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View article: AUT-MENU Project: A Bicentric Intervention Study to Improve the Meal Acceptance of Subjects with Autism Spectrum Disorder
AUT-MENU Project: A Bicentric Intervention Study to Improve the Meal Acceptance of Subjects with Autism Spectrum Disorder Open
Background/Objectives: Individuals with Autism Spectrum Disorder (ASD) often exhibit low dietary diversity due to Food Selectivity (FS), leading to various forms of malnutrition, such as obesity and/or micronutrient deficiencies. The main …
View article: Obesity in Tanzanian Youth (15–35 Years): From Nutrition Transition to Policy Action—A Scoping Review
Obesity in Tanzanian Youth (15–35 Years): From Nutrition Transition to Policy Action—A Scoping Review Open
Background: Tanzania is undergoing a rapid nutrition and epidemiological transition that has shifted dietary patterns and lifestyles toward more Westernised models, contributing to an increase in diet-related non-communicable diseases (NCD…
View article: Exploring the interplay between diet, obesity, mental health, and the gut microbiota: the MIND-GUT intervention study, study protocol
Exploring the interplay between diet, obesity, mental health, and the gut microbiota: the MIND-GUT intervention study, study protocol Open
Background Obesity and mental health disorders often co-occur, contributing to individual suffering and healthcare costs. Diet plays a key role in both weight management and mental wellbeing and may influence these through its impact on th…
View article: Highly Processed Food and Functional Gastrointestinal Disorders in Children and Adolescents with Obesity: The Preventive Challenge—A Narrative Review
Highly Processed Food and Functional Gastrointestinal Disorders in Children and Adolescents with Obesity: The Preventive Challenge—A Narrative Review Open
Objective: This narrative review summarizes current evidence on the associations between ultra-processed food (UPF) consumption, childhood and adolescent obesity, and functional gastrointestinal disorders (FGIDs), and examines the metaboli…
View article: Nudging Healthier and More Sustainable Eating Habits in University Cafeterias: The FOOD-HACK Project
Nudging Healthier and More Sustainable Eating Habits in University Cafeterias: The FOOD-HACK Project Open
Background/Objectives: The global syndemic of obesity, undernutrition, and climate change highlight the complex health and environmental challenges faced by young adults. These challenges may intensify during the transition to university. …
View article: Exposome, oxidative stress and inflammation in persons with multiple sclerosis: the EXPOSITION study protocol
Exposome, oxidative stress and inflammation in persons with multiple sclerosis: the EXPOSITION study protocol Open
The exposome represents the totality of external and internal exposures an individual encounters throughout life and plays a critical role in developing many chronic diseases, including multiple sclerosis (MS). MS is a multifactorial disea…
View article: Offspring's exposome: a narrative review on the influence of early-life factors on childhood obesity risk
Offspring's exposome: a narrative review on the influence of early-life factors on childhood obesity risk Open
Childhood obesity has emerged as a global health challenge, with significant long-term health consequences, including an increased risk of non-communicable diseases. The “first 1,000 days” period of life is a critical window for shaping lo…
View article: Urban Health Assessment Through a Planetary Health Perspective: Methods and First Results from the Rome NBFC Experiment
Urban Health Assessment Through a Planetary Health Perspective: Methods and First Results from the Rome NBFC Experiment Open
Addressing the planetary crisis associated with climate change, biodiversity loss, global pollution, and public health requires novel and holistic approaches. Here, we present the methodology and initial results of an experiment conducted …
View article: Clustering of Exposome and Lifestyle Data to Support Differential Expression Analysis of Circulating miRNAs in Multiple Sclerosis
Clustering of Exposome and Lifestyle Data to Support Differential Expression Analysis of Circulating miRNAs in Multiple Sclerosis Open
