incidence or severity of the disease. We examined the diversity and prev…
View article: Re-examination of nepovirus polyprotein cleavage sites highlights the diverse specificities and evolutionary relationships of nepovirus 3C-like proteases
Re-examination of nepovirus polyprotein cleavage sites highlights the diverse specificities and evolutionary relationships of nepovirus 3C-like proteases Open
View article: Proteolytic Processing of Plant Proteins by Potyvirus NIa Proteases
Proteolytic Processing of Plant Proteins by Potyvirus NIa Proteases Open
Viruses are highly adaptive and use multiple molecular mechanisms to highjack or modify the cellular resources to their advantage. They must also counteract or evade host defense responses.
View article: The new scope of virus taxonomy: partitioning the virosphere into 15 hierarchical ranks
The new scope of virus taxonomy: partitioning the virosphere into 15 hierarchical ranks Open
View article: <i>Strawberry Mottle Virus</i> (Family <i>Secoviridae</i> , Order <i>Picornavirales</i> ) Encodes a Novel Glutamic Protease To Process the RNA2 Polyprotein at Two Cleavage Sites
<i>Strawberry Mottle Virus</i> (Family <i>Secoviridae</i> , Order <i>Picornavirales</i> ) Encodes a Novel Glutamic Protease To Process the RNA2 Polyprotein at Two Cleavage Sites Open
Many viruses encode proteases to release mature proteins and intermediate polyproteins from viral polyproteins. Polyprotein processing allows regulation of the accumulation and activity of viral proteins. Many viral proteases also cleave h…
View article: Exploring the Diversity of Mechanisms Associated With Plant Tolerance to Virus Infection
Exploring the Diversity of Mechanisms Associated With Plant Tolerance to Virus Infection Open
Tolerance is defined as an interaction in which viruses accumulate to some degree without causing significant loss of vigor or fitness to their hosts. Tolerance can be described as a stable equilibrium between the virus and its host, an in…
View article: Corrigendum: Identification of Cleavage Sites Recognized by the 3C-Like Cysteine Protease within the Two Polyproteins of Strawberry Mottle Virus
Corrigendum: Identification of Cleavage Sites Recognized by the 3C-Like Cysteine Protease within the Two Polyproteins of Strawberry Mottle Virus Open
In the original article, there were mistakes in Table 2 as published. Several listed cleavage sites were derived from virus isolates that did not correspond to the accession numbers provided in the Materials and Methods section. In additio…
View article: Grand Challenge in Plant Virology: Understanding the Impact of Plant Viruses in Model Plants, in Agricultural Crops, and in Complex Ecosystems
Grand Challenge in Plant Virology: Understanding the Impact of Plant Viruses in Model Plants, in Agricultural Crops, and in Complex Ecosystems Open
SPECIALTY GRAND CHALLENGE article Front. Microbiol., 24 May 2017Sec. Virology Volume 8 - 2017 | https://doi.org/10.3389/fmicb.2017.00860
View article: Identification of Cleavage Sites Recognized by the 3C-Like Cysteine Protease within the Two Polyproteins of Strawberry Mottle Virus
Identification of Cleavage Sites Recognized by the 3C-Like Cysteine Protease within the Two Polyproteins of Strawberry Mottle Virus Open
Strawberry mottle virus (SMoV, family Secoviridae, order Picornavirales) is one of several viruses found in association with strawberry decline disease in Eastern Canada. The SMoV genome consists of two positive-sense single-…
View article: ICTV Virus Taxonomy Profile: Secoviridae
ICTV Virus Taxonomy Profile: Secoviridae Open
Members of the family Secoviridae are non-enveloped viruses with mono- or bipartite (RNA-1 and RNA-2) linear positive-sense ssRNA genomes with the size of the RNAs combined ranging from 9 to 13.7 kb. They are related to picornaviruses and …
View article: 50 years of the International Committee on Taxonomy of Viruses: progress and prospects
50 years of the International Committee on Taxonomy of Viruses: progress and prospects Open
We mark the 50th anniversary of the International Committee on Taxonomy of Viruses (ICTV) by presenting a brief history of the organization since its foundation, showing how it has adapted to advancements in our knowledge of virus diversit…
View article: Creation of new order, Ortervirales, for 5 families of reverse-transcribing viruses
Creation of new order, Ortervirales, for 5 families of reverse-transcribing viruses Open
View article: Possibility and Challenges of Conversion of Current Virus Species Names to Linnaean Binomials
Possibility and Challenges of Conversion of Current Virus Species Names to Linnaean Binomials Open
Botanical, mycological, zoological, and prokaryotic species names follow the Linnaean format, consisting of an italicized Latinized binomen with a capitalized genus name and a lower case species epithet (e.g., Homo sapiens). Virus species …
View article: Plant Translation Factors and Virus Resistance
Plant Translation Factors and Virus Resistance Open
Plant viruses recruit cellular translation factors not only to translate their viral RNAs but also to regulate their replication and potentiate their local and systemic movement. Because of the virus dependence on cellular translation fact…