Introduction:MicroRNAs (miRNAs) are small non-coding RNAs that regulate gene expression post-transcriptionally and are influenced by various metabolic and environmental factors[1]. The functional exposome concept can be seen as a new strat…
View article: Insights from the EXPOSITION Study: Exposome-related microRNA Expression and Clinical Outcomes in People with multiple sclerosis
Insights from the EXPOSITION Study: Exposome-related microRNA Expression and Clinical Outcomes in People with multiple sclerosis Open
IntroductionMicroRNAs (miRNAs) are emerging as promising biomarkers of neuroinflammation and may capture the influence of lifestyle and environmental exposures in people with multiple sclerosis (pwMS). The EXPOSITION study[1] aims to eluci…
View article: Higher dietary species richness is associated with better diet quality in adults: results from the Italian IV-SCAI survey
Higher dietary species richness is associated with better diet quality in adults: results from the Italian IV-SCAI survey Open
Dietary species richness (DSR) is key to food security and nutrient adequacy, but only recently has attracted research attention in Europe. This is the first analysis to assess food biodiversity through DSR in Italian adults, considering i…
View article: Intertwined paths: exploring the link between oral diseases and eating disorders. A comprehensive narrative review
Intertwined paths: exploring the link between oral diseases and eating disorders. A comprehensive narrative review Open
Eating disorders (ED) are psychiatric conditions with profound impacts on physical health, emotional well-being and quality of life. They are associated with reduced employment participation and increased healthcare costs, representing a s…
View article: Lights and Shadows of a Primary School-Based Nutrition Education Program in Italy: Insights from the LIVELY Project
Lights and Shadows of a Primary School-Based Nutrition Education Program in Italy: Insights from the LIVELY Project Open
Background/Objectives: Childhood obesity represents a pressing global health challenge, demanding coordinated, long-term strategies. Schools and families are pivotal environments for shaping children’s lifestyle behaviors. The LIVELY proje…
View article: Thyroid Health and Selenium: The Critical Role of Adequate Intake from Fetal Development to Adolescence
Thyroid Health and Selenium: The Critical Role of Adequate Intake from Fetal Development to Adolescence Open
The thyroid gland plays a crucial role in regulating metabolism and supporting development through the production of the hormones T4 and T3. These hormones are essential during childhood for nervous system myelination, physical growth, pub…
View article: Unlocking the Link: Exploring the Association Between Food Selectivity and Health Outcome in Autism Spectrum Disorder—A Systematic Review
Unlocking the Link: Exploring the Association Between Food Selectivity and Health Outcome in Autism Spectrum Disorder—A Systematic Review Open
Context Individuals with autism spectrum disorder (ASD) often face behavioral challenges during meals, such as food refusal and restricted food consumption, which encompass the concept of food selectivity (FS). The exclusion of food groups…
Development and Application of an In-Capillary CE-DAD Method for the Inhibitory Screening of Natural Extracts Towards Acetylcholinesterase Enzyme Open
Background: The enzymatic activity of acetylcholinesterase (AChE) has been a focal point in neurodegenerative diseases research, particularly in relation to Alzheimer’s disease. This is attributed to the significantly reduced levels of cho…
FACILITY: feeding the family—the intergenerational approach to fight obesity, a cross-sectional study protocol Open
Introduction Paediatric obesity has been described by the World Health Organization as one of the most serious health challenges of the 21st century. Over the past four decades, the number of children and adolescents with obesity has incre…
The Interplay Between Iron Metabolism and Insulin Resistance: A Key Factor in Optimizing Obesity Management in Children and Adolescents Open
Iron plays a vital role in insulin signaling, regulating molecular mechanisms that influence cellular insulin responses. This review explores the link between iron metabolism and insulin resistance (IR) in children and adolescents with obe…
View article: Improving Meal Acceptance of Individuals With Autism Spectrum Disorder (AUT-MENU Project): Protocol for a Bicentric Intervention Study
Improving Meal Acceptance of Individuals With Autism Spectrum Disorder (AUT-MENU Project): Protocol for a Bicentric Intervention Study Open
Background Individuals with autism spectrum disorder (ASD) often exhibit low dietary diversity due to food selectivity, leading to various forms of malnutrition, such as obesity or micronutrient deficiencies. Objective The main objective o…
Building the Future of Biodiversity: Italy's National Biodiversity Future Center (NBFC) Initiative Open
This presentation provides an overview of a recent initiative and large investment in biodiversity undertaken in Italy. It focuses on establishing the Italian National Biodiversity Future Center (NBFC), the first National Research and Inno…
Italian Biodiversity: A Source of Edible Plant Extracts with Protective Effects Against Advanced Glycation End Product-Related Diseases Open
Background: Italy’s plant biodiversity, characterized by many plant species, is an important source of bioactive secondary metabolites that help reduce the risk of the development of advanced glycation end product (AGE)-related diseases. A…
View article: Metabolomic Profiling and In Vitro Evaluation of Cytotoxic, Genotoxic, and Antigenotoxic Effects of Staphylea pinnata L. Extract from Italian Flora
Metabolomic Profiling and In Vitro Evaluation of Cytotoxic, Genotoxic, and Antigenotoxic Effects of Staphylea pinnata L. Extract from Italian Flora Open
Staphylea pinnata L., (S. pinnata), has long been recognized in Europe as both a wild food source and a traditional medicinal. This study aimed to characterize the metabolomic profile of the leaf extract of S. pinnata and assess its cytoto…
View article: From Pregnancy to Breastfeeding: The Role of Maternal Exercise in Preventing Childhood Obesity
From Pregnancy to Breastfeeding: The Role of Maternal Exercise in Preventing Childhood Obesity Open
Low adherence to healthy lifestyle behaviors during pregnancy and lactation is strongly associated with a higher risk of childhood obesity. This narrative review aims to elucidate and summarize the pivotal role played by physical activity …
View article: Functional Gastrointestinal Disorders and Childhood Obesity: The Role of Diet and Its Impact on Microbiota
Functional Gastrointestinal Disorders and Childhood Obesity: The Role of Diet and Its Impact on Microbiota Open
Introduction Emerging evidence suggests an association between obesity and Functional Gastrointestinal Disorders (FGIDs). Childhood obesity and FGIDs share many common features, such as high prevalence in the pediatric population, risk fac…
View article: Improving Meal Acceptance of Individuals With Autism Spectrum Disorder (AUT-MENU Project): Protocol for a Bicentric Intervention Study (Preprint)
Improving Meal Acceptance of Individuals With Autism Spectrum Disorder (AUT-MENU Project): Protocol for a Bicentric Intervention Study (Preprint) Open
BACKGROUND Individuals with autism spectrum disorder (ASD) often exhibit low dietary diversity due to food selectivity, leading to various forms of malnutrition, such as obesity or micronutrient deficiencies. OBJECTIVE The main objective o…
View article: Phytochemical Profile and In Vitro Cytotoxic, Genotoxic, and Antigenotoxic Evaluation of Cistus monspeliensis L. Leaf Extract
Phytochemical Profile and In Vitro Cytotoxic, Genotoxic, and Antigenotoxic Evaluation of Cistus monspeliensis L. Leaf Extract Open
Cistus monspeliensis L. (C. monspeliensis) is used in Italian folk medicine. This study was performed to determine genotoxic and antigenotoxic effects of C. monspeliensis leaf extract against mitomycin C (MMC) using an in vitro cytokinesis…
View article: Planetary Health Diet for Childhood Obesity Prevention: Integrating Nutritional Health with Environmental Stewardship
Planetary Health Diet for Childhood Obesity Prevention: Integrating Nutritional Health with Environmental Stewardship Open
Background: Childhood obesity is a critical public health challenge with a rising prevalence worldwide, contributing to numerous health risks and long-term societal burdens. Concurrently, climate change and environmental degradation demand…